From new drug candidates and predictive cell culture models to development and manufacturing of innovative (bio-)pharmaceuticals to nanobiomedical applications.
EFCE-Event-Nr. 751 Support and Media Partner Support Partner
The 3D Cell Culture 2021 conference will focus on advanced and predictive 3D cell culture models for the understanding of diseases and substance testing....
Does today's process simulation meet the requirements posed by increasing digitalisation up to the "digital twin"? This question is addressed by the experts of the ProcessNet working committee Process Simulation, Process Synthesis and Knowledge Processing in their current position paper "Process Simulation - Fit for the Future?
These recommendations provide suitable experimental methods for the process engineering characterisation of single-use bioreactors and mixers.
1. Talk: 26. November 2020, 15-16h
2. Talk: 3. Dezember 2020, 15-16h
The conference will highlight latest developments in the field from research and application: Advanced cell culture models for understanding of...
2. revised edition
The Escherichia coli model process described in the recommendation also makes it possible to characterise the biological performance of a system. The standardised process aims to determine the performance of bioreactors, in particular single-use bioreactors, and to evaluate their suitability for microbial applications. Since microbial processes place high demands on the bioreactor system with regard to oxygen transfer, this is of particular importance; another important parameter is heat removal.
The associated Excel tool offers the possibility of a standardised evaluation, so that a comparison across bioreactor systems is possible. Calculations, e.g. of the volumetric mass transfer coefficient, will be performed automatically after input of the raw data.
Recommendation and Excel tool were developed by the "Single-Use Microbial" working group of DECHEMA's expert group "Single-Use Technology in Biopharmaceutical Manufacturing".