Sunday, 10 May 2015 | |
19.30 h | Pre Conference Dinner at the Hotel Restaurant (venue) Special Buffet 16 Euro (Selfpayment) |
Monday, 11 May 2015 | |
08:20 h | Opening |
R. Takors, Universität Stuttgart / W. Blümke, Evonik Industries AG, Hanau/D | |
08.30 h | Keynote |
Scale-up considerations for economic processes in biotechnology | |
B. König, BioInvent Berlin GmbH & Sandoz Industrial Products GmbH/D | |
Application of scale-up and scale-down criteria | |
09.15 h | Scale down strategies of cell culture processes |
C. Klinger, C. Schmidberger, D. Eisenkraetzer, Roche Diagnostics GmbH, Penzberg/D | |
09.45 h | Scaling immunoconjugation reactors from lab to clinical manufacturing |
H. Brod, J. Kauling, M. Jenne, V. Michele, Bayer Technology Services GmbH, Leverkusen/D | |
10:15 h | Coffee Break |
Behaviour of biological systems in different scales | |
10.45 h |
Response of Corynebacterium glutamicum to oscillating oxygen and substrate availability in a novel three-compartment scale-down bioreactor |
A. Lemoine, N. Maya, R. Spann, P. Neubauer, S. Junne, TU Berlin/D | |
11.15 h | Experimental analysis of scale-up dependent regulatory phenomena |
M. Löffler, J. Simen, A. Feund, Universität Stuttgart/D; G. Jäger, Universität Tübingen/D; R. Takors, Universität Stuttgart/D | |
11.45 h | Coffee Break |
Novel reactor concepts for scale-down/scale-up | |
12.15 h | Scale-up compatible mini-HGMS-system for gluconic acid production with magnetizable gold-nanoparticles |
T. Hering, R. Ulber, N. Tippkötter, TU Kaiserslautern/D | |
12.45 h | cGMP compliant upscale of a moss-based photoautotrophic α-galactosidase production process |
H. Niederkrüger, A. Busch, A. Schaaf, T. Frischmuth, greenovation Biotech GmbH, Freiburg/D; C. Koch, T. Pultar, Biomeva GmbH, Heidelberg/D | |
13.15 h | Lunch Break |
Novel reactor concepts for scale-down/scale-up |
14.15 h | The challenge of scaling up photobioreactors - approaches in a small scale for microalgae |
M.L. Socher, F. Krujatz, T. Bley, J. Weber, J. Steingroewer, C. Löser, TU Dresden/D | |
14.45 h | Single-cell bioreactors: cutting edge cultivation devices for the ultimate scale-down of bioprocesses |
A. Grünberger, C. Probst, W. Wiechert, D. Kohlheyer, Forschungszentrum Jülich GmbH/D | |
15.15 h | Scale-up and down of a next generation bioreactor system for high-density animal cell culture: 5 mL - 2500 L |
M. De Jesus, ExcellGene SA, Monthey/CH; M. Kühner, Kühner AG, Birsfelden/CH; F. Wurm, Swiss Federal Institute of Technology Lausanne (EPFL)/CH | |
15.45 h | Coffee Break |
Computational tools for scale-up and scale-down | |
16.15 h | Computation-driven scale-down of fermentation |
W. Van Winden, A. Deshmukh, DSM Biotechnology Center, Delft/NL; W. Van Gulik, S. Heijnen, R. Mudde, C. Haringa, TU Delft/NL; M. Reuss, Universität Stuttgart/D; J. Chu, J. Xia, W. Tang, East China University of Science and Technology, Shanghai/CHN; H. Noorman, DSM Biotechnology Center, Delft/NL | |
16.45 h | How can computational fluid dynamics be used in order to rapidly expand bone-marrow derived hMSCs in clinically relevant numbers? |
V. Jossen, A. Ott, Zurich University of Applied Sciences, Wädenswil/CH; C. van den Bos, Lonza Cologne GmbH/D; D. Eibl, R. Eibl, Zurich University of Applied Sciences, Wädenswil/CH | |
17.15 h | Computational fluid dynamics (CFD) as a tool to improve scale-up and scale-down of processes in the pharmaceutical industry |
T. Wucherpfennig, J-E. Schaefer, M. Berger, Boehringer Ingelheim Pharma GmbH & Co. KG, Biberach an der Riss/D | |
17:45 h | Meeting of the working party "Bioprozesstechnik" |
17:45 - 19:45 h | Poster Party with Beer and Brezel |
Tuesday, 12 May 2015 | |
08.30 h |
Stirred, not shaken; unsolved issues and new problems in scale-down for scale-up. |
A. Nienow, University of Birmingham/UK | |
Industrial scale up and scale down case studies | |
09.15 h | Down-scaled process development for the production of viral vaccines at high cell-densities |
D. Vazquez, Y. Genzel, Max-Planck-Institut für Dynamik komplexer technischer Systeme, Magdeburg/D; M. von Stosch, Universidade Nova de Lisboa/P; I. Jordan, V. Sandig, ProBioGen AG, Berlin/D; U. Reichl, Max-Planck-Institut für Dynamik komplexer technischer Systeme, Magdeburg/D | |
09.45 h | Speed-up your scale-up - from clinic to commercial manufacturing |
T. Peuker, Sartorius Stedim Systems GmbH, Guxhagen/D | |
10.15 h | Coffee Break |
Industrial scale up and scale down case studies | |
10.45 hr | Industrial scale-up of a co-digestion plant |
Th. Bayer, Infraserv GmbH & Co. Höchst KG, Frankfurt/D | |
11.15 h | Getting small for understanding the big - Scale-down model qualification and use in process characterization |
K. Kaiser, Bayer Pharma AG, Wuppertal/D | |
11.45 h | SDM in industrial cell culture processes - a powerful tool to ensure reliable production in the light of raw material lot-to-lot variations |
M. Jenzsch, M. Kunze, H. Tebbe, Roche Diagnostics GmbH, Penzberg/D | |
12.15 h | Lunch Break |
Scale-down/scale-up of DSP processes | |
13.15 h | Scale-up of gassing crystallization processes with respect to an optimal product quality |
T. Kleetz, G. Schembecker, K. Wohlgemuth, TU Dortmund/D |
13.45 h | Integration of ATPE and precipitation in the downstream processing of monoclonal antibodies from lab scale to production scale |
T. Wellsandt, P. Gronemeyer, J. Strube, TU Clausthal/D | |
14.15 h | Coffee Break |
Scale-down/scale-up of DSP processes | |
14.45 h | Optimization of multimodal chromatography in down-scale process development |
J. Paul, M. Meyer, C. Braemer, S. Jensen, G. Cornelissen, Hochschule für Angewandte Wissenschaften Hamburg/D | |
15.15 h | SPTFF - process development and scale up |
T. Bisschop, Merck Chemicals GmbH - Merck Millipore, Schwalbach/D | |
15.45 h | Coffee Break |
Open Topic | |
16.15 h | Oxyfunctionalization of terpene substrates using fungal enzymes |
R. Leonhardt, T. Seibel, J. Kolwek, U. Krings, R.G. Berger, Universität Hannover/D | |
16.45 h | Morphology engineering of Streptomyces griseus |
J. Moench-Tegeder, R. Krull, TU Braunschweig/D | |
18.00 h | Conference Dinner - Dinner Cruise Meeting point: Landing stage in front of the hotel |
Wednesday, 13 May 2015 | |
08.30 h | Posterpresentation - 3 Best Poster |
Open Topic | |
09.00 h | Understanding and engineering of Clostridium pasteurianum for new microbial production processes |
W. Sabra, C. Groeger, W. Wang, TU Hamburg-Harburg/D; T. Krieg, D. Holtmann, DECHEMA Forschungsinstitut, Frankfurt/D; R. Reddy-Bommareddy, S. Rappert, A.-P. Zeng, TU Hamburg-Harburg/D | |
09.30 h | Online fluorescence spectroscopy combined with light-induced gene expression in a high-throughput screening system |
G. Wandrey, K. Hoffmann, RWTH Aachen/D; C. Bier, D. Binder, J. Pietruszka, T. Drepper, K.E. Jaeger, Universität Düsseldorf/D; J. Büchs, RWTH Aachen/D | |
10.00 h | Rapid monitoring of biotin-blocked binding sites of streptavidin during fermentation |
J. Müller, J. Risse, K. Friehs, Universität Bielefeld/D |
|
10.30 h | Coffee Break |
Open Topic | |
11.00 h | New minimal cells for enzymatic synthesis |
I. Sührer, TU München, Garching b. München/D; W. Lubitz, BIRD-C GmbH, Wien/A; D. Weuster-Botz, K. Castiglione, TU München, Garching b. München/D | |
11.30 h | Applications of FTIR spectroscopy for online process analytics |
A. Boos, D. Sellin, J. Fagaschewski, S. Baum, G.M. Shibabaw, S. Bohne, L. Hilterhaus, H.K. Trieu, A. Liese, TU Hamburg-Harburg/D | |
12.00 h | Optimization of hetero- and mixotrophic cultivation of the red alga Galdieria sulphuraria using glycerol as a carbon source |
P. Schwerna, J. Wolf, F. Katzschmann, R. Buchholz, S. Stute, Universität Erlangen-Nürnberg/D | |
12.30 h | Closing |