POSTPONED
Due to the situation caused by the new corona virus we had to postpone the 3D Cell Culture 2020 conference previously scheduled 12-14 May this year.
Here we would like to inform you about the NEW DATE:
3D Cell Culture 2021 (5-7 May 2021, Konzerthaus Freiburg, Germany)
Please save the date, all further information will follow.
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From bench to applications
Get updated about 3D cell culture as predictive model systems and the translation from models to applications!
Hansjörg Hauser, Helmholtz Centre for Infection Research, Braunschweig/D
Jens M. Kelm, PreComb Therapeutics AG, Wädenswil/CH
Uwe Marx, TissUse GmbH, Berlin/D
Tobias May, InSCREENeX GmbH, Braunschweig/D
Ralf Pörtner, Hamburg University of Technology/D
Ina Prade, Forschungsinstitut für Leder und Kunststoffbahnen (FILK) gGmbH, Freiberg/D
Markus Rimann, Zurich University of Applied Science, Wädenswil/CH
Heinz Ruffner, Novartis Institutes for BioMedical Research, Basel/CH
Karin Tiemann, DECHEMA e. V., Frankfurt am Main/D
Tuesday, 12 May 2020 (incl. Poster Speed Lectures, Part 1)
Wednesday, 13 May 2020 (incl. Poster Speed Lectures, Part 2)
| 11:00 |
Registration |
|---|---|
| 12:00 |
Business Lunch |
| 12:55 |
Welcome Address |
Biofabrication of 3D Models |
|
| Chair: |
M. Rimann, Zurich University of Applied Sciences, ICBT, Wädenswil/CH |
| 13:00 |
Keynote Lecture 1 Biofabrication of 3D tissues for disease modeling and drug discovery |
| 13:45 | Bio-printable 3D in vitro Tumor-Tissue-Modell for high throughput testing of tumortherapeutica M. Mueller¹; S. Hensler¹; C. Kühlbach¹; R. Glunz¹ ¹ Furtwangen University, Villingen-Schwenningen/D |
| 14:05 | Drop-on-demand bioprinting solutions for the fabrication of 3D cell culture systems aiming for in vitro screening applications K. Tröndle¹; A. Itani¹; F. Koch¹; R. Zengerle²; S. Zimmermann¹; P. Koltay¹ ¹ University of Freiburg/D; ² Hahn Schickard, Freiburg/D |
| 14:25 |
3D-printed mini-bone-organs with living osteocyte networks |
| 14:45 |
A microengineered platform for single cell tracking in 3D stem cell-based morphogenesis models |
| 15:05 | Coffee Break / Posters / Exhibition |
Synthetic Biology for Future Treatment Strategie |
|
| Chair: | R. Pörtner, TU Hamburg/D |
| 15:45 |
Keynote Lecture 2 Synthetic biology-inspired cell-based treatment strategies of the future |
| 16:30 |
Introduction Poster Speed Lectures and Poster Awards |
Poster Speed Lectures - Part 1 |
|
| Chair: |
R. Pörtner, TU Hamburg, Hamburg/D |
| 16:35 |
P3.3.06 Smarter surfaces to create cellular niches without artefactsT. Mentzel¹; A. Thomas¹; P. Lak¹; V. Schwartz¹; J. Sloan²; B. Birk²; P. Hahn²; P. Stengel²; N. Kaiser²; C. Oberfrank² ¹ Chemovator GmbH, Mannheim/D; ² BASF SE, Ludwigshafen/D |
| 16:39 |
P1.4.02 A versatile microfluidic tilting platform for investigating crosstalk between 3D microtissues and free-flowing cells |
| 16:43 |
P3.4.01 Optical clearing of 3D-cell cultures for substance screening |
| 16:47 |
P1.1.07 HA-based delivery system enhances drug transport to tumor spheroidsJ. Starigazdova¹; D. Zelencova²; K. Nesporova¹; D. Smejkalova¹; G. Huerta-Angeles¹; V. Velebny¹ ¹ Contipro, Dolní Dobrouc/CZ; ² The University of Veterinary Medicine and Pharmacy in Kosice/CZ |
| 16:51 |
P3.5.03 Impact of A Disintegrin And Metalloprotease 17 (ADAM17) inhibition combined with paclitaxel treatment in ovarian cancer spheroids |
| 16:55 |
P1.3.08 Potential and limitations of hybrid supramolecular-polysaccharide hybrid hydrogels for macrophage 3D cell culture modelsD. Hebel¹; M. Müller¹ ¹ University Siegen/D |
| 16:59 |
P1.2.03 Applying a microphysiological 3D human liver – islet microtissue platform to study metabolic diseases |
| 17:03 |
P1.1.10 Matrix-free culture of intestinal organoids in thermoformed microwells |
| 17:07 |
P1.3.02 Manufacturing of functional beta cell-mesenchymal stem cell-spheroids for transplantation or drug testing |
| 17:11 |
P3.3.02 Modular plug&play construction kit for the development of micro-physiological systems |
| 17:15 |
P3.6.02 Hydrogels formed from methylsulfone-bearing polymers provide convenient crosslinking kinetics for 3D cell culture and bioprintingS. Pearson¹; A. de Miguel Jiménez¹; R. Valbuena Mendoza¹; J. Paez¹; A. del Campo¹ ¹ INM-Leibniz Institute for New Materials, Saarbrücken/D |
| 17:19 |
P1.5.01 Autologous endothelial colony forming cells as promising cell source for endothelialization of TEVGsX. Kraus¹; M. Pflaum²; S. Thoms¹; R. Jonczyk¹; C. Blume¹; T. Scheper¹ ¹ Leibniz University Hanover/D; ² Medical University Hannover/D |
| 17:23 | End of Lecture Programme of Day 1 |
| 17:30 | Poster Session 1 / Poster Party (17:30-20:00) |
| 18:00 |
Section Member Assembly (18:00 – 19:00) DECHEMA Working Groups Cell Culture Technology and Medical Biotechnology |
Models for Host-Microbe Interactions |
|
| Chair: | H. Hauser, Helmholtz-Zentrum für Infektionsforschung (HZI), Braunschweig/D |
| 09:00 |
Keynote Lecture 3 Organoids: transformative tools to dissect innate immune responses to host-microbe interactionsN.C. Zachos¹ ¹ Johns Hopkins University School of Medicine, Baltimore, MD/USA |
| 09:45 | Microstructured 3D in vitro model of the small intestine epithelium for studying host-bacteria interactions M. García-Díaz¹; M. Cendra¹; R. Alonso-Román¹; E. Torrents¹; E. Martínez¹ ¹ Institute for Bioengineering of Catalonia (IBEC), Barcelona/E |
| 10:05 |
Microfluidic gut-liver axis - a platform for studies on host-microbiota interaction |
| 10:25 | Coffee Break / Posters / Exhibition |
From Blood-Brain Barrier to Heart Design |
|
| Chair: | I. Prade, FILK gGmbH, Freiberg/D |
| 11:00 | 3D blood brain barrier organoids as in vitro model for the biomedical application of ultrasmall gold nanoparticles V. Sokolova¹; S. van der Meer¹; T. Ruks¹; M. Epple¹ ¹ University of Duisburg-Essen, Essen/D |
| 11:20 | Force measurement apparatus for 3D bioprinted muscle tissues in multi well plate for drug development M. Rimann¹; M. Nosswitz¹ ¹ Zurich University of Applied Sciences, Wädenswil/CH |
| 11:40 |
Tissue brick macro-scale organ engineering for trabecular heart design |
| 12:00 |
Short Break |
Poster Speed Lectures - Part 2 |
|
| Chair: | I. Prade, FILK gGmbH, Freiberg/D |
| 12:05 |
P1.3.06 Investigation of tumor cell extravasation in a novel microfluidic device |
| 12:09 |
P1.3.09 Cancer associated fibroblasts shape the phenotype of macrophages in organotypic 3D colon cancer models |
| 12:13 |
P1.5.02 Isolation of patient-derived peritoneal colorectal cancer metastases and 3D cultivation in different matricesM. Sachet¹; H. Birnleitner¹; J. Stift¹; T. Bachleitner-Hofmann¹; M. Bergmann¹; H. Dolznig¹; R. Oehler¹ ¹ Medical University of Vienna/A |
| 12:17 |
P1.1.02 Targeting the fibrotic tumor microenvironment: Novel 3D co-culture organoids for pancreatic adenocarcinoma (PDAC) drug discoveryJ. Hänsel¹; B. Xie²; A. Ni Putu³; P. Proksch³; R. Mrsny²; N. Teusch¹; H. Yu³ ¹ Universität Osnabrück/D; ² University of Bath/UK; ³ Heinrich-Heine-University Düsseldorf/D |
| 12:21 |
P1.2.02 Development of vascularized melanoma skin equivalents for studying metastasis and anti-melanoma therapies |
| 12:25 |
P1.3.03 Evaluation of different long-term culture approaches for primary human hepatocytes and an optimized transfection method |
| 12:29 |
P1.1.03 Mesenchymal stem cell growth and differentiation in 3D systems under the influence of human platelet lysate |
| 12:33 |
P3.6.01 Mechanical properties of 3D printed scaffolds for heart valve tissue engineering |
| 12:37 |
P1.1.08 Novel biomimetic membranes for nanoparticle transport studies at biological barriers |
| 12:41 |
Lunch |
| 13:30 |
Poster Session 2 and Poster Prize Voting |
Liver Models and Toxicity Testing |
|
| Chair: | J. Kelm, PreComb Therapeutics AG, Wädenswil/CH |
| 14:30 |
Keynote Lecture 4 Do results from in vitro toxicity models translate to the human situation in vivo? |
| 15:15 |
Keynote Lecture 5 Prediction of human drug-induced liver injury (DILI) in relation to oral doses and blood concentrations |
| 16:00 |
HepaChipMWP – a microfluidic, perfusable and scalable in vitro model of the liver in multiwellplate format |
| 16:20 |
Coffee Break / Posters / Exhibition |
Advanced Assays and Devices |
|
| Chair: | T. May, InSCREENeX GmbH, Braunschweig/D |
| 16:50 |
Live cell imaging of perfused human taste cell-derived spheroids |
| 17:10 |
CellPulse: single pulse laser poration of cells |
| 17:30 |
Advanced in vitro management of three-dimensional cell cultures and explanted tissue |
| 17:50 | Avoiding common pitfalls of 3D culture model assay development with appropriate validation and controls T. Riss¹ ¹ Promega Corporation, Madison, WI/USA |
| 18:10 |
End of Lecture Programme of Day 2 |
| 19:30 |
Scientific Award Ceremony / Conference Dinner Schlossberg Restaurant Dattler |
3D Models for Molecular Mechanisms |
|
| Chair: | H. Ruffner, Novartis Institutes for BioMedical Research, Basel/CH |
| 09:00 |
Keynote Lecture 6 Organotypic 3D models to characterize the molecular requirements of immune cell infiltration and activation |
| 09:45 |
Molecular control of ErbB2/Her2-driven 3D breast tumor growth: mechanistic and therapeutic implications |
| 10:05 |
Development of a 4D-in vitro-test system for specificity and po-tency of 3rd generation chimeric antigen receptor-T-cells (CAR-T-cells) based on microcavity array-bioreactors |
| 10:25 | A patient-based 3D breast cancer cell model to tackle ER signalling A. Cartaxo¹; M. Estrada¹; G. Domenici¹; R. Roque²; F. Silva²; E. Gualda³; P. Loza-Alvarez³; S. André²; C. Brito¹ ¹ iBET, Instituto de Biologia Experimental e Tecnológica & Instituto de Tecnologia Química e Biológica António Xavier, Oeiras/P; ² IPOLFG, Lisboa/P; ³ ICFO, Castelldefels, Barcelona/E |
| 10:45 | Coffee Break / Posters / Exhibition |
From 3D Models to the Clinic |
|
| Chair: |
U. Marx, TissUse GmbH, Berlin/D |
| 11:15 |
Keynote Lecture 7 Advancing regulatory science through innovation; in vitro microphysiological systems |
| 12:00 | Mimicking human cancer heterogeneity and diversity by building the largest biobank of matched in vitro (organoid) and in vivo (PDX) X. Xu¹; P. Wang²; J. Zhou²; H. Li³ ¹ Crown Bioscience, Inc., Beijing/PRC; ² Crown Bioscience, Inc., Taicang/PRC; ³ Crown Bioscience, Inc., San Diego, CA/USA |
| 12:20 | OncoChip – a novel microfluidic platform for compound efficacy testing on human 3D microtumors M. Pawlak¹; S. Yüz²; B. Gierke¹; J. Hofmann³; U. Härle²; S. Werner²; B. Hagmeyer²; Z. von Guttenberg³; M. Stelzle²; C. Schmees² ¹ NMI TT Pharmaservices, Reutlingen/D; ² NMI Natural and Medical Sciences Institute at the University of Tübingen, Reutlingen/D; ³ ibidi GmbH, Gräfelfing/D |
| 12:40 | A new approach to synergize hyperthermia and radiotherapy in cancer treatments using an in vitro 3D micro-tumour system A. Thomsen¹; C. Aldrian¹; P. Lund²; A. Grosu¹; M. Leu³; P. Vaupel¹ ¹ University of Freiburg, Medical Center/D; ² Ortenau-Klinikum, Offenburg/D; ³ abc biopply ag, Solothurn/CH |
| 13:00 |
Closing Remarks |
| 13:10 |
Lunch |
| 14:00 |
End of the Conference |
Please select "Posters" for the "Form of Presentations". Poster authors can find the new poster numbers here.
The exhibition, integrated in the conference, offers a unique opportunity to promote your technologies products, and services in the 3D cell culture field.
Book your Exhibition Package through the button below or contact the Conference Office for further information.
Standard Exhibition Package (1800 € + VAT for taxable supplies)
• Exhibition space (6 sqm) for the duration of the conference
• Basic equipment: 1 table, 1 chair, power supply
• 1 conference participation included
• Company logo on the conference website, in the printed programme, book abstracts and on the conference slides
Option to book 1 additional conference participation for the reduced fee of 435 €
Advertisement Back Cover (1000 € + VAT)
(one sponsor only)
Advert in the conference programme / book of abstracts (colour, size DIN A5)
back cover page (U4)
Advertisement Inside Page (500 € + VAT)
Advert in the conference programme / book of abstracts (black/white, size DIN A5)
Display of printed matter (200 € + VAT)
Display of your printed advertising material or publication (price per title) on a table for the duration of the conference
Additional Options and Advertisement
For sponsorship of Poster Party and Scientific Award Ceremony please contact us.
The conference will highlight latest developments in the field from research and application:
Advanced cell culture models for understanding of diseases and substance testing, including complex and multi-cell type models, organ-on-a-chip and microphysiological systems as well as models for personalized medicine and in vitro application of patient-derived tissues.
Translation, clinical and industrial applications: How can models be turned into solutions? Success stories and current developments both for clinical and industrial applications will be presented. What regulatory aspects need to be considered, e.g. in the context of preclinical drug evaluation, and where are the current gaps between 3D models and clinic?
Innovative enabling technologies: The successful development and application of 3D cell culture relies on innovative, advanced analytics and specific assay development as well as on imaging technologies. Bioinformatics, systems biology and modelling enable the targeted development of 3D cell culture. New devices or technologies like 3D printing and bioprinting open up new possibilities. High-throughput and automatization allow for rapid compound screening.
Since our first symposium in 2009, the 3D Cell Culture conference series has developed into a ‘place to be’ for experts in this field. 3DCC2020 will highlight newest developments and the translation of models to applications. Success stories and trends like 3D models for personalized medicine will be presented as well as innovative technologies. Relevant disease models, applications of 3D models in clinic and industry, predictive cell models for compound characterization, safety and toxicity testing, and a range of enabling technologies will be covered.
In addition to scientific presentations, the exhibition will showcase practical applications, products and solutions and further stimulate discussion between researchers, solution providers and users.
The 3D Cell Culture conference is an initiative of the DECHEMA working groups “Cell Culture Technology” and “Medical Biotechnology”
in cooperation with
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Image source: Volha - stock.adobe.com (background); toodtuphoto - stock.adobe.com
DECHEMA-Fokus-Themen:
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