In recent years, Advanced Therapy Medicinal Products (ATMP) have evolved into a promising and highly hoped-for medical approach to cure a broad spectrum of inherited and acquired human diseases, ranging from cancer to immunological disorders and rare diseases. However, the path from development to clinical application is not yet routine.
The conference will highlight the challenging field of gene and cell therapeutics.
Advances in development and manufacturing will be presented at ATMP 2022, as well as quality control methods and regulatory aspects: The focus is on the path to safe and beneficial advanced therapies for the patient.
The registration is open:
| 10:00 | Registration |
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| 11:00 | Welcome |
| Session: Innovative iPSC- and MSC-derived therapeutics Chair: Roland Wagner, Technical University Braunschweig |
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| 11:05 |
Keynote lecture: "Scalable generation of custom-made immune cells for innovative cell-based immunotherapies and industrial applications" Nico Lachmann, MHH Medizinische Hochschule Hannover |
| 11:45 |
"Process design considerations for hMSC-based products" Jan Barekzai; Florian Petry; Peter Czermak; Denise Salzig, |
| 12:05 |
Poster talk: "Biomimetic matrices enable highly defined isolation of functional mesenchymal stromal cells in xeno-/serum-free media" Kristina Thamm¹; Kristin Moebus²; Russel Towers²; Richard Wetzel¹; |
| 12:10 |
Short break |
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Session: Therapeutic exosomes |
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| 12:20 |
Keynote lecture: "Functional extracellular vesicles as new therapeutic modality – Exosomes’ Road to the clinic" Jens Gruber, Curexsys GmbH, Göttingen |
| 13:00 |
Poster talk: "Challenges and Solutions for Production of Therapeutic Exosomes" |
| 13:05 |
Lunch |
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Session: New approaches in cell-based therapies |
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| 14:00 |
Keynote lecture: "Engineering T cell receptors for adoptive cell therapy" Kilian Schober, Universitätsklinikum Erlangen |
| 14:40 |
"Cell-mediated visualization of local infections and drug delivery " Dagmar Wirth¹; Mario Köster¹; Sandhya Kumar¹; Peter Behrens²; Hansjörg Hauser¹; Andreas Kirschning³, ¹ Helmholtz Zentrum für Infektionsforschung mbH; ² Institute for Anorganic Chemistry; Leibniz University Hannover; ³ Institute for Organic Chemistry, Leibnitz University Hannover |
| 15:00 |
Keynote lecture: "Harnessing human 3D Cell Models to accelerate the development of advanced therapies" Catarina Brito, iBET & ITQB-NOVA, Oeiras/Portugal |
| 15:40 | Coffee break |
| Session: Tumor vaccines - strategies for personalisation and production Chair: Jessica Horbelt, Fraunhofer IPA, Stuttgart |
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| 16:15 |
Keynote lecture: "Application of mRNA technology in cancer therapy" Felicitas Müller, BioNTech SE, Mainz |
| 16:55 |
"Improved production strategies for oncolytic Measles virus as therapeutic Dustin Eckhardt; Denise Salzig; Peter Czermak, Technische Hochschule Mittelhessen |
| 17:15 | End of lecture programme of day 1 |
| 17:30 - 20:00 | Get Together / Poster Session |
| Session: Clinical ATMP application and manufacturing Chair: Andrea Traube, KyooBe Tech GmbH, Leinfelden-Echterdingen |
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| 09:00 |
Keynote lecture: "Home brewn CAR-T-Cell" Michael Schmitt, Uniklinik Heidelberg, Heidelberg |
| 09:40 |
"Running title: Modular mini-factories for the automated and scalable production of ATMPs" Andreas Traube; Jessica Horbelt; Martin Thoma; Natalie Gebken; Sarah Kleine-Wechelmann; Milena Frahm; Markus Schandar; Michael Klinger; Sebastian Puls; Rolf Wössner; Michael Pfeifer; Tobias Sauer, Fraunhofer IPA |
| 10:00 |
"Real laboratory for automated and digitalized ATMP production" Georg Popp¹; Rolf van Lengen²; Andreas Traube³; Karsten Seidl⁴; Carsten Claussen⁵; Michael Baßler⁶; Paul Franz¹; Anna Dünkel¹; Ulrike Köhl¹; Stephan Fricke¹, |
| 10:20 | Coffee break |
| Session: Innovative production strategies Chair: Anna Katharina Heide, RUHR-IP Patentanwälte, Essen |
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| 11:00 | Keynote lecture: "Single Cell Multi-Omics Driving the Future of Adoptive Cell Therapy" Andreas Schmidt, Singleron Biotechnologies GmbH, Köln/D |
| 11:40 | "AIDPATH – Modular Manufacturing Platform for AI-enabled hospital-based ATMP Production – A Concept Presentation" Frederik Erkens, Fraunhofer Institute for Production Technology IPT |
| 12:00 | Poster talk: "Fluidic imaging as PAT tool for cell aggregate monitoring" Martin Kraft, Bayer AG |
| 12:05 |
Keynote lecture: "Tackling the Challenges of AAV Vector Manufacturing" Nicole Faust, CEVEC Pharmaceuticals GmbH, Köln |
| 12:45 | Lunch |
| Session: From regulatory framework to clinical application Chair: Hansjörg Hauser, Helmholtz Centre for Infection Research, Braunschweig |
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| 13:30 |
"Risk Assessment – An intelligent tool for the evaluation of critical starting material" Claudia Papewalis¹; Marco Schmeer²; Martin Schleef², ¹ Valicare GmbH; |
| 13:50 |
"Plausibility of EP Patents - Post-filed experimental data as support of Anna Katharina Heide, RUHR-IP Patentanwälte, Essen |
| 14:10 |
"The current regulatory framework of ATMP storage and distribution – consequences and challenges " Andrea Zobel, World Courier |
| 14:30 | Coffee & Networking |
| 15:00 |
End of conference |
(as of 9 May 2022, subject to change)
The deadline for submitting presentations has passed. You can submit last minute posters on the following topics:
Please prepare 1-2 pages (incl. figures, max. size 1 MB, max. 2 pages).
You can use the Template to correctly format your contribution and upload it as PDF file.
Enter the author list (author and co-author/s) and affiliations in the same order as in your abstract.
Accepted abstracts will be published for all conference participants in a book of abstracts (PDF).
The conference language is English.
Please note: Registration fee cannot be waived for authors.
| Delegates | Members2) | Others |
|---|---|---|
| Industry | 630 | 645 |
| Academia | 420 | 435 |
| Students | 220 | 235 |
1) No VAT requested according to § 4.22 UStG, registration fee may include Business Package with VAT.
The prices remain valid even if it is necessary to switch to an online conference. The omission of catering costs will be compensated by higher technical, support and marketing costs as well as cancellation costs of the event center and the caterer.
2) Personal DECHEMA-, VDI-GVC-members and EFC/EFCE passport holders; personal VAAM members
The DECHEMA terms and conditions for conferences apply. Please note that the following informations are excerpts and supplements to the general terms and conditions.
Registration is possible, subject to capacity in the lecture rooms, up to the beginning of the conference. Confirmation of registration will be sent immediately by mail. The invoice, with payment confirmation, you will receive by post mail within two weeks.
The registration fees include conference ticket, book of abstracts and list of participants.
Editorial deadline for the list of participants is 30 April 2022.
Cancellations are only accepted in writing (i.e. by fax, surface mail or e-mail).
Please find details about cancellation dates and fees in the general terms and conditions. In case of no-show the conference fees won't be refunded and fees not yet paid still have to be paid.
The exhibition area is located in the foyer of the lecture hall and close to the catering area.
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ASEPTIC TECHNOLOGIES manufactures innovative aseptic production equipment, designed to provide safer & easier aseptic filling operations. The AT-Closed Vial® is provided ready to fill with its stopper secured in place, and sterilized by gamma irradiation. The filling is performed by a special needle piercing the stopper, which is then immediately heat-resealed by laser and capped. The drug product is thus never in contact with the environment. The AT-Closed Vial® ensures uncompromised Container Closure Integrity at -80°C and in vpLN2. |
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Barkey is a German family business for medical technology in the field of warming devices. The main goals: Preventing hypothermia and advancing Cell & Gene therapy research. For this purpose, Barkey produces dry temperature solutions for heating or thawing blood products, cell materials, infusion solutions, etc. The headquarters in Leopoldshöhe, Germany, the two locations in Boston, US and Shanghai, CN as well as a large distributor network enable the worldwide availability of the products. |
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Focusing on people and innovations, OLS OMNI Life Science accelerates research in life sciences and biotechnology with smart, reliable, and user-friendly technologies. Our products are found in laboratories of both the public and private sector, as well as laboratories of the pharmaceutical and biotechnology industries. The broad portfolio includes instruments for cell counting, cell culture, imaging, flow cytometry, and real rime cell analysis as well as media, reagents, consumables, services and consultation. This enables us to accompany you during the entire research process, from conception to conclusion. |
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PELOBIOTECH GmbH is a European supplier of reagents for biomedical research with a focus on primary cell culture. Choose from a portfolio of more than 20,000 products including primary cells, media and cell culture tools. For Extracellular Vesicle research and production we offer defined media optimized for mesenchymal stem cell culture and free of EVs, and some tools (defined coatings, cryo-preservation media & 3D Co-Culture Tools) optimized for Mesenchymal Stem/Stromal Cell research in this field. These reagents are available in R&D, GMP-like and GMP quality. Talk to us at the booth. |
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PeproTech creates the building blocks of your life science research by manufacturing high-quality products that advance scientific discovery and human health. Since 1988, we have grown into a global enterprise with state-of-the-art manufacturing facilities in the US, and offices around the world. With over 2,000 products, PeproTech has developed and refined innovative protocols to ensure quality, reliability and consistency. Our mission is to provide the highest quality products and premium support that address the needs and demands of today's scientists and researchers. We pride ourselves on being a trusted partner within the scientific community.
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denovoMATRIX designs and produces biomaterials, which address cell manufacturing challenges, enabling rapid growth rates of viable cells and meeting safety/ethical requirements of the industry. We are achieving this by employing our modular, biomimetic technology to functionalize cell culture ware as well as scaffolds as microcarriers. Our customers can apply our validated, ready-to-use products for isolation and expansion of MSC or expansion of iPSC in animal-component-free processes. We are further offering development service to create custom solutions with our clients. |
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RUHR IP Patent Attorneys located in Germany since 2006 represent their clients internationally and give advice with strategic vision, precisely focused on the client´s needs: with our excellently trained and experienced patent attorneys and our international and professionally diversified team. The needs of clients in the IP advisory environment have changed towards more comprehensive strategic and commercial advice. In particular, the support of SME, but also special cases, function more purposefully and efficiently with a flexible, medium-sized, integrated patent law firm. To this end, RUHR-IP offers agile and fast processes, professional expertise and a well-connected network in neighbouring areas of expertise. |
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Valicare, a daughter company of Syntegon Technology, is a GMP compliance service supplier, headquartered in Frankfurt am Main since 2002. Experienced senior GMP consultants, engineers and natural scientists support worldwide the pharma, biotech and medical device industry with GMP consulting, risk-based qualification and with validation of processes, systems and methods. Special competencies and services are offered for sterile filling (process development and validation of isolators) and for advanced therapy medicinal products (ATMP). Further information at www.valicare.com |
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Catarina Brito
Keynote lecture: „Harnessing human 3D Cell Models to accelerate the development of advanced therapies“
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Nicole Faust
Keynote lecture: "Tackling the Challenges of AAV Vector Manufacturing" |
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Jens Gruber
Keynote lecture: "Functional extracellular vesicles as new therapeutic modality – Exosomes’ Road to the clinic"
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Nico Lachmann
Keynote lecture: "Scalable generation of custom-made immune cells for innovative cell-based immunotherapies and industrial applications"
His statement: "Technical innovations along with stem cell technologies pave the way for the development of novel cells and ATMPs for innovative industrial applications and future immunotherapies, respectively." |
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Felicitas Müller
Keynote lecture: "Application of mRNA technology in cancer therapy" |
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Andreas Schmidt
Keynote lecture: "Single Cell Multi-Omics Driving the Future of Adoptive Cell Therapy"
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Michael Schmitt Keynote lecture: „Home brewn CAR-T-Cell“ |
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Kilian Schober (Universitätsklinikum Erlangen/D)
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The conference will highlight the challenging field of gene and cell therapeutic approaches, especially focusing on the following topics:
Ulf Bethke
Miltenyi Biotec GmbH, Bergisch Gladbach
Hansjörg Hauser
Helmholtz Centre for Infection Research, Braunschweig
Anna Katharina Heide
RUHR-IP, Essen
Jessica Horbelt
Fraunhofer IPA, Stuttgart
Cornelia Kasper
University of Natural Resources and Life Sciences, Vienna
Konrad Kohler
BioMedTech, Forschungscampus Reutlingen
Thomas Noll
University of Bielefeld
Ralf Pörtner
Technical University Hamburg
Denise Salzig
University of Applied Sciences Mittelhessen, Gießen
Bernd Schröder
Miltenyi Biotec GmbH, Teterow
Karin Tiemann
DECHEMA e.V., Frankfurt am Main
Andrea Traube
KyooBe Tech GmbH, Leinfelden-Echterdingen
Roland Wagner
Technical University Braunschweig
Dear lecture and poster authors, please note: Registration fee cannot be waived for authors.
Please use the online registration.
If you are unable to present your lecture for any reason, please let us know as soon as possible.
The official language of the conference is English. Simultaneous translation will be not available.
A video projector and a notebook (MS Office 2016) will be provided.
Please bring your lecture as PowerPoint or PDF-File on a USB stick.
In case that you need internet /special software for your presentation or if you have videos included into your file, please notify us in advance.
As lecture times vary, we please you to check your lecture times in advance.
Strict timekeeping will be essential for the smooth running of the conference.
We suggest to use a minimum font of 24 pt for your presentation slides.
A brief CV questionary enables the appropriate chair person to introduce all lecturers to the audience. Therefore lecturers are asked to download the CV form and saved with the Presenter’s lastname and return it until 30 April 2022 to .
Keynote lectures are planned for a duration of 35 minutes plus 5 minutes for discussion.
Other lectures are planned for a duration of 15 minutes plus 5 minutes for discussion.
Poster short presentations are planned for a duration of 5 minutes.
As a major guideline it is proposed to make the poster intelligible in itself, even in the absence of the author. It is suggested to divide the contents of each poster into introduction, results and conclusions, with a summary listing the pertinent results and conclusions.
The poster should be legible from a distance of 2-3 meters.
Standard size for posters is 0.85 x 1.2 m (DIN A0-German Standard) vertically oriented.
Therefore, please find the following specifications:
the minimum size should be 20 cm for graphs;
3 cm for the paper’s title and the names/adresses of the authors in the heading lable;
1,5 cm for sections headings such as introduction, results, labelling of figures and tables;
0,8 cm characters in height for further text;
Line spacing: 1,1 cm at minimum; 10 of such lines correspond to one figure;
Please use colours, symbols and schemes for improved clarity.
The posters will be shown during the whole conference.
Please hang up your poster at the beginning of the conference.
Directions to DECHEMA: Please find a detailed description at www.dechema.de/location.
DECHEMA is located in a so called "Umweltzone" in the city of Frankfurt. If you intend to reach us by car, you need the corresponding green sticker on your car. More information available at www.umweltzone.frankfurt.de.
Parking capacities at DECHEMA are very limited. Please use public parking lots along Theodor-Heuss-Allee: Congress-Center-Messe (CMF) or at the fair tower (Messeturm).
Going to DECHEMA by train? Use the joint offer from Deutsche Bahn (DB) and DECHEMA and travel to our events with reduced fares.
We recommend you the following hotels. We have not reserved any contingent of rooms.
Please book a room by yourself. When using the booking code you will get a special rate.
Maritim Hotel Frankfurt (5 min walking distance)
Theodor-Heuss-Allee 3
60486 Frankfurt am Main
Phone: 0049 69 75 78-1134
E-Mail:
Single room: around 100 EUR per night and incl. breakfast and wifi.
Please us the booking code "DECH52" for the reservation at the Maritim Hotel.
Mercure Hotel (10 min walking distance)
Voltastr. 29
60486 Frankfurt am Main
Phone: 0049 69 7926 0
E-Mail:
Booking code: DECHEMA
Single room: 107 EUR per night, incl. breakfast and wifi
Double room: 123 EUR per night, incl. breakfast and wifi
HOTEL FRANKFURT MESSE managed by Meliá Hotels International (15min walking distance)
Katharinenkreisel
60486 Frankfurt am Main
Phone: 0049 69 70730500
E-Mail:
Booking code: DECHEMA or 1277408
Single room: 92 EUR per night, incl. breakfast and wifi
DORMERO Hotel Frankfurt Messe
Lissabonner Straße 2
60327 Frankfurt am Main
Phone: 0049 30-202 13 300
E-Mail:
Booking code: CDECH
Single room: 99 EUR per night, incl. breakfast, minibar, Sky TV and wifi
Double room: 111 EUR per night, incl. breakfast, minibar, Sky TV and wifi
MOTEL ONE Frankfurt Messe
Europa-Allee 25
60327 Frankfurt
Phone: 0049 69 6612453-0
E-Mail:
Booking code: DECHEMA
Single room: 92,50 EUR per night, incl. breakfast and wifi
Double room: 107,50 EUR per night, incl. breakfast and wifi
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Gene Therapy Net is the information resource for basic and clinical research in gene therapy, and the site serves as a network in the exchange of gene therapy information and breaking news items. Visitors can keep track of the latest scientific papers, conference announcements, gene therapy jobs, regulations and guidelines. |
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We are pleased to welcome you again at DECHEMA House. We would like to offer you a carefree and safe stay in our house. To this end, we have developed a hygiene concept that incorporates the current recommendations and directives of the State of Hessen.
(as of April 2022, subject to change)
The most important points of the hygiene concept in brief:
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“3G ”-rule applies |
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Please keep at least 1.5 metres away from other people |
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Please wear a mouth and nose cover
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Please observe the etiquette for sneezing and coughing |
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Please wash an disinfect your hands regularly and thoroughly |
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No entrance with symptoms of sickness such as a temperature or a cough
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Please no handshakes! Give a smile instead
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You can download the detailed hygiene concept as PDF.
The nearest test center (without appointment) is the Testmobile at the Marriott Hotel (600 meters walk opposite MARITIM Hotel) https://www.testmobil-hessen.com/
You can search for further test centers in Frankfurt via the following link: https://www.corona-test-hessen.de
The acceptance of the hygiene concept is a prerequisite for entering the DECHEMA building. It will be brought to the attention of all visitors with the invitation or on site. We cannot agree to exceptions on site for reasons of infection control.
Your contact at DECHEMA will be happy to answer any further questions you may have.
We thank you for your support and stay healthy!
Further information from the authorities
Citizens' hotline Land Hessen:
For current questions regarding the coronavirus, the state of Hesse has set up a citizens' hotline, Tel.: 0800/555-4666, Monday to Friday from 08:00 - 20:00.
Information from the authorities
Decisions of the state government on Corona
Information for risk groups COVID-19 (RKI)
Current information of the Federal Ministry of Health on the corona virus
The challenges and issues of manufacturing and analytics of gene and cell therapeutics are very different from all other therapeutics, including biopharmaceuticals. A key factor of success is the management of multiple challenges addressing safety, purity and potency of these advanced therapies.
Robust and reliable manufacturing processes are still far from routine. Efficient gene transfer vectors, delivering the therapeutic gene into the target cells without causing any associated pathogenic effect, need to be developed and produced in large-scale.
Depending on the complexity and individuality of this product class, cell therapy manufacturing processes may comprise consistent procedures of culture, expansion, genetic manipulation, stimulation, and in case of treatments of multiple patients, cell banking. Analytics and quality control need to be adapted to this broad range of complex manufacturing processes ensuring adequate safety, purity and potency of the final products.
The conference is an initiative of the DECHEMA working groups Cell Culture Technology and Medical Biotechnology.
Mehr Informationen: Programme Call for Last Minute Poster Registration and Fees Exhibition & Sponsoring Exhibitors & Sponsors Keynote 2022 Conference Topics Committee Information for Authors Venue and Accommodation Privacy Policy Terms & Conditions Media Partner Corona Information and Hygiene Concept
DECHEMA-Fokus-Themen:
#ATMP2022
