Tuesday, 19 April 2016
Wednesday, 20 April, 2016
Thursday, 21 April 2016
| 10:00 |
Registration |
|---|---|
| 11:00 | Welcome Address |
Imaging organotypic model systemsChair: U. Marx, Technical University of Berlin/D |
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| 11:05 | Keynote Lecture
Three dimensional imaging in living human lung tissue S. Hippenstiel, Charité - Universitätsmedizin Berlin/D |
| 11:50 |
Development of a 3D Human organotypic lung tumor model with 18F-FDG PET as a non-destructive read-out D. Fecher¹; T. Schwarz²; S. Nietzer¹; G. Dandekar²; H. Walles¹; K. Lückerath³; ¹ University Hospital Würzburg, Translational Center Würzburg and Fraunhofer IGB, Würzburg/D; ² Translational Center Würzburg, Fraunhofer IGB and University Hospital Würzburg/D; ³ University Hospital Würzburg/D |
| 12:10 | 3D culture models of vasculogenesis and sprouting angiogenesis for automated analysis in multiwell plates l. Muller¹ ¹ CIRB - INSERM, Paris/F |
| 12:30 | Lunch / Poster / Exhibition |
Advanced bioprinting for complex tissue modelsChair: U. Graf-Hausner, Zurich University of Applied Science, Wädenswil/CH |
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| 14:00 |
Keynote Lecture High resolution bioprinting to deal with tissue complexity F. Guillemot, Poietis, Pessac/F |
| 14:45 |
Bioprinted tissues for substance testing M. Rimann¹; S. Laternser¹; E. Bono¹; M. Nosswitz¹; H. Keller²; O. Leupin²; ¹ Zurich University of Applied Sciences, Waedenswil/CH; ² Novartis Institutes of Biomedical Research, Basel/CH; ³ University of Zurich/CH |
| 15:05 |
Universal lab-on-a-chip platform for complex, perfused 3D tissues generated by 3D printing F. Sonntag¹; J. Ströbel¹; S. Grünzner¹; M. Busek¹; U. Klotzbach¹; F. Schmieder¹ ¹ Fraunhofer Institute of Material and Beam Technology IWS, Dresden/D |
| 15:25 |
Immediate drop on demand technology – generating 3D-Cell Culture Models L. Schober¹; C. Laske¹; I. Schuster²; T. Brode¹; A. Traube¹; A. Traube¹ ¹ Fraunhofer IPA, Stuttgart/D; ² University of Stuttgart/D |
| 15:45 |
Coffee Break |
Strategies for high-throughput screening and analysisChair: J. Kelm, InSphero AG, Schlieren/CH |
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| 16:15 |
Phenotypic screening of autophagy modulating drugs in a three dimensional human brain cancer model by light sheet-based fluorescence microscopy: A new perspective in drug discovery N. Ansari¹; F. Pampaloni¹; K. Kabat vel Job¹; E. H.K. Stelzer¹ ¹ Goethe University Frankfurt/D |
| 16:35 |
High throughput screenings of live cells in 2D and 3D environments based on superhydrophilic-superhydrophobic surface patterning P. Levkin¹; A. Popova²; I. Neto²; K. Demir² ¹ Karlsruhe Institute of Technology (KIT), Eggenstein-Leopoldshafen/D; ² Karlsruhe Institute of Technology (KIT), Karlsruhe/D |
| 16:55 |
High-throughput microfluidic platform for culture of 3D kidney tissue models H. Lanz¹; M. Vormann¹; A. van den Heuvel¹; K. Wilschut¹; C. Ping¹; R. van Vught¹; ¹ Mimetas, Leiden/NL |
| 17:15 |
Keynote Lecture Comprehensive molecular profiling of organoids and patient tissue in the context of toxicogenomics R. Schlapbach, ETH Zurich/CH |
| 18:00 | End of Lecture Programme of Day 1 |
| 18:15 - 19:15 |
Section Member Assembly
DECHEMA Sections " Cell Culture Technology" and "Medical Biotechnology" |
| 18:00 - 21:00 |
Poster Session / Poster Party |
Understanding cancer development and progressionChair: C. Burger, Merck KGaA, Darmstadt/D |
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| 09:00 | Keynote Lecture
Modelling Wnt signalling in 3D culture T. Dale, Cardiff University/UK |
| 09:45 |
A novel culture strategy to model tumour microenvironment dynamics and study tumour-stroma interactions and disease progression M. Estrada¹; S. Rebelo¹; V. Santo¹; S. Abreu¹; E. Davies²; M. Pinto³; H. Pereira⁴; ¹ iBET/ITQBAX-UNL, Oeiras/P; ² Bioscience, Oncology iMed, AstraZeneca, Chesire/UK; ³ Institute of Molecular Pathology and Immunology, Porto/P; ⁴ Instituto Gulbenkian de Ciência, Oeiras/P; 5 European Cancer Stem Cell Institute, Cardiff/UK; 6 Boehringer Ingelheim, Vienna/A |
| 10:05 | Establishment of a standardized 3D in vitro tumor-stroma model
M. Mueller¹; S. Hensler¹; B. Kotkamp¹; K. Pohl²; N. Linde³; D. Stoll⁴ ¹ Hochschule Furtwangen, Villingen-Schwenningen/D; ² NMI Reutlingen/D; ³ Mount Sinai School of Medicine, New York/USA; ⁴ Hochschule Albstadt-Sigmaringen/D |
| 10:25 | Coffee Break |
Advanced models for substance testing: cancer therapyChair: T. Noll, University of Bielefeld/D |
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| 11:00 | The Spheroid microtumor model is predictive for the therapeutic response in neoadjuvant breast cancer (SpheroNEO study)
K. Halfter¹; N. Ditsch²; B. Mayer³ ¹ SpheroTec GmbH, Munich/D; ² Frauenklinik, Klinikum Großhadern, Munich/D; |
| 11:20 | Multi-parametric 3D tumor microtissue-based phenotypic compound classification
J. Kelm¹; Z. Weydert¹; M. Lal²; L. Mathews Griner²; C. Schmees³; B. Gierke³; ¹ Insphero AG, Schlieren/CH; ² NCATS/NIH, Rockville/USA; ³ NMI Technologietransfer GmbH, Reutlingen/D; ⁴ RWTH Aachen University/D |
| 11:40 |
Conditionally immortalized human endothelial cells for the investigation of KSHV latency and intervention in novel in vitro and in vivo models T. Dubich¹; C. Lipps¹; M. Butueva¹; T. May²; D. Wirth¹ ¹ Helmholtz Centre for Infection Research, Braunschweig/D; ² InSCREENeX GmbH, Braunschweig/D |
| 12:00 |
Lunch / Poster / Exhibition |
From the potential of organoids to multi-organ platformsChair: T. May, InSCREENeX GmbH, Braunschweig/D |
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| 14:00 |
Keynote Lecture Organoids: An in vitro culture for all patients R. Vries, foundation Hubrecht Organoid Technology, Utrecht/NL |
| 14:45 |
Emulating the human vasculature in a multi-organ-chip platform T. Hasenberg¹; K. Schimek²; S. Mühleder³; A. Dotzler¹; S. Bauer²; K. Labuda3; ¹ TissUse GmbH, Berlin/D; ² Technische Universität Berlin/D; ³ Austrian Cluster for Tissue Regeneration, Vienna/A |
| 15:05 |
Adding metabolic competence to 3D spheroid-based assays by using a microfluidic multi-tissue culturing platform O. Frey¹; J. Kim¹; A. Hierlemann¹; D. Fluri²; J. Kelm²; T. Petreus³; E. Tang³; ¹ ETH Zürich, Basel/CH; ² InSphero, Schlieren/CH; ³ AstraZeneca, Cheshire/UK; |
| 15:25 |
Coffee Break |
Assays and devicesChair: M. Rimann, Zurich University of Applied Science, Wädenswil/CH |
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| 16:00 |
Immortalized lung epithelial cells with in vivo like characteristics T. May¹; T. Herfurth¹; R. Schucht¹ ¹ InSCREENeX GmbH, Braunschweig/D |
| 16:20 |
Designing assays and appropriate controls to interrogate 3D culture models T. Riss¹ ¹ Promega Corporation, Madison/USA |
| 16:40 |
The Nunclon Sphera surface supports formation of three dimensional cancer spheroids in suspension P. Reuter¹; C. Neeley²; L. Gaarn² ¹ Thermo Fisher Scientific, Langenselbold/D; ² Thermo Fisher Scientific, Rochester/USA |
Advanced model systems: brain
Chair: M. Rimann, Zurich University of Applied Science, Wädenswil/CH |
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| 17:00 |
Keynote Lecture Modelling human neuronal maturation in 3D I. Galimberti, Novartis Pharma AG, Basel/CH |
| 17:45 | End of lecture programme of Day 2 |
| 19:00 | Conference Dinner, Historisches Kaufhaus |
Advanced model systems: from heart to brainChair: H. Hauser, Helmholtz Centre for Infection Research, Braunschweig/D |
|
| 09:00 | Keynote Lecture
Engineered human myocardium for drug screening applications W.-H. Zimmermann, University Medical Center Göttingen/D |
| 09:45 |
Intestinal organoids for functional studies on nutrient transport, sensing and incretin hormone secretion T. Zietek¹; E. Rath¹; D. Haller¹; H. Daniel¹ ¹ Technische Universität München, Freising/D |
| 10:05 |
A 3D human co-culture microtissue model for nanoparticle effect and uptake studies at the placental barrier C. Muoth¹; L. Diener¹; W. Jochum²; P. Wick¹; T. Buerki-Thurnherr¹ ¹ Empa, St. Gallen/CH; ² Cantonal Hospital, St. Gallen/CH |
| 10:25 |
Differentiation of human pluripotent stem cells into definitive endoderm cells in a flexible three-dimensional cell culturing matrix R. Harjumäki¹; A. Taalas¹; L. Kanninen¹; J. Niklander¹; M. Yliperttula¹; Y. Lou¹ ¹ University of Helsinki, Helsinki/FIN |
| 10:45 |
Human pluripotent stem cell-based in vitro neural tissues and disease models for the chemical and pharmaceutical industry M. Baquie¹; E. Eggermann²; A. Roux²; G. Fischler²; Z. Nayernia³; E. Cosset³; ¹ NEURIX, Plan-les-Ouates/CH; ² HEPIA University of Applied Sciences, Geneva/CH; ³ University and Hospitals of Geneva/CH |
| 11:05 |
Coffee Break |
Advanced model systems: skin in vitroChair: H. Hauser, Helmholtz Centre for Infection Research, Braunschweig/D |
|
| 11:35 | Keynote Lecture
Cosmetic substance testing – from static single skin cultures towards dynamic co-culture with human immunity or liver equivalents J. Kühnl, Beiersdorf AG, Hamburg/D |
| 12:10 |
Functionalized electrospun nanofibers for the development of a three-dimensional skin model A. Rossi¹; J. Groll1; H. Walles2 ¹ University Hospital Würzburg/D;2 University Hospital Würzburg and Fraunhofer IGB, Würzburg/D |
| 12:30 | Impedance Spectroscopy: A new tool to characterize reconstructed human epidermis
F. Groeber¹, L. Engelhardt2; H. Walles3; J. Hansmann3 ¹ Fraunhofer IGB, Würzburg/D; 2 University of Würzburg/D; 3 University of Würzburg and Fraunhofer IGB, Würzburg/D |
| 12:50 | Lunch / Poster / Exhibition |
Advanced model systems: osteoarthritis and bone repairChair: R. Pörtner, Hamburg University of Technology/D |
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| 13:50 |
Porcine chondrocyte micromasses – a model for osteoarthritis? T. Dehne¹; N. Schlichting¹; K. Mans¹; M. Endres²; B. Stuhlmüller¹; C. Kaps²; ¹ Charite Universitätsmedizin Berlin/D; ² TransTissue Technologies, Berlin/D |
| 14:10 |
Evaluation of structure parameters for development of patient-matched 3D porous titanium bone implants L. Zumofen1; K. Kopanska2; A. Kirchheim1; E. de Haller3; U. Graf-Hausner2 1 Zurich University of Applied Sciences, Winterthur/CH; 2 Zurich University of Applied Sciences, Wädenswil/CH; 3 -, - |
| 14:30 |
Chondrogenic microtissues in the lab & for the clinic M. Lehmann¹; F. Voss¹; F. Martin¹; P. Schläger¹; U. Anderer¹ ¹ Brandenburgische Technische Universität Cottbus-Senftenberg, Senftenberg/D |
| 14:50 |
Closing remarks |
| 15:00 | End of the conference |