Ten years ago the term "Metabolomics", which defines the entire metabolic content of a cell or organism at a given time point, was introduced to the scientific community. Monitoring results of qualitative and quantitative analysis of a high number of metabolites reflects the functional status of biological entities at the fundamental metabolic basis. During the last decade, metabolomics closed an important gap in the area of post genome research. Determining the information flow from genome to transcriptome, proteome and finally metabolome allows, for the first time, a comprehensive description of living systems. To establish models and data sets for a precise simulation and prediction of physiological properties of cells, however, in silico reconstructions of metabolic pathways and high performance empirical metabolomic studies technologies are essential. The next logical step in metabolomics is to link metabolite pool measurements with metabolic fluxes and gene regulation, to fully cover the dynamics of living systems. Beside the causal analysis of living systems, metabolomics is ideally suited to search for novel biomarkers in disease detection or in monitoring the success of pharmacological intervention. Further aspects of metabolomics range from biotechnology to environmental sensing to food quality applications.
This second metabolomics meeting hosted by the DECHEMA will cover trends ranging from technical developments in analytics, integration of metabolomics into systems biology to biomarker discovery in nutrition and medical research.
In the afternoon of June 3rd, a meeting for young scientists will precede the conference. PhD students and post-docs can briefly present their research and discuss problems with scientists. A tutorial lecture on bioinformatics for metabolomics will be held by Steffen Neumann, Leibniz-Institute, Halle, Germany. The afternoon will close with an informal get-together (paricipation free of charge).
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