PRAXISforum Enzymes for Industrial Applications 2018



Yasuhisa Asano, Toyama Prefectural University

Yasuhisa Asano
Head of Enzyme Chemistry Laboratory
Toyama Prefectural University, Biotechnology Research Center/Japan


"Active enzymes: Actively expressed enzymes in heterologous hosts are always necessary.
Enzyme activity: Activity measurement is important in enzyme discovery.
Enzyme molecule: Enzymes are improved by looking at protein structure in molecular level."

Kai Baldenius, BASF

Kai Baldenius
Head of Biocatalysis Research,


"We haven’t fully appreciated the potency of enzyme catalysis. Let’s move out of the chiral niche and target chemical production more broadly!"

Sven Benson, candidum

Sven Benson
Co-founder & CEO,

"One of the major bottlenecks to making biocatalysts economically viable is to find the right solutions for specific catalytic challenges within the vast diversity of enzyme blueprints. candidum sets out to drive innovation by making this process simple, budgetable, at competitive costs and with minimal risks."

Fredi Brühlmann, Firmenich

Fredi Brühlmann
Group leader Biotechnology Department


"Enzymes offer highly versatile chemistries under benign conditions enabling diverse applications. While an increasing range of engineering options helps addressing performance and cost issues among others, it is important that the regulatory environment and the public remain open to science and technology."

Andrea Dreusch, MicroMol

Andrea Dreusch


"Phages are much more than a redoubtable contamination. If you deal with a good risk management they might be friends. There are much more possibilities to talk about bacteriophages than only to execrate them."

Christian Jäckel, Chr. Hansen

Christian Jäckel
Senior Research Scientist in Enzyme Innovation,
Chr. Hansen/Denmark


"Quality over quantity: Smart library design strategies and screens close to application are key to successful discovery of superior industrial enzymes."

Michael Klingeberg, Südzucker

Michael Klingeberg
CRDS – Senior Manager Microbiology, Südzucker/Germany


"Challenges: Continuous improvement process in large scale application, is it possible to measure yield increases of 1 %?"

Maria Fátima Lucas, Zymvol Biomodeling

Maria Fátima Lucas
Co-founder & CEO,
Zymvol Biomodeling/Spain

"In silico industrial enzyme design is changing the way we work. You can now look into your enzyme and accurately predict improvements."

Riccardo Motterle, F.I.S. - Fabbrica Italiana Sintetici S.p.A.

Riccardo Motterle
Head Biotechnology Development,
F.I.S. - Fabbrica Italiana Sintetici S.p.A./Italy

"Enzymes availability and possibility to improve them using Evolution makes a nonsense avoiding to evaluate biocatalysis in new synthesis design."

Jörg Ohl, Corden BioChem

Jörg Ohl
Senior Business Development Manager,
Corden BioChem/Germany


"Contract Manufacturing becomes more and more important in biotechnology. For strategical as well as tactical outsourcing, a reliable and experienced partner delivering on-time and in the right quality is a must."

Alexander Pelzer, BRAIN

Alexander Pelzer
Platform Coordinator Tailor-made Biocatalysts,

"Enzyme product development is a multidisciplinary task that requires the combination of excellence in diverse fields like enzyme discovery and identification, microbial enzyme production and formulation of the enzyme in an application compatible formula with long storage stability."

Audrey Robic, Protéus

Audrey Robic
Scientific Manager,

"To increase the chances of success in finding the best biocatalyst and process conditions for your applications, it is important to access panels of biocatalysts ready for screening and a streamlined methodology to assess rate-limiting process parameters."

Martin Schürmann, InnoSyn

Martin Schürmann
Principal Scientist Biocatalysis,
InnoSyn/The Netherlands


"To compete with conventional chemistry we have to improve and speed up enzyme and reaction engineering to bring more biocatalysis processes from academic proof-of-principle to industrial application."

Wojtek Steffen, Roche Diagnostics

Wojtek Steffen
Project Leader Enzyme and Protein Technologies, Roche Diagnostics GmbH/Germany


"Conventional chemical strategies for protein conjugation are often lacking in site-specificity, linkage stability and reaction conditions. This effected the development of biocatalysts that confer regioselectivity for site-specific modification. Microbial Transglutaminases have long been known as promiscuously 'protein-glueing' enzymes in food technology, but are now emerging as highly specific, versatile and inexpensive tools for a broad range of industrial applications."

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