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PRAXISforum Future Production Concepts in Chemical Industry

Speakers and Moderator

Malcolm Berry, GlaxoSmithKline

Malcolm Berry
Director Chemistry, Second Generation, Continuous Processing, GlaxoSmithKline, United Kingdom

"There are gaps in how industry and regulators think PAT should be used.  One size does not fit all."

Hans-Jürgen Federsel, AstraZeneca

Hans-Jürgen Federsel
Senior Principal Scientist, Chemical Development, AstraZeneca, United Kingdom

"What is the business case for applying flow chemistry/processing in the fine chemicals/pharmaceuticals area? Drivers and blockers for a swift transition to the novel production paradigm offered by flow processing on commercial scale?"

Martijn de Graaff, TNO

Martijn de Graaff
Senior Business Developer, TNO, The Netherlands

"The challenge for flexible plants is not in technology. It is in finding new ways to do business and earn money using this technology."

Sebastian Härtner, Merck

Sebastian Härtner
Senior Development Manager, Merck KGaA, Germany

"How can we downsize well developed down streaming equipment for specialty chemistry in flow and introduce a modular concept for a wide range of parameters!"

Johan ter Harmsel, Zeton B.V.

Johan ter Harmsel
Managing Director, Zeton B.V., The Netherlands

"Modularized Continuous Manufacturing Concepts have a high potential. But is it disruptive enough to change the entire Chemical Industry or will it be a novelty for niche markets only?"

Norbert Kockmann, TU Dortmund

Norbert Kockmann
Lehrstuhl für Apparatedesign, TU Dortmund, Germany

"Downstream process units need robust and versatile equipment. Solids handling is a crucial issue in current process development. Chemists and engineers of various disciplines must work together."

Patrick Löb, Fraunhofer ICT-IMM

Patrick Löb
Deputy Head of Division Energy and Chemical Technology, Fraunhofer ICT-IMM, Germany

"The combination of microreaction technology with a standardized chemical plant infrastructure is an ideal match to attain flexible, fast and mobile production. Further, additional potential lies in an integrated approach for process automatization form lab to pilot and production scale."

Stefan Lier, Ruhr University Bochum

Stefan Lier
Head of Group Transformable Production and Logistic Concepts, Ruhr University Bochum, Germany

"There are still many challenges which have to be tackled before new production concepts are implemented in an operational environment in many places. Firstly, we need a development of modular apparatuses especially within separation technologies, secondly, logistics and operation concepts have to be adjusted and, thirdly, automation technologies and assistant systems have to support plug and produce concepts."

Andreas Müller, hte

Andreas Müller
Leader Project Management, hte, Germany

"Long research periods will throttle a new market introduction campaign and negatively impact later market penetration. We will need new strategies for speeding R&D campaigns on an increasingly competitive market. Research represents only one first step in product commercialization. Here also a proper research migration strategy, which considers later production aspects as well, will be essential. A high level of automation in R&D will not always guarantee best usage of invests, a proper automation migration strategy helps to adapt investments to a reasonable level."

Peter Pöchlauer, Patheon

Peter Pöchlauer
Innovation Manager, Patheon, Austria

"We need considerable improvements in pharmaceutical manufacturing to ensure our supply with affordable high-quality medicines."

Dirk Schmalz, Merck KGaA

Dirk Schmalz
Head of Process Technologies - Engineering, Merck KGaA, Germany

Joint stetement with Frank Stenger, Evonik:
"Industry 4.0 will further trigger the trend to new business and production concepts within chemical industry. The necessary change to modularized production concepts within the chemical industry can only be successful in strong cooperation with the adjacent industry and suppliers."

Armin Schweiger, INVITE

Armin Schweiger
CEO, INVITE, Germany
"The key to success for modular plants is the definition and common agreement of design standards."

Frank Stenger, Evonik

Frank Stenger
Group Head Chemical Reaction Technology, Evonik, Germany

Joint statement with Dirk Schmalz, Merck KGaA:
"Industry 4.0 will further trigger the trend to new business and production concepts within chemical industry. The necessary change to modularized production concepts within the chemical industry can only be successful in strong cooperation with the adjacent industry and suppliers."

Rebecca Vangenechten, Siemens

Rebecca Vangenechten

Global Account Manager, Siemens AG, Germany

"The Pharmaceutical and Chemical process Industries are challenged with market dynamics that require increased flexibility, faster market readiness and improved productivity, all under the highest quality conditions assuring patient safety. By introducing digitalization, one can achieve Integrated Engineering and Integrated Operations, which will able the industry to respond more agile to their customer requirements by an increase of in speed (time to market), flexibility and efficiency."

Mathias Vornefeld, CINC

Mathias Vornefeld
CEO, CINC, Germany
"Continuous processes are in general more economical and more ecological compared to batch processes so please CINC continuously to optimize."

Charlotte Wiles, Chemtrix

Charlotte Wiles
CEO, Chemtrix, United Kingdom

"What methods are people using to quantify the commercial benefits of continuous flow technology? What is considered to be a reasonable timeframe for ROI for a new technology?"

Alexis Bazzanella, DECHEMA e.V.

The Moderator:

Alexis Bazzanella
Head of Research and Project Coordination, DECHEMA e.V., Germany
"Joint collaboration of the large owner-operators, equipment manufacturers and engineering contractors towards a common standardized modular plant concept is a prerequisite for the success of modular production in chemical industry."

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