Thursday, 12 November 2015 | |
10.00 | Welcome and Introductory Remarks |
W. Beckmann, Bayer Technology Service, Leverkusen/D | |
set the theme | |
10.10 | Following the particles on their journey from crystallizer to patient |
C. Price, University of Strathclyde, Glasgow/UK | |
Multiplicity of solid state forms design the form |
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11.10 | Selection of solid-state forms for new chemical entities: challenges, opportunities and lessons learned |
C. Saal, Merck KGaA, Darmstadt/D | |
12.00 | Hydrate phases in pharmaceutical development |
B. Baumgartner, Sanofi-Aventis Deutschland GmbH, Frankfurt/D | |
12.50 | Lunch Break |
Scientific aspects of solid-state engineering design the particle |
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14.00 | Polymorphism and solvate formation – potential threats in pharmaceutical industry |
D. Wieckhusen, Novartis Pharma AG, Basel/CH | |
14.50 | The role of API surface chemistry in pharmaceutical processes |
J. Heng, Imperial College London/UK | |
15.40 | Solid form design & crystal habit modification: utilizing crystallographic data to guide experimental design |
S. Chan, Novartis Pharma AG, Basel/CH | |
16.30 | Coffee Break |
Molecular modelling aspects of materials science support via modelling |
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16.50 | Exploring solid forms landscapes with structural informatics |
N. Feeder, CCDC, Cambridge/UK | |
17.40 | Solvate formation and assessment of crystallizability and assessment of stability of amorphous materials |
A. Florence, CMAC - University of Strathclyde, Glasgow/UK | |
18.30 | End-of-day-1 |
20.00 |
Conference Dinner at the historical Restaurant "Gerbermuehle", Gerbermuehlstrasse 105, 60594 Frankfurt |
Friday, 13 November 2015 | |
Formulation aspects of material science and engineering – Control of the API physical form secure the API attributes |
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08.30 | Integrated crystal and particle engineering for developing pharmaceutical tablet |
C. Sun, University of Minnesota, Minneapolis, MN/USA | |
09.20 | The role of particle engineering in formulation design – Link between drug substance and drug product |
R.A. Storey, AstraZeneca R&D, Macclesfield/UK | |
10.10 | Coffee Break |
paneled discussion | |
10.30 | Current topics of material science engineering in drug development and manufacturing |
J.-O. Henck – C. Price – W. Beckmann – B. Baumgartner | |
12.00 | Lunch Break |
Material science aspects of solid-solutions of API’s amorphous materials |
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13.00 | Amorphous organic materials |
L. Yu, University of Wisconsin, Madison, WI/USA | |
13.50 | Industrial perspectives of manufacturing solid dispersions as enabling technology – From early development to commercial manufacturing |
G. Verreck, Johnson & Johnson Pharma R&D, Beerse/B | |
14.40 | Coffee Break |
Control strategies of solid state form API attributes in formulation performance impact on product |
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15.00 | Small-scale approaches for supporting the solid form selection |
J. Rantanen, University of Copenhagen/DK | |
15.50 | What are the critical attributes of APIs which influences formulation microstructure and dominates product functionality ? |
R. Price, University of Bath/UK | |
16.40 | Connecting the API solid form and particle to drug product performance |
M. Ticehurst, Pfizer, Canterbury/UK | |
17.30 | End and farewell |