1st Workshop on Virus Dynamics

Lecture Programme

                                                                                                                           (Last update on 3 July 2013)



Monday, 15 July 2013

                                                                                                          Room: Franz-Patat-Hörsaal (3rd floor)

08:30 Opening and Introduction

            VIRUS REPLICATION AT THE INTERCELLULAR LEVEL
           
Chair: A.S. Perelson, Los Alamos National Laboratory, NM/USA

08:50

Keynote
Modeling hepatitis C virus dynamics in vitro

H. Dahari, Loyola Univeristy Chicago, Maywood, IL/USA and Los Alamos National Laboratory, NM/USA

09:30 Mathematical modeling of the intracellular hepatitis C virus replication
L. Kaderali, M. Binder, N. Sulaimanov, D. Clausznitzer, M. Schulze, C.M. Hüber,
S.M. Lenz, J.P. Schlöder, M. Trippler, R. Bartenschlager, V. Lohmann, TU Dresden/D
10:00 Coffee Break

            MODELS OF SIMPLE IN VITRO VIRAL INFECTION SYSTEMS I
            Chair: U. Reichl, Max Planck Institute for Dynamics of Complex Technical Systems,
                        Magdeburg/D 

10:20 Keynote
Modeling influenza A viral infections in vitro
C.A.A. Beauchemin, Ryerson University, Toronto, ON/CDN
11:00 Multi-scale modeling of influenza virus infection elucidates the performance of antivirals
F.S. Heldt, B. Isken, A. Pflugmacher, T. Frensing, Max Planck Institute for Dynamics of Complex Technical Systems, Magdeburg/D; U. Reichl, Max Planck Institute for Dynamics of Complex Technical Systems and Otto von Guericke University Magdeburg/D
11:30 Cell cycle based calculations of the in vitro baculovirus life cycle
C. Lindenberger, FAU Busan/ROK; R. Buchholz, Universität Erlangen-Nürnberg/D
12:00 Lunch Break
            MODELS OF SIMPLE IN VITRO VIRAL INFECTION SYSTEMS II
            Chair: C.A.A. Beauchemin, Ryerson University, Toronto, ON/CDN
13:30 Keynote
Population balance modeling of influenza virus replication during vaccine production
A. Kienle, Max Planck Institute for Dynamics of Complex Technical Systems and Otto von Guericke University Magdeburg/D
14:10 Spatial virus dynamics and the spread of oncolytic viruses
D. Wodarz, A. Hofacre, Z. Sun, H. Fan, N. Komarova, J. Lau, University of California, Irvine, CA/USA
14:40 Mathematical modeling of cell culture experiment reveals a critical difference among viral strains - A case study of simian/human immunodeficiency virus (SHIV)S. Iwami, Kyushu University, Fukuoka/J; R. de Boer, Utrecht University/NL; Y. Koizumi, Kanazawa University/J; T. Igarashi, T. Miura, Kyoto University/J
15:10 SHORT POSTER PRESENTATIONS
15:55  Coffee Break
            IN VIVO MODELING AND HOW TO IMPLEMENT THE IMMUNE RESPONSE I
           
Chair: A.S. Perelson, Los Alamos National Laboratory, NM/USA
16:30 Keynote
How to further improve our models - some thoughts

A. Handel, University of Georgia, Athens, GA/USA
17:10

Assessing mathematical models of influenza infections using features of the immune response
H.M. Dobrovolny, Texas Christian University, Fort Worth, TX/USA; M.B. Reddy, Array Biopharma Inc., Boulder, CO/USA; M.A. Kamal, F. Hoffmann-La Roche Inc., Nutley, NJ/USA; C.R. Rayner, 3d Ltd. and Monash University, Melbourne, VIC/AUS; C.A.A. Beauchemin, Ryerson University, Toronto, ON/CDN

17:40 Kinetics of influenza coinfection in mice
A. Smith, St. Jude Children's Research Hospital, Memphis, TN/USA; F. Adler, University of Utah, Salt Lake City, UT/USA; R. Ribeiro, Los Alamos National Laboratory, NM/USA; R. Gutenkunst, University of Arizona, Tucson, AZ/USA; J. McAuley, University of Melbourne, VIC/AUS; J. McCullers, St. Jude Children's Research Hospital, Memphis, TN/USA; A. Perelson, Los Alamos National Laboratory, NM/USA
18:10 End of the conference day
20:00 - 22:00

Conference Dinner - registration required  
(click here for more information)

 


 

Tuesday, 16 July 2013

                                                                                                          Room: Franz-Patat-Hörsaal (3rd floor)

            IN VIVO MODELING AND HOW TO IMPLEMENT THE IMMUNE RESPONSE II
           
Chair: H. Wu, University of Rochester, NY/USA

08:50 Keynote
Modeling the battle between virus and host defense on varied terrain

T. Höfer, German Cancer Research Center (DKFZ), Heidelberg/D
09:30

The effects of aging on influenza virus infection dynamics
E.A. Hernandez-Vargas, S. Binder, Helmholtz Centre for Infection Research, Braunschweig/D; A.S. Perelson, Los Alamos National Laboratory, NM/USA; F.R. Toapanta, University of Maryland, MD/USA; M. Meyer-Hermann, Helmholtz Centre for Infection Research, Braunschweig/D

10:00 Coffee Break
            IN VIVO MODELING AND HOW TO IMPLEMENT THE IMMUNE RESPONSE III
           
Chair: H. Dahari, Loyola Univeristy Chicago, Maywood, IL/USA 
                        and Los Alamos National Laboratory, NM/USA
10:20 Keynote
Modeling HCV infection in vivo

A.S. Perelson, Los Alamos National Laboratory, NM/USA
11:00 Modeling the immune response dynamics following hepatitis B virus infection
S. Ciupe, Virginia Tech, Blacksburg, VA/USA
11:30 Inferring viral dynamics in chronically HCV infected patients from the spatial distribution of infected hepatocytes
F. Graw, Heidelberg University/D; A. Balagopal, S. Ray, A. Kandathil, D.L. Thomas, Johns Hopkins University, Baltimore, MD/USA; R.M. Ribeiro, A.S. Perelson, Los Alamos National Laboratory, NM/USA
12:00 Lunch Break
13:30 Modeling early viral kinetics with alisporivir: interferon-free treatment and SVR predictions in HCV G2/3 patients
J. Guedj, INSERM U738, Paris/F; J. Yu, Novartis, Cambridge, MA/USA; M. Levi, Novartis, East Hannover, NJ/USA; B. Li, Novartis, Cambridge, MA/USA; S. Kern, N. Naoumov, Novartis, Basel/CH; A.S. Perelson, Los Alamos National Laboratory, NM/USA
14:00 dsRNA recognition by the RIG-I innate immunity pathway
D. Clausznitzer, TU Dresden/D; M. Binder, University of Heidelberg/D; T. Becker, University of Mainz/D; F. Eberle, R. Bartenschlager, University of Heidelberg/D;  L. Kaderali, TU Dresden/D
14:30 Coffee Break
            COMPUTATIONAL TOOLS AND THEORETICAL ASPECTS
           
Chair: A. Handel, University of Georgia, Athens, GA/USA
14:50   Keynote

Modeling immune responses to viral infections at multi-scale system levels: inverse problems for both model structures and parameters
H. Wu, University of Rochester, NY/USA

Last minute change      
15:50 WRAP-UP                                                                                                             
 16:10 End of the conference                                                                                                                   
 17:00 Guided walking tour of Frankfurt - registration required  

(click  here for more information)

 

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