9th Status Seminar Chemical Biology

Poster programme

P 01 ANCHOR.QUERY: discovery of p53/mdm2/mdmx protein protein antagonists
A. Doemling, University of Groningen/NL; K. Khoury, Y. Huang, University of Pittsburgh, PA/USA; E. Wrona, G. Popowicz, Jagiellonian University, Cracow/PL; B. Beck, Helmholtz Zentrum München/D; D. Koes, C. Camacho, University of Pittsburgh, PA/USA; T. Holak, Jagiellonian University, Cracow/PL
P 02 NucleoQuery - the open source drug-designer software
for the design and synthesis of human DeoxyuridineTriphosphatase (dUTPase) inhibitors

T. Zarganis - Tzitzikas, University of Groningen/NL; K. Khoury, C. Camacho, D. Koes, University of Pittsburgh, PA/USA; A. Dömling, University of Groningen/NL
P 03 Outsmarting influenza: mechanism-based covalent neuraminidase inhibitors
T. Wennekes, Wageningen University/NL; S. Withers, University of British Columbia, Vancouver/CDN
P 04 Impact of a weak protein-ganglioside interaction on the structure of a model lipid membrane exposed to changing electric fields
I. Brand, University of Oldenburg/D; S. Kelm, University of Bremen/D
P 05 Cascade reactions for the synthesis of novel
Poly-N-acetyllactosamine (Poly-LacNAc) glycans

C.E. Kupper, R.R. Rosencrantz, C. Rech, L. Elling, RWTH Aachen University/D
P 06 Modification of cyclic peptides from entomopathogenic bacteria for functional analysis
F.I. Nollmann, H.B. Bode, University of Frankfurt/D
P 07 Induction of tumor cell death by survivin nuclear export inhibitors
V. Fetz, D. Docter, University Medical Center Mainz/D; R. Hecht, S.K. Knauer, University Duisburg-Essen, Essen/D; R.H. Stauber, University Medical Center Mainz/D
P 08 A large synthetic peptide and phosphopeptide reference library for mass spectrometry-based proteomics
B. Kuster, G. Médard, TU München, Freising/D
P 09 TFF2 is a lectin stabilizing the laminated gastric mucus
R. Stürmer, University of Magdeburg/D; St. Müller, University of Cologne/D; T. Fu, University of Magdeburg/D; F.-G. Hanisch, University of Cologne/D; W. Hoffmann, University of Magdeburg/D
P 10 Synthetic access to novel labeled microcystin derivatives
I. Zemskov, W. Wittmann, Universität Konstanz/D
P 11 European Lead Factory - game changing for innovative medicine
D. Tzalis, Taros Chemicals GmbH & Co. KG, Dortmund/D
P 12 Development of anti-arrhythmia compounds directed at RyR2 mediated intracellular Ca2+ leakage and SERCA mediated Ca2+ uptake
L. Kattner, D. Bernardi, E. Rauch, H. Adams, S. Kern, M. Klotz, ENDOTHERM GmbH, Saarbrücken/D; S. Lehnart, Universitätsmedizin Göttingen/D; G.L. Smith, University of Glasgow/UK
P 13 Target fishing by cross-docking: a method to explain side effects of drugs
H. Patel, B. Grüning, X. Lucas, I. Merfort, S. Günther, University of Freiburg/D
P 14 Investigation of of dihydropyridines for intercepting the early secretory pathway
A. Krämer, T. Mentrup, Leibniz Institute for Age Research - Fritz Lipmann Institute, Jena/D; B. Kleizen, Bijvoet Center for Biomolecular Research, Utrecht/NL; E. Rivera-Milla, D. Reichenbach, Leibniz Institute for Age Research - Fritz Lipmann Institute, Jena/D; C. Enzensperger, Bijvoet Center for Biomolecular Research, Utrecht/NL; R. Nohl, E. Täuscher, H. Görls, University of Jena/D; A. Ploubidou, C. Englert, Leibniz Institute for Age Research - Fritz Lipmann Institute, Jena/D; O. Werz, University of Jena, Jena/D; H.-D. Arndt, University of Jena/D; C. Kaether, Leibniz Institute for Age Research - Fritz Lipmann Institute, Jena/D
P 15 Systematic analysis of epigenetic modifications using peptide microarrays
A. Masch, A. Rohe, M. Schmidt, W. Sippl, University of Halle-Wittenberg, Halle/D; V. Schoeppler, J. Jansong, N. Pawlowski, U. Reimer, JPT Peptide Technologies GmbH, Berlin/D; M. Schutkowski, University of Halle-Wittenberg, Halle/D
P 16 Sulfur heterocycles
A.G. Pandey, University of Uppsalla/S; C. Bolm, RWTH Aachen University/D; O. Garcia, University of Münster/D; M.J. McGrath, WTC, Brisbane/AUS
P 17 Synthesis of novel colchicine derivatives and B-ring modified analogues
P. Thomopoulou, H.-G. Schmalz, University of Cologne/D
P 18 Development of novel (E)-1,2,3-triaryl-2-propen-1-one derivatives acting on breast cancer cells via dual inhibitory mechanisms
S. Arfaei, A. Zarghi, Shahid Beheshti University of Medical Sciences, Tehran/IR; M.J. Meegan, Trinity College Dublin/IRL
P 19 Syntheses and biological investigations of conformationally restricted scaffolds for modulation/inhibition of protein-protein-interactions
S. Dohmen, C. Reuter, A. Soicke, V. Hack, H.-G. Schmalz, University of Cologne/D; R. Kühne, R. Opitz, Leibniz-Institut für Molekulare Pharmakologie (FMP), Berlin/D
P 20 Scorpion shaped glycogen synthase kinase-3 inhibitors versus Tivantinib
T. Neumann, F. Lo Monte, T. Kramer, B. Schmidt, TU Darmstadt/D
P 21 Discovering novel substrates for human Sirtuin5
C. Roessler, T. Nowak, University of Halle-Wittenberg, Halle/D; M. Pannek, University of Bayreuth/D; M. Scharfe, W. Sippl, University of Halle-Wittenberg, Halle/D; C. Steegborn, University of Bayreuth/D; M. Schutkowski, University of Halle-Wittenberg, Halle/D
P 22 Generation of homogeneous glycosylated Erythropoietin with non-natural amino acids
K. Streichert, M. Rubini, University of Konstanz/D
P 23 Engineering of human Erythropoietin with fluorinated amino acids
E. Hoffmann, M. Rubini, University of Konstanz/D
P 24 Identification of irreversible inhibitors of viral proteases via dynamic fragment ligation
D. Becker, C. Arkona, FU Berlin/D; R. Hilgenfeld, University of Lübeck/D; J. Rademann, FU Berlin/D
P 25 Reactive phosphotyrosine mimetics
S. Wagner, FU Berlin/D; A. Horatscheck, Leibniz-Institut für Molekulare Pharmakologie (FMP), Berlin/D; J. Rademann, FU Berlin/D
P 26 Sc(III) catalyzed regioselective multi-functionalization of polysubstituted 3-hydroxylpyridine methyl esters
K.P. Wojtas, University of Jena/D; J.-Y. Lu, D. Krahn, Max Planck Institute of Molecular Physiology, Dortmund/D; H.-D. Arndt, University of Jena/D
P 27 Structure-activity relationship of adenosine 5'-diphosphoribose at Transient Receptor Potential Melastatin 2 (TRPM2)
C. Moreau, University of Bath/UK; T. Kirchberger, University Medical Center Hamburg-Eppendorf/D; J.M. Swarbrick, S.J. Bartlett, University of Bath/UK; R. Fliegert, T. Yorgan, A. Bauche, A. Harneit, A.H. Guse, University Medical Center Hamburg-Eppendorf/D; B.V.L. Potter, University of Bath/UK
P 28 The challenges of a compound management and screening in the context of a chemical biology platform in academia
E. Specker, M. Neuenschwander, J. von Kries, M. Nazaré, Leibniz Institute of Molecular Pharmacology, Berlin/D
P 29 Tool-Box of glycolipid building blocks: cellular epitope presentation with artificial cell and organelle mimicry for signalling
S. Schiller, N. Mathaiyan, A. Schreiber, M.C. Huber, University of Freiburg/D
Cancelled by the author

P 30 Allosteric regulation of protein kinases of the AGC group: the PIF-pocket as a regulatory and drug target site
R. Biondi, J. Arencibia, H. Zhang, A. Bauer, S. Neimanis, J. Schulze, Frankurt University Hospital/D; H. Stark, D. Odadzic, University of Frankurt/D; W. Fröhner, M. Engel, Saarland University, Saarbrücken/D
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