3D Cell Culture 2018

Programme

The conference will highlight latest developments in the 3D cell culture field: Advanced cell culture models for understanding of diseases and substance testing. Success stories: clinical and industrial applications of 3D cell culture systems. Innovative enabling technologies.

 

You are still cordially invited to contribute to the programme of 3D Cell Culture 2018.
The Call for Papers is open for Late Posters, deadline for submissions is 30 April 2018.
 

   PROGRAMME - Tuesday, 05 June 2018   

PROGRAMME - Wednesday, 06 June 2018

 PROGRAMME - Thursday, 07 June 2018  

PROGRAMME - POSTERs, 05 - 07 June 2018

(Programme subject to change)

 

Tuesday, 05 June 2018

09:30

Registration

10:30 Welcome Address
 
Effects of Microenvironment

Chair: H. Hauser¹; ¹ Helmholtz Centre for Infection Research, Braunschweig/D

10:35
Keynote

Synthetic matrices for organoids
M. Lutolf¹; ¹ Ecole Polytechnique Fédérale de Lausanne, Lausanne/CH

11:20 Macromolecular crowding in 2D and 3D culture systems: creating of cell and stem cell specific microenvironments
M. Raghunath¹; N. Kohli¹; ¹ Zurich University of Applied Sciences, ICBT, Wädenswil/CH
11:40 Redefining cell culture environment with combinatorial biomatrices
A. Thomas¹; ¹ B CUBE Center for Molecular Bioengineering, Center for Molecular and Cellular Bioengineering - TU Dresden,, Dresden/D
12:00 iPSC-derived neurospheroids recapitulate development and pathological signatures of brain microenvironment
A. Terrasso¹; D. Simão¹; N. Bayó-Puxan²; F. Arez¹; M. Silva¹; M. Sousa¹; S. Creysells³; P. Gomes-Alves¹; N. Raimundo⁴; E. Kremer³; P. Alves¹; C. Brito¹;
¹ iBET, Instituto de Biologia Experimental e Tecnológica, Oeiras, Portugal; Instituto de Tecnologia Química e Biológica António Xavier, Universidede Nova de Lisboa, Oeiras, Portugal;, Oeiras/P; ² Institute of Biomedicine of the University of Barcelona (IBUB); Institut de Génétique Moléculaire de Montpellier, CNRS UMR 5535; Université de Montpellier, Barcelona; Montpellier/E; ³ Institut de Génétique Moléculaire de Montpellier, CNRS UMR 5535; Université de Montpellier, Montpellier/F; ⁴ Universitätsmedizin Göttingen, Institut für Zellbiochemie, Göttingen/D
12:20 Expansion of mouse pancreatic organoids in a chemically defined three-dimensional matrix
N. Rischert¹; H. Wurst¹; T. Moreth²; L. Hof²; E. Stelzer²; M. Huch³; F. Pampaloni²; B. Angres¹; ¹ Cellendes GmbH, Reutlingen/D; ² Goethe-Universität Frankfurt am Main, Frankfurt am Main/D; ³ University of Cambridge, Cambridge/UK
12:40 Lunch Break / Posters / Exhibition
 
Imaging and Analytics

Chair: R. Pörtner¹; ¹ Hamburg University of Technology/D

 14:00
Keynote

Observing three-dimensional biological specimens with
light sheet-based fluorescence microscopy (LSFM)

E. H. K. Stelzer¹; ¹ Buchmann Institute for Molecular Life Sciences - Goethe University Frankfurt am Main, Frankfurt am Main/D

 14:45 Image-based quantification of immunotherapies effects in 3D environment
K. Yan¹; L. Daszkiewicz¹; L. Price¹; ¹ OcellO B.V., Leiden/NL
 15:05 3D culture models for investigaing recruitment of stem cells to the vascular niche
Y. Atlas¹; C. Gorin2; C. Chaussain2; S. Germain1;  L. Muller¹;
¹ CIRB, Collège de France, Paris/F; 2 Decartes University, Dental School, Paris/F
 15:25 STATARRAYS©: microcavity arrays as a useful tool to detect single cell migration in a 4D co-culture model of human bone marrow
E. Gottwald¹; S. Giselbrecht¹; R. Truckenmüller¹; V. Colditz²; C. Nies²;
¹ 300MICRONS GmbH, Karlsruhe/D; ² Karlsruhe Institute of Technology (KIT), Karlsruhe/D
 15:45  Coffee Break / Posters / Exhibition
 
Predictive Model Systems

Chair: T. May¹; ¹InSCREENeX GmbH, Braunschweig/D

16:15
Keynote

3D human liver spheroid systems for analyses of liver diseases, liver function, drug metabolism and toxicity
M. Ingelman-Sundberg¹; ¹ Karolinska Institutet, Stockholm/S

 17:00 Novel predictive 3D cultivation models for validating small molecules against KSHV infection
T. Dubich¹; C. Lipps¹; T. May²; M. Stadler¹; T. Schulz³; D. Wirth¹;
¹ Helmholtz Centre for Infection Research, Braunschweig/D; ² InSCREENeX GmbH, Braunschweig/D; ³ Institute of Virology, Hannover Medical School, Hannover/D
 17:20 Three-dimensional tumor cell growth stimulates autophagic flux and recapitulates chemotherapy resistance
C. Bingel¹; E. Koeneke¹; J. Ridinger¹; A. Bittmann¹; M. Sill²; H. Peterziel¹; J. Wrobel¹; I. Rettig¹; T. Milde¹; U. Fernekorn³; F. Weise³; A. Schober³; O. Witt¹; I. Oehme⁴; ¹ CCU Pediatric Oncology, German Cancer Research Center (DKFZ), Heidelberg/D; ² German Cancer Research Center DKFZ), Heidelberg/D; ³ Dpt of Nano-Biosystem Technology, TU Ilmenau, Ilmenau/D; ⁴ DKFZ Heidelberg, Heidelberg/D
 17:40
Keynote

Synthetic Biology-Inspired Treatment Strategies of the Future

M. Fussenegger¹; ¹ ETH Zurich, Zurich/CH
18:25

Poster Session / Poster Party (18:25 - 21:00)

18:30

Section Member Assembly (Room K3+K4 / 18:30 - 19:30)
DECHEMA Working Groups Cell Culture Technology and Medical Biotechnology

 

 

Wednesday, 06 June 2018

08:30

Registration

 
Advanced Models - Skin

Chair: U. Marx¹; ¹TissUse GmbH, Berlin/D

09:00
Keynote
In vitro skin models for clinical research and transplantation
S. Gibbs¹; ¹ VU University Medical Center Amsterdam, Amsterdam/NL
09:45 Towards an immunocompetent skin model to study and develop materials for wound healing
C. Griffoni¹; B. Sentürk¹; M. Rottmar¹; K. Maniura¹; ¹ Empa - Swiss Federal Laboratories for Materials Science and Technology, St Gallen/CH
10:05 vascSkin-on-a-chip: combination strategies of human skin-equivalents
and vasculature

K. Schimek¹; A. Thomas²; T. Hasenberg³; G. Giese⁴; U. Marx³; R. Lauster⁴; G. Lindner⁴; ¹ Technische Universität Berlin, FG Medizinische Biotechnologie, Berlin/D; ² Cellbricks GmbH, Berlin/D; ³ TissUse GmbH, Berlin/D; ⁴ Technische Universität Berlin, Berlin/D
10:25 MUG-Mel2, a novel highly pigmented and well characterized NRAS mutated human melanoma cell line in 3D culture
B. Rinner¹; G. Gandolfi²; K. Meditz¹; M. Frisch¹; K. Wagner¹; A. Ciarrocchi²; F. Torricelli²; R. Koivuniemi³; J. Niklander³; B. Liegl-Atzwnager¹; B. Lohberger¹; E. Heitzer¹; N. Ghaffari-Tabrizi-Wizsy¹; D. Zweytick¹; I. Zalaudek¹
¹ Medical University of Graz, Graz/A; ² Laboratorio di Ricerca Traslazionale Arcispedale S. Maria Nuova - IRCCS, Reggio Emilia/I; ³ University of Helsinki, Helsinki/FIN
10:45 Coffee Break / Posters / Exhibition
 
Advanced Models - Vascularization, Muscle

Chair: H. Ruffner¹; ¹Novartis Institutes for BioMedical Research, Basel/CH

11:15 Pre-vascularized cell cultivation system to generate perfused 3D co-culture models
I. Prade¹; M. Busek²; M. Wiele¹; F. Sonntag²; M. Meyer¹; ¹ FILK gGmbH, Freiberg/D; ² Fraunhofer-Institut für Werkstoff- und Strahltechnik, Dresden/D 
11:35 Generation of 3D human cardiac macrotissues with tissue-like functionality
M. Valls-Margarit¹; O. Iglesias-García²; C. Di Guglielmo²; L. Sarlabous¹; R. Paoli¹; J. Comelles¹; D. Blanco-Almazán¹; S. Jiménez-Delgado²; O. Castillo-Fernández³; J. Samitier¹; R. Jané¹; E. Martínez¹; Á. Raya²; ¹ Institute for Bioengineering of Catalonia, Barcelona/E; ² Center of Regenerative Medicine in Barcelona, Barcelona/E; ³ Institute of Microelectronics of Barcelona, Bellaterra/E
11:55
Keynote

Advanced induced pluripotent stem cell (iPSC) screens
M. Müller¹; ¹ Novartis Institutes for BioMedical Research, Basel/CH

12:40

Lunch / Posters / Exhibition

 
From Models to High Throughput

Chair: J. Kelm¹; ¹ Competence Centre TEDD, Wädenswil/CH

14:00 Merging high-content and high-throughput screening: Microphysiological Organ-on-a-Chip systems featuring complex human tissues with physiological structure and function
P. Loskill¹; ¹ Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB, Stuttgart/D
14:20 Modification of a standardized 3D in vitro tumor-stroma model for high throughput screening of candidates of new tumor therapeutica
S. Hensler¹; C. Kühlbach¹; M. Mueller¹; ¹ HFU Hochschule Furtwangen, Villingen-Schwenningen/D
 14:40 Development of a matrix-based technology platform for the high throughput analysis of 3D cell cultures
M. Rimann¹; A. Picenoni¹; E. Bono¹; E. Felley-Bosco²; C. Hund³; R. Pellaux³; A. Meyer³; ¹ Zurich University of Applied Sciences, ICBT, Waedenswil/CH; ² Laboratory of Molecular Oncology, Zurich University Hospital, Zurich/CH; ³ FGen GmbH, Basel/CH
 15:00 Magnetic 3D Bioprinting for High-Throughput Compound Screening and Translational Applications
G. Souza¹; G. Bartholomeusz²
¹ The University of Texas Health Science Center, Houston/USA; ² UT MD Anderson Cancer Center, Houston/USA
15:20 Simple and robust microfluidic platform for spheroid culturing in a high-throughput manner
J. Kim¹; H. Choi²
¹ Daegu Gyeongbuk Institute of Science and Technology, Deagu/ROK; ² Daegu Gyeongbuk Institute of Science and Technology, Daegu/ROK
15:40 Microtissues meet microfluidics – next generation microphysiological tilting system
K. Renggli¹; C. Lohasz¹; S. Bürgel¹; D. Fluri²; A. Hierlemann¹; O. Frey²
¹ ETH Zürich, Basel/CH; ² Insphero AG, Schlieren/CH
16:00

Coffee Break / Posters / Exhibition

 
From Models to Clinical and Industrial Solutions

Chair: T. Noll¹; ¹ University of Bielefeld/D

16:30
Keynote
The application of microphysiological systems in drug discovery using case studies from safety and efficacy questions
L. Ewart¹; ¹ AstraZeneca, Cambridge/UK
17:15 Bringing 3D Tumor Models to the clinic
– predictive value for personalized medicine

K. Halfter¹; B. Mayer²; ¹ SpheroTec GmbH, Munich/D; ² Hospital of the LMU Munich, Munich/D
17:35 Single-donor iPSC derived Multi-Organ-Chips
A. Ramme¹; L. Koenig¹; D. Faust¹; A. Krebs¹; T. Hasenberg¹; E. Dehne¹; U. Marx¹;
¹ TissUse GmbH, Berlin/D
17:55 Rethinking Drug Development - 3D Disease Models for Advanced Preclinical Drug Evaluation
M. Schäfer-Korting¹; S. Hedtrich¹; V. Kral¹; G. Weindl¹; J. Plendl¹; C. Thöne-Reineke¹; B. Kleuser²; R. Preissner³; A. Pries³; A. Volkamer³; R. Lauster⁴; A. Luch⁵; G. Schönfelder⁵; M. Weber⁶; ¹ Freie Universität Berlin, Berlin/D; ² Potsdam University, Potsdam/D; ³ Charité Universitätsmedizin Berlin, Berlin/D; ⁴ Technische Universität Berlin, Berlin/D; ⁵ Federal Institute for Risk Assessment, Berlin/D; ⁶ Zuse Institute Berlin, Berlin/D
18:15 End of Lecture Programme
19:30
Conference Dinner(click BUTTON for DETAILS)
Schlossbergrestaurant Dattler
Am Schlossberg 1
79104 Freiburg

 

Thursday, 07 June 2018

08:30

Registration

 
Advanced Models - From Liver to LUNG

Chair: M. Rimann¹; ¹ Zurich University of Applied Sciences, Wädenswil/CH

09:00 Metabolic cross talk between human pancreatic islet and liver spheroids in a microphysiological system - Towards a novel human ex vivo model of Type 2 Diabetes
S. Bauer¹; C. Wennberg Huldt²; K. Kanebratt²; I. Durieux¹; D. Gunne¹; S. Andersson²; L. Ewart³; W. Haynes²; I. Maschmeyer¹; A. Winter¹; C. Ämmälä⁴; U. Marx¹; T. Andersson⁴; ¹ TissUse GmbH, Berlin/D; ² AstraZeneca, Mölndal/S; ³ AstraZeneca, Cambridge/UK; ⁴ AstraZeneca, Mölndal/D
09:20 Mimicking human physiology at Transwell-based barrier models of the proximal tubulus – The ZEBRA-Chip
F. Schmieder¹; D. Förster²; M. Hempel¹; J. Sradnick²; B. Hohenstein²; F. Sonntag¹;
¹ Fraunhofer Institute for Material and Beam Technology IWS, Dresden/D; ² Division of Nephrology, Department of Internal Medicine III, University Hospital Carl Gustav Carus Dresden, Dresden/D
09:40

Human and mouse intestinal organoids as model system for studying

drug transport
T. Zietek¹; ;E. Rath²; F. Reichart³; H. Kessler³; G. Ceyhan⁴, I. Demir⁴, H. Daniel¹;

¹ Technische Universität München, Freising/D; ²TUM ZIEL Institute for Food & Health, Freising/D; ³TUM Institute for Advanced Study, Garching/D; ⁴Dept. of Surgery, Klinikum rechts der Isar, München, Germany

10:00 Microstructured 3D model of small intestine epithelium: breaking the mold
M. García-Díaz¹; A. G. Castaño¹; G. Altay¹; N. Torras¹; R. Martin-Venegas²; R. Ferrer¹; E. Martínez¹; ¹ Institute for Bioengineering of Catalonia, Barcelona/E; ² Universitat de Barcelona, Barcelona/E
10:20 Long-term culture of rat Precision-Cut Lung Slices using Lab-on-Chip technology as an ex vivo system with prolonged viability
S. Konzok¹; S. Dehmel¹; V. Neuhaus¹; J. Labisch¹; S. Grünzner²; F. Sonntag²; A. Braun¹; K. Sewald¹; ¹ Fraunhofer Institute for Toxicology and Experimental Medicine ITEM, Hannover/D; ² Fraunhofer Institute for Material and Beam Technology IWS / Dresden University of Technology, Dresden/D
10:40

Coffee Break / Posters / Exhibition

 
Safety and Toxicity Testing

Chair: U. Marx¹; ¹ TissUse GmbH, Berlin/D

11:15
Keynote

Advanced cell models, organs on a chip & microphysiological systems in drug safety assessment: the need, the vision – and challenges to overcome
A. Roth¹; ¹ F. Hoffmann-La Roche Ltd., Basel/CH

12:00 A Novel 3D Human Liver Fibrosis Model for Anti-fibrotic Drug Discovery and Safety Testing
P. Guye¹, S. Messner¹; ¹ Insphero AG, Schlieren/CH
12:20 Bioprinted kidney model to assess nephrotoxicity
M. Nosswitz¹; M. Rimann²; N. Hernando³; C. Wagner³; U. Graf-Hausner¹; M. Raghunath¹; ¹ Zurich University of Applied Sciences, ICBT, Waedenswil/CH; ² Zurich University of Applied Sciences, ICBT, Wädenswil/CH; ³ University of Zurich, Zurich/CH
12:40 Microfluidic Platform for Advanced Embryotoxicity Testing in vitro
J. Boos¹; A. Michlmayr¹; K. Renggli¹; O. Frey²; A. Hierlemann³; ¹ ETH Zürich, D-BSSE Basel, Basel/CH; ² Insphero AG, Schlieren/CH; ³ ETH Zürich, D-BSSE Basel, Basel/CH
13:00
Closing remarks
13:05

Lunch / Posters / Exhibition

14:15 End of the Conference

 

 

Poster Programme, 05 - 07 June 2018

Topic
1.1 Advanced cell culture models

P1.1.01

Advanced physiologically relevant 3D models for pre-clinical screening
D. Sabino¹; I. Fixe¹; A. Foucher¹; F. Carpentier¹; M. Rochet¹; I. Topin¹; E. Mennesson¹; N. Normand¹; ¹ tebu-bio, Le Perray en Yvelines/F

P1.1.02

Evaluation of EGFR induced on-target and target-mediated adverse effects in a microfluidic 3D human lung tumour – full thickness skin co-culture model
J. Hübner¹; M. Raschke²; I. Rütschle¹; S. Schnurre²; S. Gräßle¹; I. Maschmeyer¹; U. Marx¹; T. Steger-Hartmann²; ¹ TissUse GmbH, Berlin/D; ² Bayer AG, Berlin/D

P1.1.03

A 3D High-Content Screening assay as model system for polycystic kidney disease
H. Bange¹; T. Booij²; W. Leonhard³; K. Yan¹; D. Peters³; L. Price¹; ¹ OcellO B.V., Leiden/NL; ² LACDR, Leiden University, Leiden/NL; ³ Leiden University Medical Centre, Leiden/NL

P1.1.04

Parallelized Heart-on-a-chip with integrated Force Sensing incorporating human iPS-derived cardiac microtissues
C. Probst¹; O. Schneider¹; S. Fuchs¹; P. Loskill¹; ¹ Fraunhofer IGB, Stuttgart/D

P1.1.05

Establishment of an advanced in vitro model to study nanomaterial-intestinal barrier interactions
C. Hempt¹; C. Hirsch¹; M. Kucki¹; P. Wick¹; T. Buerki-Thurnherr¹; ¹ Empa - Swiss Federal Laboratories for Materials Science and Technology, St.Gallen/CH

P1.1.06

The Ocular DynaMiTES – A dynamic microfluidic in vitro system with improved predictability of ocular drug absorption
N. Beißner¹; K. Mattern²; A. Dietzel²; S. Reichl¹; ¹ TU Braunschweig/ Institut für Pharmazeutische Technologie, Braunschweig/D; ² TU Braunschweig/ Institut für Mikrotechnik, Braunschweig/D

P1.1.07

Cell Processing in Microreactors: Real-time Monitoring of Cell Metabolism Using Sensor Particles and Surface Based, Gentle Cell Detachment
K. Uhlig¹; C. Gehre²; S. Prill²; M. Stahl²; C. Duschl²; E. Schmälzlin³; L. Dähne⁴; T. Hellweg⁵; ¹ Fraunhofer-Institut für Zelltherapie und Immunologie IZI, Potsdam/D; ² Fraunhofer-Institute for Cell Therapy and Immunology, Potsdam/D; ³ Colibri Photonics GmbH, Potsdam/D; ⁴ Surflay Nanotec GmbH, Berlin/D; ⁵ Bielefeld University, Bielefeld/D

P1.1.08

Evaluation of a Novel Cell Culture Platform with Various Barrier Forming Cells for Dynamic Cultivation
S. Hinkel¹; K. Mattern²; A. Dietzel²; S. Reichl¹; C. Müller-Goymann¹;
¹ TU Braunschweig/ Institut für Pharmazeutische Technologie, Braunschweig/D; ² TU Braunschweig/ Institut für Mikrotechnik, Braunschweig/D

P1.1.09

Ready-to-use 3D spheroid culture as a standard tool
I. Prieto¹; ¹ StemTek Therapeutics, DERIO/E

P1.1.10

Dual targeting of prognostic biomarkers in the 3D microtumor model of advanced colorectal cancer
C. Ilmberger¹; O. Hoffmann¹; J. Gülden²; T. Bühl²; J. Werner²; B. Mayer²; ¹ SpheroTec GmbH, Munich/D; ² Hospital of the LMU Munich, Munich/D

P1.1.11

Permeation Measurement for 3D Skin Culture in a Membrane Insert System
H. Hsu¹; K. Schimek²; U. Marx³; R. Pörter⁴; ¹ Technische Universität Hamburg-Harburg, Hamburg/D; ² Department Medical Biotechnology of Biotechnology, Technische Universität Berlin, Berlin/D; ³ TissUse GmbH - TU Berlin, Berlin/D; ⁴ Institute of Bioprocess- and Biosystems Engineering, Hamburg University of Technology, Hamburg/D

P1.1.12

Preservation of tumor architecture and heterogeneity in long-term cultures of patient-derived explants
S. Abreu¹; S. da Mata²; F. Silva³; M. Teixeira¹; T. Franchi Mendes¹; R. Fonseca⁴; B. Filipe²; S. Morgado²; I. Francisco²; M. Mesquita²; C. Albuquerque²; J. Serpa⁵; P. Chaves²; I. Rosa²; A. Felix⁵; E. R. Boghaert⁶; V. E. Santo¹; C. Brito¹; ¹ iBET/ITQB-NOVA, Oeiras/P; ² IPOLFG, Lisboa/P; ³ CEDOC-FCM-NOVA, Lisboa/P; ⁴ IPOLFG and FMUL, Lisboa/P; ⁵ IPOLFG and CEDOC-FCM-NOVA, Lisboa/P; ⁶ AbbVie, Chicago/USA

P1.1.13 Establishment of a murine intestinal tissue model based on immortalized primary epithelial cells
C. Fey¹; T. Truschel²; M. Schweinlin¹; H. Walles³; T. May²; M. Metzger³
¹ Department of Tissue Engineering and Regenerative Medicine (TERM), University Hospital Würzburg, Würzburg/D; ² InSCREENeX GmbH, Braunschweig/D; ³ Translational Center Würzburg “Regenerative Therapies for Oncology and Musculoskeletal Diseases” (TZKME), Würzburg branch of the Fraunhofer Institute of Silicate Research (ISC), Würzburg/D
P1.1.14 Development of a human epidermal burn wound model
V. Schneider¹; ¹ Uniklinik Würzburg, Würzburg/D
P1.1.15 Initial screening of novel copolymer micelles for biocompatibility and effects on cell motility
Y. Yordanov¹; D. Aluani¹; B. Tzankov¹; V. Tzankova¹; R. Kalinova²; I. Dimitrov³; V. Bankova⁴; M. Popova⁴; B. Trusheva⁴; K. Yoncheva¹
¹ Faculty of Pharmacy, Medical University of Sofia, Sofia/BG; ² Institute of Polymers, Bulgarian Academy of Sciences, Sliven/BG; ³ Institute of Polymers, Bulgarian Academy of Sciences, Sofia/BG; ⁴ Institute of Organic Chemistry with Center for Phytochemistry, Bulgarian Academy of Sciences, Sofia/BG
P1.1.16 An injectable hybrid hydrogel for tissue engineering applications
R. Wittig¹; B. Baumann²; M. Lindén²
¹ Institute for Laser Technologies in Medicine & Metrology (ILM) at Ulm University, Ulm/D; ² Institute for Inorganic Chemistry II, Ulm University, Ulm/D
P1.1.17 A tissue engineered Full Thickness Skin Equivalent based on a non-contracting, biophysical optimised collagen type-I hydrogel
P. Fey¹; C. Reuter²; T. Finger¹; M. Engstler²; H. Walles³; F. Groeber-Becker¹
¹ Fraunhofer ISC - Translationszentrum für Regenerative Therapien TLZ-RT, Würzburg/D; ² Julius-Maximilians Universität Würzburg, Würzburg/D; ³ Universitätsklinikum Würzburg, Würzburg/D
P1.1.18 Cell on cell – functionally immortalized smooth muscle cells as building blocks for 3D tissues
A. Bleisch¹; ¹ InSCREENeX GmbH, Braunschweig/D
P1.1.19 Evaluation of local inflammatory reactions following subcutaneous injection of a pro-inflammatory cocktail in a fully human ex vivo skin model
C. Jardet¹; E. Pagès¹; E. Raude²; F. Seeliger³; L. Brandén³; E. Braun¹; M. Ingeslten³; P. Descargues⁴
¹ GENOSKIN SAS, Toulouse/F; ² LAAS CNRS, Toulouse/F; ³ Drug Safety and Metabolism, iMED Biotech Unit, Astra Zeneca, Gothenburg/S; ⁴ Genoskin Inc., Boston (MA)/USA
P1.1.20 A microchip array-based 3D culture system for the in vitro differentiation
of osteoblasts

W. Zhang¹; P. Tomakidi²; T. Steinberg²; R. Kohal³; E. Gottwald⁴; B. Altmann¹
¹ G.E.R.N., Department of Oral and Maxillofacial Surgery, University Medical Center Freiburg, Freiburg im Breisgau/D; ² Department of Oral Biotechnology, University Medical Center Freiburg, Freiburg im Breisgau/D; ³ Department of Prosthetic Dentistry, University Medical Center Freiburg, Freiburg im Breisgau/D; ⁴ 300MICRONS GmbH, Karlsruhe/D
P1.1.21 Automating 3D cell culture using a wood-derived hydrogel
L. Paasonen¹; ¹ UPM-Kymmene Corporation, Helsini/FIN
P1.1.22 Combining pluripotent stem cell-derived models of the blood-brain barrier with Multi-Organ-Chip systems
L. Koenig¹; A. Ramme¹; D. Faust¹; E. Dehne¹; U. Marx¹; ¹ TissUse GmbH, Berlin/D
P1.1.23 Microspheres-based scaffolds from poly(3-hydroxybutyrate) for 3D cell growth
D. Chesnokova¹; I. Zharkova¹; A. Bonartsev¹; V. Voinova¹
¹ Lomonosov Moscow State University, Faculty of Biology, Moscow/RUS
P1.1.24 In vitro 3D bladder cancer model using PDX-derived cells
R. Amaral¹; A. Ma²; H. Zhang²; K. Swiech¹; C. Pan²
¹ University of Sao Paulo, Ribeirao Preto/BR; ² University of California Davis, Sacramento/USA
   
Topic
1.2 Innovative disease models

P1.2.01

A tissue engineering approach to model Primary Ciliary Dyskinesia
N. Lodes¹; H. Walles²; S. Hackenberg³; H. Hebestreit⁴; M. Steinke²; ¹ University Hospital Würzburg, Chair of Tissue Engineering and Regenerative Medicine, Würzburg/D; ² University Hospital Würzburg, Chair of Tissue Engineering and Regenerative Medicine; Fraunhofer Institute for Silicate Research, Translational Center Regenerative Therapies, Würzburg/D; ³ University Hospital Würzburg, Department of Otorhinolaryngology, Plastic, Aesthetic and Reconstructive Head and Neck, Würzburg/D; ⁴ University Hospital Würzburg, Department of Paediatrics, Würzburg/D

P1.2.02

Characterisation of Bordetella pertussis virulence mechanisms using engineered human airway tissue models
D. Kessie¹; ¹ Julius-Maximilians Universität Würzburg, Würzburg/D

P1.2.03 Establishment and initial characterization of a simple 3D organotypic wound healing model
S. Hensler¹; C. Kühlbach²; J. Parente³; S. Krueger-Ziolek⁴; K. Moeller⁴; M. Mueller²
¹ HS Furtwangen, Villingen-Schwenningen/D; ² Molecular Cell Biology Lab, Institute of Technical Medicine, HFU Furtwangen, Villingen-Schwenningen/D; ³ Institute of Technical Medicine, HFU Furtwangen University, Villingen-SChwenningen/D; ⁴ Institute of Technical Medicine, HFU Furtwangen University, Villingen-Schwenningen/D
P1.2.04 Novel 3D tumour models with stromal components to evaluate the efficacy of immunotherapy with gene-engineered ROR1-specific CAR T cells
J. Kühnemundt¹
¹ University Hospital Würzburg, Department of Tissue Engineering & Regenerative Medicine, Würzburg, Germany;, Würzburg/D
P1.2.05 Evaluation of pharmacological responses in InflammaSkin®, a fully human full-thickness ex vivo skin model reproducing key features of psoriatic lesions
P. Lovato¹; C. Jardet²; E. PAGES²; A. David²; E. Braun²; H. Norsgaard¹; P. Descargues³
¹ LEO Pharma, Ballerup/DK; ² GENOSKIN SAS, Toulouse/F; ³ Genoskin Inc., Boston (MA)/USA
P1.2.06 Generation of human induced pluripotent stem cells (hiPSc)-derived hepatocyte organoids to study liver size control
E. Saponara¹; ¹ Novartis Institutes of Biomedical Research, Basel/CH
   
Topic
1.3 Complex and multi-cell type models

P1.3.01

Using the Real Architecture For 3D Tissue (3D RAFT™) System as a Versatile Tool to Build in vitro Epithelial Barrier Models
T. Willstaedt¹; J. Langer¹; S. Schaepermeier²; S. Buesch²; T. D'Souza¹; L. Hussain¹; J. Schroeder²; ¹ Lonza Walkersville Inc., Walkersville, MD/USA; ² Lonza Cologne GmbH, Cologne/D

P1.3.02

Towards a three-dimensional microfluidic in vitro model to assess efficacy & safety of immune-stimulatory antibody drugs
R. Nudischer¹; C. Bertinetti-Lapatki²; C. Claus³; K. Renggli⁴; C. Lohasz⁴; O. Frey⁵; A. Hierlemann⁴; A. Roth²; ¹ F. Hoffmann-La Roche Ltd., Basel/CH; ² Roche Pharma Research and Early Development, Roche Innovation Center Basel, Basel/CH; ³ Roche Pharma Research and Early Development, Roche Innovation Center Zürich, Schlieren/CH; ⁴ ETH Zürich, D-BSSE Basel, Basel/CH; ⁵ Insphero AG, Schlieren/CH

P1.3.03

MSCs Isolation in 3D cell culture conditions: challenges, modeling and perspectives.
D. Egger¹; M. Kirsch²; T. Scheper²; A. Lavrentieva²; C. Kasper³; ¹ Department of Biotechnology, University of Natural Resources and Life Sciences, Vienna/A; ² Institute of Technical Chemistry, Leibniz University Hanover, Hannover/D; ³ Department of Biotechnology, University of Natural Resources and Life Sciences, Vienna/D

P1.3.04

Retina-on-a-Chip: Merging Organoid and Organ-on-a-Chip technology for complex multi-layer tissue models
J. Chuchuy¹; K. Achberger²; C. Probst¹; J. Haderspeck³; J. Rogal¹; S. Liebau²; P. Loskill¹; ¹ Fraunhofer IGB, Stuttgart/D; ² Eberhard Karls Universität Tübingen, Tübingen/D; ³ Eberhard Karls Universität Tübingen, Stuttgart/D

P1.3.05

WAT-on-a-Chip: Microphysiological systems integrating white adipose tissue
J. Rogal¹; C. Binder²; E. Rubiu²; C. Probst²; K. Schenke-Layland³; P. Loskill¹;
¹ Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB & Eberhard Karls University Tübingen, Stuttgart/D; ² Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB, Stuttgart/D; ³ Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB & Eberhard Karls University Tübingen, Tübingen/D

P1.3.06

High content screening of intestinal organoid cultures to visualize and quantify immune responses
M. Madej¹; B. Herpers¹; L. Salinaro¹; K. Yan¹; L. Daszkiewicz¹; L. Price¹;
¹ OcellO B.V., Leiden/NL

P1.3.07

3D co-cultivation of beta cells and mesenchymal stromal/stem cells for diabetes therapy
F. Petry¹; P. Czermak¹; D. Salzig¹; ¹ Institute of Bioprocess Engineering and Pharmaceutical Technology, University of Applied Sciences Mittelhessen, Gießen/D

P1.3.08

Modeling tumor microenvironment to address the dynamics of tumor, stromal and immune cell interactions
S. Rebelo¹; C. Brito²; D. Simão³
¹ iBET/ITQBAX-UNL, Oeiras/P; ² iBET, Instituto de Biologia Experimental e Tecnológica, Oeiras, Portugal; Instituto de Tecnologia Química e Biológica António Xavier, Universidede Nova de Lisboa, Oeiras, Portugal;, Oeiras/P; ³ iBET, Oeiras/P

P1.3.09 Development of a 3D spheroid SK-MEL-28 tumor model and its characterisation
J. Klicks¹; R. Rudolf¹; M. Hafner¹; ¹ Hochschule Mannheim, Mannheim/D
P1.3.10 Trace Amines and Fatty Acids are Essential Endogenous Signaling Factors for β-Cell Activity and Insulin Secretion
S. Hauke¹; C. Schultz²; ¹ European Molecular Biology Laboratory (EMBL), Heidelberg/D; ² Oregon Health and Science University (OHSU), Portland, OR/USA
P1.3.11 In vitro vascularization of a human bone marrow model.
K. Keskin¹; S. Sieber¹; U. Marx²; R. Lauster¹; M. Rosowski¹
¹ Technische Universität Berlin, FG Medizinische Biotechnologie, Berlin/D; ² TissUse GmbH, Berlin/D
P1.3.12 Development and characterization of PDX-derived 3D tumor microtissues as platform for screening targeted molecular therapeutics
F. Chiovaro¹; N. Buschmann²; I. Agarkova²; A. Maier³; S. Messner²; J. Schueler³; P. Guye²; ¹ InSphero AG, Schlieren/CH; ² Insphero AG, Schlieren/CH; ³ Charles River, Freiburg im Breisgau/D
P1.3.13 Imitation of the long-lived plasma cell survival niche of the human bone marrow in vitro
Z. Uyar¹; S. Sieber¹; U. Marx²; R. Lauster¹; M. Rosowski¹
¹ Technische Universität Berlin
P1.3.14 Development of a Cardiac Organoid Culture System with hiPSC-derived Cardiomyocytes
M. Schulze¹ ; B. Ulmer¹ ; M. Lemoine¹ ; A. Fischer¹ ; T. Eschenhagen¹;
¹ University Medical Center Hamburg-Eppendorf
P1.3.15 Neuronal differentiation of human iPSCs in 3DProSeed hydrogel well plate and establishment of glia co-cultures
S. de Leeuw¹; V. Milleret²; B. Simona³; R. Urbanet²; M. Ehrbar²; C. Tackenberg¹
¹ Institute for Regenerative Medicine, University of Zürich, Schlieren/CH; ² Department of Obstetrics, University hospital Zürich, Zürich/CH; ³ Ectica Technologies AG, Zürich/CH
P1.3.16 Contractile work contributes to maturation of energy metabolism in hiPSC-derived cardiomyocytes
B. Ulmer¹; A. Stoehr²; M. Schulze¹; S. Patel³; M. Gucek³; I. Mannhardt¹; S. Funcke¹; E. Murphy³; T. Eschenhagen¹; A. Hansen¹
¹ UKE, Hamburg/D; ² Karolinska Institutet, Huddinge/S; ³ National Heart Lung and Blood Institute, Bethesda/USA
P1.3.17 Development of microvascular structures inside porous fibrin coated polydioxanon and PLLA/PLGA scaffolds
S. Heene¹; S. Thoms¹; R. Jonczyk¹; T. Scheper¹; C. Blume¹
¹ Leibniz Universität Hannover, Hannover/D
   
Topic
1.4 Predictivity and validation

P1.4.01

Patient-derived 3D tumor cultures for clinical diagnostics and pre-clinical drug development.
S. Basten¹; B. Herpers¹; K. Yan¹; T. Giesemann²; J. Schueler²; W. Vader³; L. Price⁴;
¹ OcellO B.V., Leiden/NL; ² Charles River, Freiburg/D; ³ Vitroscan B.V., Leiden/NL; ⁴ OcellO B.V., Leiden/D

P1.4.02

Detailed Cell-Material Interactions in 3D Cell Culture Systems
R. Harjumäki¹; R. Nugroho²; J. Valle-Delgado²; Y. Lou¹; M. Yliperttula¹; M. Österberg²; ¹ University of Helsinki, Helsinki/FIN; ² Aalto University, Espoo/FIN

P1.4.03

Towards controlling the mobility of flowing cells in a hanging-drop network for microphysiological systems
N. Rousset¹; M. de Geus¹; A. Kaestli¹; K. Renggli¹; A. Hierlemann¹;
¹ ETH Zürich, D-BSSE Basel, Basel/CH

   
Topic
2.1 Translation of models to solutions

P2.1.01

Three-dimensional in vitro co-culture model for nanoparticle-mediated transfection
V. Sokolova¹; N. Bialas¹; L. Rojas¹; M. Epple¹;
¹ Inorganic Chemistry, University of Duisburg-Essen, Essen/D

P2.1.02

Microphysiological system based on human liver microtissues for intrinsic clearance prediction
F. Hürlimann¹; S. Mannino²; C. Lohasz³; K. Renggli³; A. Hierlemann³; L. Suter-Dick²; O. Frey¹; ¹ InSphero AG, Schlieren/CH; ² University of Applied Sciences and Arts Northwestern Switzerland, Muttenz/CH; ³ ETH Zürich, D-BSSE, Basel/CH

   
Topic
2.2 Clinical applications

P2.2.01

Silencing GALNT1 or GALNT2 suppresses malignant phenotypes of pancreatic cancer cells
T. Yeh¹; M. Huang²; ¹ National Taiwan University College of Medicine, 桃園市/RC; ² National Taiwan University College of Medicine, TAIPEI/RC

P2.2.02

Production of clinical grade temporary epidermal substitute obtained from hESC derived keratinocytes for the treatment of sickle cell leg ulcers: a challenge for regenerative medicine
S. Domingues¹; Y. Masson¹; A. Poulet¹; M. Saidani¹; J. Polentes¹; G. Lemaitre¹; M. Peschanski¹; C. Baldeschi¹; ¹ ISTEM/CECS, Corbeil-Essonnes/F

P2.2.03 Establishment of a Novel Functional in Vitro Assay to Investigate the Angiogenic Potential of Colonic Adenocarcinomas
S. Bring Truelsen¹; G. Hagel¹; N. Mousavi²; H. Harling²; K. Qvortrup²; O. Thastrup¹; J. Thastrup¹
¹ 2cureX A/S, Birkerød/DK; ² University of Copenhagen, Copenhagen/DK
   
TOPIC
3.1 Innovative, advanced analytics
P3.1.01 Imaging oxygen gradients in cell aggregates and in spheroids
R. Meier¹; R. Meier¹; ¹ PreSens Precision Sensing GmbH, Regensburg/D
P3.1.02 Application of video analysis for the evaluation of cardiac contractility in different in vitro model systems including freshly isolated adult rat cardiomyocytes and human iPSC-derived cardiomyocytes in 2D- and 3D-culture
P. Beauchamp¹; S. Adrian²; S. Longnus²; T. Suter²; C. Zuppinger³
¹ Bern University, Bern/CH; ² Bern University Hospital, Bern/CH;
³ University Hospital Bern, Bern/CH
   
Topic
3.2 Specific assay development

P3.2.01

Microfluidics: a powerful tool to recreate in vivo environment
C. Vergne¹; B. Rouffet²; S. Renard³; M. Verhulsel²;
¹ Fluigent, Villejuif/FP; ² Fluigent, Villejuif/F; ³ Fluigent GmbH, Jena/D

P3.2.02

An assay to characterize the impact of cigarette smoke exposure on mucociliary clearance in-vitro.
S. Frentzel¹; L. Ortega Torres¹; S. Majeed¹; P. Leroy¹; F. Zanetti¹; M. van der Toorn¹; M. Peitsch¹; J. Hoeng¹; ¹ Philip Morris Products S.A., Neuchatel/CH

P3.2.03

Minimalistic hydrogel matrices to direct early neural progenitors from pluripotent stem cells in 3D culture
A. Meinhardt¹; A. Ranga²; E. Tanaka³; M. Lutolf⁴; C. Werner⁵; ¹ Leibniz Institute of Polymer Research Dresden, Max Bergmann Center of Biomaterials Dresden, Dresden/D; ² KU Leuven, Leuven/B; ³ Research Institute of Molecular Pathology, Vienna/A; ⁴ Ecole Polytechnique Fédérale de Lausanne, Lausanne/CH; ⁵ Leibniz Institute of Polymer Research Dresden, Max Bergmann Center of Biomaterials Dresden, and Center for Regenerative Therapies Dresden, TU Dresden, Dresden/D

P3.2.04

Real-Time Assay for Apoptosis using Complementation of Annexin V Luciferase Subunits
T. Riss¹; K. Kupcho¹; J. Shultz¹; J. Hartnett¹; R. Hurst¹; W. Zhou²; R. Akiyoshi³; A. Niles¹; ¹ Promega Corporation, Madison/USA; ² Promega Biosciences, San Louis Obispo/USA; ³ Olympus Corporation, Tokyo/J

P3.2.05

Benefits of Real-Time Measurements of Cell Health in 2D or 3D Using a Plate Reader
T. Riss¹; ¹ Promega Corporation, Madison/USA

P3.2.06

Volume Regulation of HaCaT Spheroids in Response to Hypotonic Stimuli
E. von Molitor¹; ¹ Hochschule Mannheim, Mannheim/D

P3.2.07

Calcium signals in taste-bud like 3D cultures
T. Cesetti¹; E. von Molitor¹; R. Rudolf¹; M. Hafner¹; P. Scholz²; K. Riedel²
¹ Hochschule Mannheim, Mannheim/D; ² BRAIN AG, Zwingenberg/D

   
Topic
3.3 New devices for 3D cell culture

P3.3.01

Scaffold-Free Aggregate Cultivation of Mesenchymal Stem Cells in a Stirred Tank Bioreactor
C. Kasper¹; D. Egger²; I. Schwedhelm³; J. Hansmann³; ¹ Boku, Vienna/A; ² DBT - University of Natural Resources and Life Sciences (BOKU), Vienna/A; ³ Translational Center, University Hospital Wuerzburg, Würzburg/D

P3.3.02

Guiding 3D cell migration in deformed synthetic hydrogel micro-structures
M. Dietrich¹; H. Le Roy²; D. Brückner³; H. Engelke⁴; R. Zantl⁵; J. Rädler⁶; C. Broedersz³; ¹ Faculty of Physics and Center for NanoScience, Ludwig-Maximilians-University and ibidi GmbH, Munich/D; ² École Normale supérieure Paris-Saclay, Cachan/F; ³ Arnold-Sommerfeld Center for Theoretical Physics and Center for NanoScience, Ludwig-Maximilians-University, Munich/D; ⁴ Department of Chemistry and Center for NanoScience, Ludwig-Maximilians-University, Munich/D; ⁵ ibidi GmbH, Martinsried/D; ⁶ Faculty of Physics and Center for NanoScience, Ludwig-Maximilians-University, Munich/D

P3.3.03

Scaffold-Free Aggregate Cultivation of Mesenchymal Stem Cells in a Stirred Tank Bioreactor
C. Kasper¹; ¹ University of Natural Resources and Life Sciences, Vienna, Vienna/A

P3.3.04

Development, Characterization and Application of a Parallelizable Perfusion Bioreactor for 3D Cell Culture
D. Egger¹; M. Fischer¹; A. Clementi¹; J. Hansmann²; C. Kasper³; ¹ University of Natural Resources and Life Sciences, Vienna, Vienna/A; ² University Hospital Wuerzburg, Würzburg/D; ³ University of Natural Resources and Life Sciences, Vienna, Vienna/D

P3.3.05

A modular perfusion microbioreactor system for oxygen level control and optimization for bone tissue engineering
J. Schmid¹; M. Schieker²; R. Huber¹; ¹ University of Applied Sciences Munich, Munich/D; ² Ludwig-Maximilians University Munich (LMU), Munich/D

P3.3.06

Gelatin-based hydrogels for 3D cell culture: stability at physiological temperatures by UV-crosslinking or nanoparticles
K. Kruppa¹; A. Lavrentieva²; T. Scheper¹; I. Pepelanova³; ¹ Institute of Technical Chemistry, Leibniz University Hanover, Hannover/D; ² Institute of Technical Chemistry/Leibniz University Hanover, Hannover/D; ³ Institute of Technical Chemistry, Hannover/D

P3.3.07

A tubing-free, microfluidic tilting platform for the realization of in vivo-like drug exposure scenarios for three-dimensional microtissues
C. Lohasz¹; O. Frey²; K. Renggli¹; A. Hierlemann¹; ¹ ETH Zürich, Basel/CH; ² Insphero AG, Schlieren/CH

P3.3.08

Organ-on-a-Disc – Enabling technology for the parallelization and automation of microphysiological systems
S. Schneider¹; O. Schneider¹; F. Erdemann¹; C. Probst¹; P. Loskill¹; ¹ Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB, Stuttgart/D

P3.3.09

Porous, ultralight 3D tubular scaffolds from short electrospun nanofibers
M. Merk¹; C. Adlhart¹; ¹ ZHAW Zürcher Hochschule für Angewandte Wissenschaften, Wädenswil/CH

P3.3.10

Enhanced cardiomyocyte maturation in a microfluidic system as a potential platform for pharmacological screening
T. Kolanowski¹; M. Busek²; S. Grünzner³; F. Sonntag²; K. Guan¹; ¹ TU Dresden, Faculty of Medicine Carl Gustav Carus, Institute of Pharmacology and Toxicology, Dresden/D; ² Fraunhofer Institute of Material and Beam Technology IWS, Dresden/D; ³ Fraunhofer Institute of Material and Beam Technology IWS; TU Dresden, Faculty of Manufacturing Technology, Dresden/D

P3.3.11

Autonomous Plug&Play Multi-Organ-Chips with Integrated Pumping and Sensing
F. Sonntag¹; C. Probst²; S. Grünzner³; M. Busek⁴; P. Loskill⁵; ¹ Fraunhofer-Institut für Werkstoff- und Strahltechnik IWS, Dresden/D; ² Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB, Stuttgart/D; ³ Fraunhofer Institute for Material and Beam Technology IWS / Dresden University of Technology, Dresden/D; ⁴ Fraunhofer Institute for Material and Beam Technology IWS, Dresden/D; ⁵ Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB / Eberhard Karls University Tübingen, Stuttgart/D

P3.3.12

vasQchip: A blood vessel scaffold for the reconstruction and 3D bioprinting of 3D-tissues in vitro
U. Schepers¹; ¹ Karlsruhe Institute of Technology (KIT), Eggenstein-Leopoldshafen/D

P3.3.13

A non-invasive microscopy platform for the online monitoring of human induced pluripotent stem cell aggregation in suspension cultures in small-scale stirred tank bioreactors
I. Schwedhelm¹; D. Egger²; P. Wiedemann³; T. Schwarz⁴; H. Walles¹; J. Hansmann⁴
¹ University Hospital Würzburg, Würzburg/D; ² University of Natural Resources and Life Sciences, Vienna/A; ³ Mannheim University of Applied Sciences, Mannheim/D; ⁴ Fraunhofer Institute for Silicate Research ISC, Würzburg/D

P3.3.14

Comparison of 2D and 3D cultures of primary hepatocytes on hepatocellular functions and hepatotoxicity
H. Dinter¹; A. Ullrich²; D. Runge²
¹ Hochschule Biberach, Biberach/D; ² Primacyt Cell Culture Technology GmbH, Schwerin/D

P3.3.15 Funnel-Guided Positioning of Multi-cellular Microtissues to Build Macrotissues
K. Manning¹; A. Thomson²; J. Morgan²
¹ Brown University, Providence, RI/USA; ² Brown University, Providence/USA
P3.3.16 A novel 3D microwell array for analysis of adhesion independent micro-tumours
A. Thomsen¹; C. Aldrian²; Y. Thomann³; A. Grosu²; P. Bronsert⁴; M. Leu⁵; P. Lund⁶
¹ University Medical Center Freiburg, Freiburg/D; ² Medical Center – University of Freiburg, Freiburg/D; ³ Freiburg Material Research Center and Institute for Macromolecular Chemistry, Freiburg/D; ⁴ Institute for Surgical Pathology, Medical Center – University of Freiburg, Freiburg/D; ⁵ abc biopply ag, Solothurn/CH; ⁶ Department of Radiation Oncology, Ortenau-Klinikum, Offenburg/D
P3.3.17 Integration of 3d printed hollow hydrogel fiber with microfluidic system to develop a perfusable nephron model.
A. Akkineni¹; D. Förster²; J. Sardnick²; F. Schmieder³; F. Sonntag³; M. Gelinsky¹; A. Lode¹
¹ Centre for Translational Bone, Joint and Soft Tissue Research, TU Dresden, Dresden/D; ² University Hospital Carl Gustav Carus, TU Dresden, Dresden/D; ³ Fraunhofer Institute for Material and Beam Technology IWS, Dresden/D
   
Topic
3.5 High-throughput and automatisation

P3.5.01

Impedance analysis of viability of Schistosoma mansoni larvae for drug screening application
M. Modena¹; K. Chawla¹; F. Lombardo²; S. Burgel¹; G. Panic²; J. Keiser²; A. Hierlemann¹; ¹ ETH Zürich; ² University of Basel

P3.5.02

Magnetic 3D Bioprinting for High-Throughput and Automated Hepatotoxicity Testing
G. Souza¹; B. Larson²; ¹ The University of Texas Health Science Center, Houston/USA; ² Biotek Instruments, Inc., Winooski/USA

P3.5.03

Cytotoxicity Evaluation of Nanoparticles using Automatic 3D Cell Culture System
M. Heo¹
¹ Korea Research Institute of Standards and Science, Yuseong-gu, Daejeon/ROK

P3.5.04

Automated large-scale production and deposition of spheroids
K. Tröndle¹; ¹ University of Freiburg, Technical Faculty, Freiburg/D

   
Topic
3.6 3D printing

P3.6.01

Characterization of GelMa and alginate hydrogels for bioprinting:
printability, polymerization and biocompatibility

L. Raddatz¹; C. Schmitz¹; P. Gellermann¹; M. Kirsch¹; D. Geier²; S. Beutel¹; T. Becker²; T. Scheper³; I. Pepelanova¹; A. Lavrentieva¹; ¹ Institute of Technical Chemistry, Leibniz University Hanover, Hannover/D; ² Institute of Brewing and Beverage Technology, Forschungszentrum Weihenstephan, Technical University Munich, Munich/D; ³ Institute of Technical Chemistry/Leibniz University Hanover, Hannover/D

P3.6.03

Engineering bio-mimetic vasculature with photolithographic
fabrication techniques

A. Thomas¹; K. Schimek¹; G. Giese²; A. Kreuder¹; T. Grix¹; L. Kloke³;
¹ Technische Universität Berlin, Berlin/D; ² Freie Universität Berlin, Berlin/D; ³ Cellbricks GmbH, Berlin/D

P3.6.04

Characterisation of bioprinted mandibular osteoblasts for engineering an
in vitro jaw bone model

A. Amler¹; A. Thomas¹; T. Grix¹; R. Lauster¹; L. Kloke²
¹ TU Berlin, Berlin/D; ² Cellbricks GmbH, Berlin/D

P3.6.05

3D Bioprinting of hydrogels for viral Infection and transduction with
viral gene vectors

T. Hiller¹; ¹ TU Berlin, Berlin/D

P3.6.06

3D-printed drug delivery systems for cell therapy:
A new approach for the treatment of Diabetes Mellitus

A. Pössl¹; P. Schlupp¹; T. Schmidts¹; F. Runkel¹
¹ Technische Hochschule Mittelhessen, Gießen/D

P3.6.07

Imaging of O2 concentration and spatial distribution in
3D bioprinted hydrogel scaffolds using O2 sensing nanoparticles

A. Akkineni¹; A. Lode¹; E. Trampe²; K. Koren²; F. Krujatz¹; M. Kühl²; M. Gelinsky¹
¹ Technische Universität Dresden, Dresden/D; ² University of Copenhagen, Copenhagen/DK

P3.6.08 Modelling of a microfluidic device to study tumor cell extravasation
C. Kühlbach¹; R. Glunz¹; M. Mueller¹; F. Baganz²; V. Hass¹
¹ HFU Hochschule Furtwangen University, Villingen-Schwenningen/D; ² UCL University College London, London/UK

 

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