P01 Chip-based antibody-array for single-molecule sensitive detection of Tuberculosis
antigen
R. Schmidt, German Cancer Research Center, Heidelberg; J. Jacak, Johannes Kepler
University Linz/A; C. Schirwitz, German Cancer Research Center, Heidelberg; V. Stadler,
PEPperPRINT GmbH, Heidelberg; G. Michel, Foundation for Innovative New Diagnostics
(FIND), Geneva/CH; N. Marmé, University of Heidelberg; G.J. Schütz, Johannes Kepler
University Linz/A; J.D. Hoheisel, J.P. Knemeyer, German Cancer Research Center,
Heidelberg
P02 Solving the mystery of the amino linker: understanding immobilization of molecules on
microarray surfaces
J. Sobek, R. Schlapbach, Functional Genomics Center Zurich/CH; W. Weigel, Humboldt
University of Berlin
P03 Pseudomonas putida KT2440 genome update by cDNA sequencing and microarray
transcriptomics
S. Frank, J. Klockgether, Hannover Medical School; P. Hagendorf, R. Geffers, Helmholtz
Centre for Infection Research, Braunschweig; U. Schöck, T. Pohl, GATC Biotech AG,
Konstanz; C. Davenport, B. Tümmler, Hannover Medical School
P04 Extreme properties of genomes and their information capacity
A.A. Koval, V.M. Lougovoy, Siberian Federal University, Krasnoyarsk/RUS; M.G. Sadovsky,
Institute of Computational Modelling of SB RAS, Krasnoyarsk/RUS
P05 Highly parallel characterization of gene function
M. Boettcher, J. Fredebohm, J. Wolf, J.D. Hoheisel, German Cancer Research Center,
Heidelberg
P06 Combinatorial symmetry in genomes
E. Temlyakova, V. Lougovoy, Siberian Federal University, Krasnoyarsk/RUS;
M. Sadovsky, Institute of Computational Modelling SB RAS, Krasnoyarsk/RUS
P07 Deep sequencing of mitochondrial genomes and transcriptomes
J. Altmüller, C. Becker, University of Cologne; G. Zsurka, University of Bonn;
R. Bundschuh, Ohio State University, Columbus, OH/USA; W. Kunz, University of Bonn;
J. Gott, Case Western Reserve University, Cleveland, OH/USA; P. Nürnberg, University
of Cologne
P08 Passage: a fast and efficient sequence clustering method for RNA-seq data without a
reference genome
F. Battke, Center for Bioinformatics, Tuebingen; S. Körner, S. Hüttner, Hölle & Hüttner AG,
Tuebingen; K. Sohn, Fraunhofer IGB, Stuttgart; K. Nieselt, Center for Bioinformatics,
Tuebingen
P09 Sol-gel system broad utility in binding assays future: from target discovery to drug
development
M. Jo, S. Lee, H. Andrade, B.-D. Han, PCL Inc., Suwon/ROK; W. Weigel, J. Hempel,
Scienion AG, Berlin
P10 Identification of new causative genes in patients with adenomatous polyposis by CNV
analysis
S. Horpaopan, S. Vogt, I. Spier, M.M. Nöthen, P. Hoffmann, S. Aretz, University of Bonn
P11 CMOS polysaccharide microarrays for fast vaccination control
J. Baader, H. Klapproth, S. Bednar, T. Brandstetter, J. Rühe, University of Freiburg;
H. Eibel, H.-H. Peter, University Hospital Freiburg; M. Lehmann, I. Freund, Micronas
GmbH, Freiburg
P12 Microarray-based amplification and detection of microRNAs (miRNAs) by NASBA
(nucleic acid sequence based amplification)
U. Riehle, University Hospital Freiburg; A. Mader, T. Brandstetter, J. Rühe, University of
Freiburg; A. zur Hausen, E. Stickeler, University of Freiburg
P13 Towards quantitative microarray-based NASBA: real-time kinetic recording by
competitive displacement
A. Hoppmann, A. Mader, T. Brandstetter, J. Rühe, University of Freiburg
P14 Quantitative protein biomarker analysis in formalin fixed tissues - searching for
industrial collaboration
K. Malinowsky, C. Wolff, K.-F. Becker, Technische Universität München
P15 Dual-colour protein analysis on complex antibody microarrays for the profiling of
cancer proteomes
C. Schröder, A. Jacob, M.S.S. Alhamdani, A. Nieters, S. Rüffer, A. Bauer, K. Fellenberg,
J.D. Hoheisel, German Cancer Research Center, Heidelberg
P16 Inferring gene-regulatory networks via correlation
M. Maucher, Ulm University Hospital; B. Kracher, M. Kühl, University of Ulm; M. Buchholz,
T. Gress, Marburg University Hospital; H.A. Kestler, University of Ulm
P17 Protein quantification using reverse phase protein microarrays
R. Wild, H. Seitz, MPI for Molecular Genetics, Berlin
P18 Tumor master stem cells and their rapid genetic modification: the incentive to further
development of a new generation in chip-technology
N. Klehr, L.H. Bauer, Dr. Klehr Institut für Immunologie und Zellbiologie, Munich; S. Sowa,
J. Setter, Haemotec GmbH, Grünwald
P19 Parallelized functional characterization of pancreatic cancer candidate genes on
reverse transfection cell microarrays
S. Melchisedech, T. Honstein, R. Kreider, T.M. Gress, M. Buchholz, University of Marburg
P20 Differentiation of multiple histological subtypes of pancreatico-biliary tumors by
molecular analysis of clinical specimens
T.M. Gress, University of Marburg; H.A. Kestler, L. Lausser, University of Ulm; B. Sipos,
University Hospital Tuebingen; C. Michalski, Technical University Munich; N. Giese,
J. Werner, University of Heidelberg; A. Scarpa, University of Verona/I; M. Buchholz,
University of Marburg
P21 Expression profiling of marine microbial communities with 454 pyrosequencing
A. Klindworth, C. Klockow, E. Karamehmedovic, B. Öztürk, H. Teeling, J. Waldmann,
A. Mann, T. Hammer, F.O. Glöckner, MPI for Marine Microbiology, Bremen
P22 Analyzing splicing patterns by high-resolution RNA-Seq expression profiles
R. Deenen, T. Wachtmeister, Heinrich Heine University Düsseldorf; H. Schaal, M. Widera,
University Hospital Düsseldorf; K. Köhrer, Heinrich Heine University Düsseldorf
P23 Cross array platform miRNA profiling during cardiomyocyte-specific differentiation of
ESCs
L. Gan, RWTH Aachen University; S. Schwengberg, Axiogenesis AG, Cologne;
B. Denecke, RWTH Aachen University
P24 Unbiased quantitative pyrosequencing assay reveals concurrent epigenetic silencing
of Wnt signaling inhibitors in B-cell chronic lymphocytic leukemia
E.A. Moskalev, German Cancer Research Center, Heidelberg; I.A. Vorobjev,
A.A. Gladkikh, National Hematology Research Center, Moscow/RUS; M.G. Zavgorodnij,
Voronezh State University/RUS; S.P. Majorova, Voronezh State Technical University/RUS;
A. Stephan, M. Schrenk, I. Bure, P. Jandaghi, J.D. Hoheisel, German Cancer Research
Center, Heidelberg
P25 Subgenome fractionation of up to 12 samples using only one microarray for targeted
HT-sequencing
S. Kelkenberg-Schade, B. Haldemann, T. Fries, N. Wermke, German Cancer Research
Center, Heidelberg; A. Pfeufer, Helmholtz Center Munich; B. Meder, University of
Heidelberg; S. Wolf, B. Korn, M. Scharfenberger-Schmeer, German Cancer Research
Center, Heidelberg
P26 Simultaneous methyl binding domain (MBD) protein based DNA isolation and
serum-autoantibody testing from human blood serum
M. Wielscher, M. Hofner, C. Noehammer, A. Weinhäusel, AIT Austrian Institute of
Technology GmbH, Vienna/A
P27 CpG methylation microarray elucidates DNA methylation changes in cell cultures
A. Weinhaeusel, AIT Austrian Institute of Technology GmbH, Vienna/A; W. Mikulits,
Medical University of Vienna/A; M. Hofner, W. Pulverer, R. Pichler, K. Vierlinger,
C. Noehammer, AIT Austrian Institute of Technology GmbH, Vienna/A
P28 Optimization of fluorescence signals on rolling circle amplification-enhanced
microarrays
L. Linck, BAM Federal Institute for Materials Research and Testing, Berlin; E. Reiß,
F. Bier, Fraunhofer IBMT, Potsdam; J. Sobek, Functional Genomics Center Zurich/CH;
U. Resch-Genger, BAM Federal Institute for Materials Research and Testing, Berlin
P29 Aptamers enable the differentiation of indoor moulds
C. Reinemann, J.-F. Ducroz, A. Müller, B. Strehlitz, Helmholtz Centre for Environmental
Research GmbH - UFZ, Leipzig
P30 CountBases - a bioinformatic platform for next-generation transcriptome analyses
S. Lorenz, C. Grumaz, S. Rupp, K. Sohn, Fraunhofer IGB, Stuttgart
P31 Aptamer-microarrays: reverse and sandwich formate
M. Lübbecke, J.-G. Walter, F. Stahl, T. Scheper, Leibniz Universität Hannover
P32 Screening of aptamers for analytical applications via microarrays
J.-G. Walter, M. Lübbecke, G. Zhu, F. Stahl, T. Scheper, Leibniz Universität Hannover
P33 Integrated genomic profiling for improved sub-classification of aggressive b-cell
lymphoma based on a universal array platform
S. Weishaupt, University of Stuttgart; J.D. Hoheisel, German Cancer Research Center,
Heidelberg; C. Thorns, H. Merz, University of Schleswig-Holstein, Lübeck; N.C. Hauser,
K. Lemuth, S. Rupp, Fraunhofer IGB, Stuttgart
P34 A step towards an improved diagnosis of prostate cancer in patients with elevated
PSA levels
S. Rimmele, NMI Natural and Medical Sciences Institute at the University of Tuebingen,
Reutlingen; A. Lüking, A. Höpfner, P. Schulz-Knappe, Protagen AG, Dortmund; T. Joos,
N. Schneiderhan-Marra, NMI Natural and Medical Sciences Institute at the University of
Tuebingen, Reutlingen
P35 A polymer hydrogel immobilization technique for attachment of DNA molecules in
microfluidic structures
F. Scherag, University of Freiburg; C. Carstens, Laborpraxis Elbracht, Naumburg;
N. Hlawatsch, microfluidic ChipShop GmbH, Jena; T. Brandstetter, J. Rühe, University of
Freiburg
P36 XworX - next generation data analysis framework
A. Kriegner, A. Yildiz, E. Dilaveroglu, I. Visne, K. Vierlinger, A. Weinhaeusel,
C. Noehammer, AIT Austrian Institute of Technology GmbH, Vienna/A
P37 Stability analysis of marker selection techniques for high-dimensional biological data
L. Lausser, University Hospital Ulm; C. Müssel, University of Ulm; M. Markus, University
Hospital Ulm; H.A. Kestler, University of Ulm & University Hospital Ulm
P38 Tiling array analysis of the small RNA fraction of the microbial amino acid producer
Corynebacterium glutamicum
J. Pahlke, N. Dobler, Forschungszentrum Jülich GmbH; C. Hafemeister, MPI for
Molecular Genetics, Berlin; A. Schliep, University of New Jersey, Rutgers, NJ/USA; M. Bott,
T. Polen, Forschungszentrum Jülich GmbH
P39 On chip PCR products for in situ protein expression
S. Syafrizayanti, C. Di, M. Fugazza, J.D. Hoheisel, German Cancer Research Center,
Heidelberg
P40 Functional genomics for regenerative medicine: optimization of stem cells in live cell
chips
C. Maercker, Mannheim University of Applied Sciences; K. Bieback, I. Brinkmann,
University of Heidelberg, Mannheim; D. Breitkreutz, M. Angstmann, Mannheim University
of Applied Sciences
P41 Functional 3D-surfaces for "everyone"
C. Heise, U. Schedler, PolyAn GmbH, Berlin
P42 Characterization of novel epi-mutations in breast cancer with respect to their potential
contribution to an epigenetic field defect
Y. Riazalhosseini, A. Moghaddas Gholami, German Cancer Research Center, Heidelberg;
M. Malekpour, Tehran University of Medical Sciences/IR; S. Kumar Botla, A. Jahangiri
Babadi, German Cancer Research Center, Heidelberg; V. Bubnov, Odessa State Medical
University/UA; H. Najmabadi, University of Social Welfare and Rehabilitation Sciences,
Tehran/IR; J.D. Hoheisel, German Cancer Research Center, Heidelberg
P43 Pathogenicity related genes among the Streptomyces species causing potato scab
diseases group
G. Khodakaramian, Bu - Ali Sina University, Hamedan/IR
P44 Segmentation of tumor tissue in gray medical images using watershed
transformation method
S.D.S. Al-Shaikhli, A.A.M. Bahrani, University of Baghdad/IRQ
LMP01 Lack of beta1 integrin results in hemivertebrae development in mice
S. Guo, S. Wynn, T. Au, D. Chan, The University of Hong Kong/PRC; A. Aszodi, R. Fassler,
MPI of Biochemistry, Martinsried; K. Cheah, The University of Hong Kong/PRC
LMP02 Large scale RNAi screen to identify synthetic lethal partners of DNA-PKCS in
pancreatic cancer
J. Fredebohm, M. Böttcher, J.D. Hoheisel, German Cancer Research Center, Heidelberg
LMP03 Highly sensitive detection of microRNA and mRNA from FFPE tissue and blood
samples by expression microarray
H. Sudo, S. Takizawa, Y. Ueda, T. Kuroda, M. Ichikawa, O. Nomura, H. Akiyama,
H. Nobumasa, Toray Industries, Inc., Kanagawa/J
LMP04 Robust and reproducible automated tissue homogenization
C. Poggel, T. Adams, A. Langhammer, A. Bosio, Miltenyi Biotec GmbH, Bergisch
Gladbach
LMP05 Lab-on-chip based mulitparameter analysis for point-of-care testing
E. Ehrentreich-Förster, Fraunhofer IBMT, Potsdam; S. Schumacher, K. Wunderlich,
University of Potsdam; D. Michel, F. Bier, Fraunhofer IBMT, Potsdam
LMP06 In situ protein tagging for proteome analysis in mouse embryonic stem cells
F. Schnütgen, F. Ehrmann, University of Frankfurt Medical School; I. Poser, MPI for
Molecular Cell Biology and Genetics, Dresden; N. Hubner, MPI of Biochemistry,
Martinsried; T. Floss, W. Wurst, Helmholtz Center München, Neuherberg; T. Hyman,
MPI for Molecular Cell Biology and Genetics, Dresden; M. Mann, MPI of Biochemistry,
Martinsried; H. von Melchner, University of Frankfurt Medical School
LMP07 Protease profiling with reporter peptides for tumor diagnosis
A. Jacob, M. Dauber, German Cancer Research Center & Peps4LS, Heidelberg;
J.D. Hoheisel, German Cancer Research Center, Heidelberg; R. Hofheinz, D. Yepes,
V. Costina, M. Neumaier, P. Findeisen, University Hospital Mannheim
LMP08 Epigenetically deregulated microRNA-375 enhances Estrogen Receptor α activity in
breast cancer
P. de Souza Rocha Simonini, A. Breiling, N. Gupta, German Cancer Research Center,
Heidelberg; M. Malekpour, Tehran University of Medical Sciences/IR; M. Youns, German
Cancer Research Center, Heidelberg; R. Omranipour, Tehran University of Medical
Sciences/IR; F. Malekpour, Shahid Beheshti University of Medical Sciences, Tehran/IR;
S. Volinia, University of Ferrara/I; C.M. Croce, The Ohio State University, Columbus,
OH/USA; H. Najmabadi, University of Social Welfare and Rehabilitation, Tehran/IR;
S. Diederichs, Ö. Sahin, D. Mayer, F. Lyko, J.D. Hoheisel, Y. Riazalhosseini, German
Cancer Research Center, Heidelberg
LMP09 Production of protein microarrays by cell-free in situ expression
M. Fugazza, J.D. Hoheisel, German Cancer Research Centre, Heidelberg