| Chemical biology of natural products | |
|---|---|
| P 1.01 | Labyrinthopeptins – new lantibiotics with broad anti-viral activity H. Prochnow¹; S. Birudukota1,S. Blockus²; S. Gordts4, S. Haid²; T. Pietschmann²; T. Schulz³; D. Schols⁴; M. Brönstrup1 ¹ Helmholtz Centre for Infection Research, Braunschweig/D; ² TWINCORE, Centre for Experimental and Clinical Infection Research GmbH, Hannover/D; ³ Hannover Medical School/D; German Center for Infection Research (DZIF), Hannover/D; ⁴ University of Leuven/B |
| P 1.02 | Synthetic strategy towards cystobactamid analogs G. Testolin¹; H. Prochnow¹; M. Brönstrup¹ ¹ Helmholtz Centre for Infection Research, Braunschweig/D |
| P 1.03 | Synthesis of natural products from entomophatogenic bacteria and their fluorescent analogs for use in visual imaging F. Wesche¹; H. Adihou1; H. Bode1 ² University of Frankfurt/D |
| P 1.04 | MS-based structure and biosynthesis elucidation of stackepeptins – supersized class III lanthipeptides N. Jungmann¹; E. van Herwerden¹; M. Hügelland¹; R. Süssmuth¹ ¹ TU Berlin /D |
| P 1.05 | A fluorogenic dye-based system for monitoring bacterial compound uptake V. Fetz¹; K. Ferreira¹; H. Hu²; M. Brönstrup¹ ¹ Helmholtz Centre for Infection Research, Braunschweig/D; ² Institute of Materia Medica, Beijing/CN |
| P 1.06 | From insects to hydrozoa: communication strategies in microbe-host interactions C. Beemelmanns¹ ¹ Hans-Knöll-Institut Jena/D |
| P 1.07 | Blending chemoproteomics and structural biology - the discovery of a selective EphA2 inhibitor S. Heinzlmeir¹; G. Médard²; D. Kudlinzki³; S. Gande³; V. Linhard³; K. Saxena³; J. Lohse²; T. Treiber²; H. Schwalbe³; B. Kuster¹ ¹ DKTK Munich and TU München, Freising/D; ² TU München/D; ³ DKTK Frankfurt and University of Frankfurt/D |
| P 1.08 |
Guideline for reprogramming non-ribosomal peptide synthetases K. Bozhüyük¹; F. Fleischhacker1 ¹ Goethe-Universität Frankfurt am Main/D |
| P 1.09 |
Understanding iterative nonribosomal peptide synthetases from Xenorhabdus KJ12.1 S. Nowak¹ ¹ Goethe-Universität Frankfurt am Main/D |
| Phenotypic Screening | |
| P 2.01 | Phenotypic screening with Ras-FRET biosensors identifies cancer stem cell inhibitors D. Abankwa¹ ¹ Åbo Akademi, Turku/FIN |
| P 2.02 | MALDI mass spectrometry imaging enables simultaneous measurement of donepezil distribution and its pharmacological efficacy in-Situ in rat brain S. Schulz¹; B. Meyer¹; J. Fuchser²; C. Hopf¹ ¹ University of Applied Sciences Mannheim/D; ² Bruker Daltonik GmbH, Bremen/D |
| P 2.03 |
Cell separation by small molecule - protein interaction using capture compounds T. Lenz¹; C. Dalhoff¹; M. Sefkow¹; M. Dreger¹; H. Köster¹ ¹ caprotec Bioanalytics GmbH, Berlin/D |
| P 2.04 |
Screening for inhibitors of the Escherichia coli outer membrane channel TolC S. Schrüfer¹; W. Tegge¹; M. Brönstrup¹; U. Bilitewski¹ ¹ Helmholtz-Zentrum für Infektionsforschung (HZI), Braunschweig/D |
| Protein-protein interaction | |
| P 3.01 |
Contact area extension defines the interaction specificity of conserved enzymatic subunits and unlinks two essential metabolic pathways F. Semmelmann¹ ¹ University of Regensburg/D |
| P 3.02 |
Exploring the molecular mechanism of viral interference R. Hoffmann¹; J. Schaubächer²; B. Schmidt²; J. Eichler¹ ¹ FAU Erlangen-Nürnberg, Erlangen/D; ² Universität Regensburg/D |
