Tuesday, 17 May 2022

10:00	Registration
11:00	Welcome
	Session: Innovative iPSC- and MSC-derived therapeutics Chair: Roland Wagner, Technical University Braunschweig
11:05	Keynote lecture: "Scalable generation of custom-made immune cells for innovative cell-based immunotherapies and industrial applications" Nico Lachmann, MHH Medizinische Hochschule Hannover
11:45	"Process design considerations for hMSC-based products" Jan Barekzai; Florian Petry; Peter Czermak; Denise Salzig, Technische Hochschule Mittelhessen
12:05	Poster talk: "Biomimetic matrices enable highly defined isolation of functional mesenchymal stromal cells in xeno-/serum-free media" Kristina Thamm¹; Kristin Moebus²; Russel Towers²; Richard Wetzel¹; Manja Wobus²; Sandra Segeletz², ¹ denovoMATRIX GmbH; ² University Hospital Carl Gustav Carus der Technischen Universität Dresden
12:10	Short break
	Session: Therapeutic exosomes Chair: Denise Salzig, University of Applied Sciences Mittelhessen, Gießen
12:20	Keynote lecture: "Functional extracellular vesicles as new therapeutic modality – Exosomes’ Road to the clinic" Jens Gruber, Curexsys GmbH, Göttingen
13:00	Poster talk: "Challenges and Solutions for Production of Therapeutic Exosomes" Christoph Keysberg, Kerstin Otte, Biberach University of Applied Sciences
13:05	Lunch
	Session: New approaches in cell-based therapies Chair: Hansjörg Hauser, Helmholtz Centre for Infection Research, Braunschweig
14:00	Keynote lecture: "Engineering T cell receptors for adoptive cell therapy" Kilian Schober, Universitätsklinikum Erlangen
14:40	"Cell-mediated visualization of local infections and drug delivery " Dagmar Wirth¹; Mario Köster¹; Sandhya Kumar¹; Peter Behrens²; Hansjörg Hauser¹; Andreas Kirschning³, ¹ Helmholtz Zentrum für Infektionsforschung mbH; ² Institute for Anorganic Chemistry; Leibniz University Hannover; ³ Institute for Organic Chemistry, Leibnitz University Hannover
15:00	Keynote lecture: "Harnessing human 3D Cell Models to accelerate the development of advanced therapies" Catarina Brito, iBET & ITQB-NOVA, Oeiras/Portugal
15:40	Coffee break
	Session: Tumor vaccines - strategies for personalisation and production  Chair: Jessica Horbelt, Fraunhofer IPA, Stuttgart
16:15	Keynote lecture: "Application of mRNA technology in cancer therapy" Felicitas Müller, BioNTech SE, Mainz
16:55	"Improved production strategies for oncolytic Measles virus as therapeutic cancer treatment" Dustin Eckhardt; Denise Salzig; Peter Czermak, Technische Hochschule Mittelhessen
17:15	End of lecture programme of day 1
17:30 - 20:00	Get Together / Poster Session

 
Wednesday, 18 May 2022

	Session: Clinical ATMP application and manufacturing Chair: Andrea Traube, KyooBe Tech GmbH, Leinfelden-Echterdingen
09:00	Keynote lecture: "Home brewn CAR-T-Cell" Michael Schmitt, Uniklinik Heidelberg, Heidelberg
09:40	"Running title: Modular mini-factories for the automated and scalable production of ATMPs" Andreas Traube; Jessica Horbelt; Martin Thoma; Natalie Gebken; Sarah Kleine-Wechelmann; Milena Frahm; Markus Schandar; Michael Klinger; Sebastian Puls; Rolf Wössner; Michael Pfeifer; Tobias Sauer, Fraunhofer IPA
10:00	"Real laboratory for automated and digitalized ATMP production" Georg Popp¹; Rolf van Lengen²; Andreas Traube³; Karsten Seidl⁴; Carsten Claussen⁵; Michael Baßler⁶; Paul Franz¹; Anna Dünkel¹; Ulrike Köhl¹; Stephan Fricke¹, ¹ Fraunhofer IZI; ² Fraunhofer IESE; ³ Fraunhofer IPA; ⁴ Fraunhofer IMS; ⁵ Fraunhofer ITMP; ⁶ Fraunhofer IMM
10:20	Coffee break
	Session: Innovative production strategies Chair: Anna Katharina Heide, RUHR-IP Patentanwälte, Essen
11:00	Keynote lecture: "Single Cell Multi-Omics Driving the Future of Adoptive Cell Therapy" Andreas Schmidt, Singleron Biotechnologies GmbH, Köln/D
11:40	"AIDPATH – Modular Manufacturing Platform for AI-enabled hospital-based ATMP Production – A Concept Presentation" Frederik Erkens, Fraunhofer Institute for Production Technology IPT
12:00	Poster talk: "Fluidic imaging as PAT tool for cell aggregate monitoring" Martin Kraft, Bayer AG
12:05	Keynote lecture: "Tackling the Challenges of AAV Vector Manufacturing" Nicole Faust, CEVEC Pharmaceuticals GmbH, Köln
12:45	Lunch
	Session: From regulatory framework to clinical application Chair: Hansjörg Hauser, Helmholtz Centre for Infection Research, Braunschweig
13:30	"Risk Assessment – An intelligent tool for the evaluation of critical starting material" Claudia Papewalis¹; Marco Schmeer²; Martin Schleef², ¹ Valicare GmbH; ² PlasmidFactory GmbH
13:50	"Plausibility of EP Patents - Post-filed experimental data as support of sufficiency of disclosure and inventive step of the Invention?!" Anna Katharina Heide, RUHR-IP Patentanwälte, Essen
14:10	"The current regulatory framework of ATMP storage and distribution – consequences and challenges " Andrea Zobel, World Courier
14:30	Coffee & Networking
15:00	End of conference

 (as of 9 May 2022, subject to change)

 

 

The deadline for submitting presentations has passed. You can submit last minute posters on the following topics:

• Challenges in development of gene transfer vectors
• Non-viral methods for gene transfer
• Genome editing for cell-based therapies
• Somatic cell therapeutics
• iPSC- and MSC-derived therapeutics
• Allogeneic vs. autologous therapeutic products
• Strategies against solid tumors
• Advanced manufacturing processes and scalability
• Automation and digitalization in ATMP production
• Optimization and new methods in quality control
• Clinical studies and clinical applications
• Regulatory pathways and challenges

Last Minute Poster submission until 30 April 2022

Please prepare 1-2 pages (incl. figures, max. size 1 MB, max. 2 pages).
You can use the Template to correctly format your contribution and upload it as PDF file.
Enter the author list (author and co-author/s) and affiliations in the same order as in your abstract.

Accepted abstracts will be published for all conference participants in a book of abstracts (PDF).
The conference language is English.

Please note: Registration fee cannot be waived for authors.

For companies / institutions interested in exhibiting or sponsoring at the ATMP 2022 conference, we offer the following standard packages:

EXHIBITION:   1.500,00 € (excl. VAT)

• 6sqm booth area including 1 table, 2 chairs, 1 power supply, internet access
• Webpage announcement (logo and link on conference homepage)
• 1 complimentary full conference ticket

The exhibition area is located in the foyer of the lecture hall and close to the catering area.

 

SPONSORPACKAGE A:   2,500.00 EUR (excl. VAT)

• 1/1 page advert on the inside front cover or back cover (inside) of the book of abstracts
  (colour, size A5, first come - first served)
• One complimentary conference ticket for the scientific programme included
• Display of a company information flyer at the registration desk
• Logo projected at the speakers’ podium in the conference hall before and after lecture sessions and during poster session (slide show with assignment of all sponsors).
• Logo with company profile on the conference website (500 characters) with link to the company website

• Logo placed inside the programme/book of abstract
  
  

SPONSORING PACKAGE B:   1,000.00 EUR (excl. VAT)

• Display of a company information flyer at the registration desk
• Logo projected at the speakers’ podium in the conference hall before and after lecture sessions and during poster session (slide show with assignment of all sponsors).
• Logo with company profile on the conference website (500 characters) with link to the company website
• Logo placed inside the programme/book of abstract
  
  

SPONSORING PACKAGE C:    800,00 € (excl. VAT)

• Logo with company profile on the conference website (500 characters) with hyperlink to the company website
• Logo placed inside the programme/book of abstract
• Display of PowerPoint slide during breaks of the conference

Exhibitors

	ASEPTIC TECHNOLOGIES manufactures innovative aseptic production equipment, designed to provide safer & easier aseptic filling operations. The AT-Closed Vial® is provided ready to fill with its stopper secured in place, and sterilized by gamma irradiation.  The filling is performed by a special needle piercing the stopper, which is then immediately heat-resealed by laser and capped. The drug product is thus never in contact with the environment. The AT-Closed Vial® ensures uncompromised Container Closure Integrity at -80°C and in vpLN2. Further information at: www.aseptic.com
	Barkey is a German family business for medical technology in the field of warming devices.  The main goals: Preventing hypothermia and advancing Cell & Gene therapy research. For this purpose, Barkey produces dry temperature solutions for heating or thawing blood products, cell materials, infusion solutions, etc. The headquarters in Leopoldshöhe, Germany, the two locations in Boston, US and Shanghai, CN as well as a large distributor network enable the worldwide availability of the products. Further information at: www.barkey.de
	Focusing on people and innovations, OLS OMNI Life Science accelerates research in life sciences and biotechnology with smart, reliable, and user-friendly technologies. Our products are found in laboratories of both the public and private sector, as well as laboratories of the pharmaceutical and biotechnology industries. The broad portfolio includes instruments for cell counting, cell culture, imaging, flow cytometry, and real rime cell analysis as well as media, reagents, consumables, services and consultation. This enables us to accompany you during the entire research process, from conception to conclusion. Further information at www.ols-bio.de
	PELOBIOTECH GmbH is a European supplier of reagents for biomedical research with a focus on primary cell culture. Choose from a portfolio of more than 20,000 products including primary cells, media and cell culture tools. For Extracellular Vesicle research and production we offer defined media optimized for mesenchymal stem cell culture and free of EVs, and some tools (defined coatings, cryo-preservation media & 3D Co-Culture Tools) optimized for Mesenchymal Stem/Stromal Cell research in this field. These reagents are available in R&D, GMP-like and GMP quality. Talk to us at the booth. Further information at: www.pelobiotech.com
	PeproTech creates the building blocks of your life science research by manufacturing high-quality products that advance scientific discovery and human health.  Since 1988, we have grown into a global enterprise with state-of-the-art manufacturing facilities in the US, and offices around the world. With over 2,000 products, PeproTech has developed and refined innovative protocols to ensure quality, reliability and consistency. Our mission is to provide the highest quality products and premium support that address the needs and demands of today's scientists and researchers.  We pride ourselves on being a trusted partner within the scientific community. Comprehensive line of Cytokines and Antibodies GMP Cytokines for Cell, Gene and Tissue Therapy Animal-Free Cytokines ELISA Development Kits Cell Culture Media Kits / Supplements Further information at www.peprotech.de
	www.stemcell.com

Sponsors

	denovoMATRIX designs and produces biomaterials, which address cell manufacturing challenges, enabling rapid growth rates of viable cells and meeting safety/ethical requirements of the industry. We are achieving this by employing our modular, biomimetic technology to functionalize cell culture ware as well as scaffolds as microcarriers. Our customers can apply our validated, ready-to-use products for isolation and expansion of MSC or expansion of iPSC in animal-component-free processes. We are further offering development service to create custom solutions with our clients. Further information at: www.denovomatrix.com
	RUHR IP Patent Attorneys located in Germany since 2006 represent their clients internationally and give advice with strategic vision, precisely focused on the client´s needs: with our excellently trained and experienced patent attorneys and our international and professionally diversified team. The needs of clients in the IP advisory environment have changed towards more comprehensive strategic and commercial advice. In particular, the support of SME, but also special cases, function more purposefully and efficiently with a flexible, medium-sized, integrated patent law firm. To this end, RUHR-IP offers agile and fast processes, professional expertise and a well-connected network in neighbouring areas of expertise. Further information at www.ruhr-ip.com
	Valicare, a daughter company of Syntegon Technology, is a GMP compliance service supplier, headquartered in Frankfurt am Main since 2002. Experienced senior GMP consultants, engineers and natural scientists support worldwide the pharma, biotech and medical device industry with GMP consulting, risk-based qualification and with validation of processes, systems and methods. Special competencies and services are offered for sterile filling (process development and validation of isolators) and for advanced therapy medicinal products (ATMP). Further information at www.valicare.com

The conference will highlight the challenging field of gene and cell therapeutic approaches, especially focusing on the following topics:

• Challenges in development of gene transfer vectors
• Non-viral methods for gene transfer
• Genome editing for cell-based therapies
• Somatic cell therapeutics
• iPSC- and MSC-derived therapeutics
• Allogeneic vs. autologous therapeutic products
• Strategies against solid tumors
• Advanced manufacturing processes and scalability
• Automation and digitalization in ATMP production
• Optimization and new methods in quality control
• Clinical studies and clinical applications
• Regulatory pathways and challenges

Ulf Bethke                           
Miltenyi Biotec GmbH, Bergisch Gladbach               

Hansjörg Hauser                 
Helmholtz Centre for Infection Research, Braunschweig

Anna Katharina Heide       
RUHR-IP, Essen

Jessica Horbelt                    
Fraunhofer IPA, Stuttgart

Cornelia Kasper                  
University of Natural Resources and Life Sciences, Vienna

Konrad Kohler                    
BioMedTech, Forschungscampus Reutlingen

Thomas Noll                        
University of Bielefeld

Ralf Pörtner                        
Technical University Hamburg

Denise Salzig                       
University of Applied Sciences Mittelhessen, Gießen

Bernd Schröder                   
Miltenyi Biotec GmbH, Teterow

Karin Tiemann                    
DECHEMA e.V., Frankfurt am Main

Andrea Traube                    
KyooBe Tech GmbH, Leinfelden-Echterdingen

Roland Wagner                   
Technical University Braunschweig

Registration

Dear lecture and poster authors, please note: Registration fee cannot be waived for authors.
Please use the online registration.
If you are unable to present your lecture for any reason, please let us know as soon as possible.

Conference Language

The official language of the conference is English. Simultaneous translation will be not available.

Technical Information

A video projector and a notebook (MS Office 2016) will be provided.
Please bring your lecture as PowerPoint or PDF-File on a USB stick.
In case that you need internet /special software for your presentation or if you have videos included into your file, please notify us in advance.

Keynote Lectures / Lectures / Poster Presentations

As lecture times vary, we please you to check your lecture times in advance.
Strict timekeeping will be essential for the smooth running of the conference.
We suggest to use a minimum font of 24 pt for your presentation slides.

A brief CV questionary enables the appropriate chair person to introduce all lecturers to the audience. Therefore lecturers are asked to download the CV form and saved with the Presenter’s lastname and return it until 30 April 2022 to .

Keynote lectures are planned for a duration of 35 minutes plus 5 minutes for discussion.
Other lectures are planned for a duration of 15 minutes plus 5 minutes for discussion.
Poster short presentations are planned for a duration of 5 minutes.

Preparation of Poster

As a major guideline it is proposed to make the poster intelligible in itself, even in the absence of the author. It is suggested to divide the contents of each poster into introduction, results and conclusions, with a summary listing the pertinent results and conclusions.

The poster should be legible from a distance of 2-3 meters.
Standard size for posters is 0.85 x 1.2 m (DIN A0-German Standard) vertically oriented.
Therefore, please find the following specifications:

• the minimum size should be 20 cm for graphs;

• 3 cm for the paper’s title and the names/adresses of the authors in the heading lable;

• 1,5 cm for sections headings such as introduction, results, labelling of figures and tables;

• 0,8 cm characters in height for further text;

• Line spacing: 1,1 cm at minimum; 10 of such lines correspond to one figure;

• Please use colours, symbols and schemes for improved clarity.

The posters will be shown during the whole conference.
Please hang up your poster at the beginning of the conference.

Venue

DECHEMA e.V.
Theodor-Heuss-Allee 25
60486 Frankfurt/Main
Germany

 

Directions to DECHEMA: Please find a detailed description at www.dechema.de/location.

DECHEMA is located in a so called "Umweltzone" in the city of Frankfurt. If you intend to reach us by car, you need the corresponding green sticker on your car. More information available at www.umweltzone.frankfurt.de.

Parking capacities at DECHEMA are very limited. Please use public parking lots along Theodor-Heuss-Allee: Congress-Center-Messe (CMF) or at the fair tower (Messeturm).

Going to DECHEMA by train? Use the joint offer from Deutsche Bahn (DB) and DECHEMA and travel to our events with reduced fares.

 

Accomodation

We recommend you the following hotels. We have not reserved any contingent of rooms.
Please book a room by yourself. When using the booking code you will get a special rate.

Maritim Hotel Frankfurt (5 min walking distance)
Theodor-Heuss-Allee 3
60486 Frankfurt am Main
Phone: 0049 69 75 78-1134
E-Mail: 

Single room: around  100 EUR per night and incl. breakfast and wifi.
Please us the booking code "DECH52" for the reservation at the Maritim Hotel.

Mercure Hotel (10 min walking distance)
Voltastr. 29
60486 Frankfurt am Main
Phone: 0049 69 7926 0
E-Mail: 

Booking code: DECHEMA
Single room: 107 EUR per night, incl. breakfast and wifi
Double room: 123 EUR per night, incl. breakfast and wifi

 

HOTEL FRANKFURT MESSE managed by Meliá Hotels International  (15min walking distance)
Katharinenkreisel
60486 Frankfurt am Main
Phone: 0049 69 70730500
E-Mail:

Booking code: DECHEMA or 1277408
Single room: 92 EUR per night, incl. breakfast and wifi
 

DORMERO Hotel Frankfurt Messe
Lissabonner Straße 2
60327 Frankfurt am Main
Phone: 0049 30-202 13 300
E-Mail:

Booking code: CDECH
Single room:   99 EUR per night, incl. breakfast, minibar, Sky TV and wifi
Double room:   111 EUR per night, incl. breakfast, minibar, Sky TV and wifi

MOTEL ONE Frankfurt Messe
Europa-Allee 25
60327 Frankfurt

Phone: 0049 69 6612453-0
E-Mail:  

Booking code: DECHEMA
Single room:  92,50 EUR per night, incl. breakfast and wifi
Double room:  107,50 EUR per night, incl. breakfast and wifi

 

With our best thanks

	Gene Therapy Net is the information resource for basic and clinical research in gene therapy, and the site serves as a network in the exchange of gene therapy information and breaking news items. Visitors can keep track of the latest scientific papers, conference announcements, gene therapy jobs, regulations and guidelines.

We are pleased to welcome you again at DECHEMA House. We would like to offer you a carefree and safe stay in our house. To this end, we have developed a hygiene concept that incorporates the current recommendations and directives of the State of Hessen.
(as of April 2022, subject to change)

The most important points of the hygiene concept in brief:

	“3G ”-rule applies (only vaccinated, tested or recovered persons are admitted)
	Please keep at least 1.5 metres away from other people
	Please wear a mouth and nose cover
	Please observe the etiquette for sneezing and coughing
	Please wash an disinfect your hands regularly and thoroughly
	No entrance with symptoms of sickness such as a temperature or a cough
	Please no handshakes! Give a smile instead

You can download the detailed hygiene concept as PDF.

The nearest test center (without appointment) is the Testmobile at the Marriott Hotel (600 meters walk opposite MARITIM Hotel) https://www.testmobil-hessen.com/

You can search for further test centers in Frankfurt via the following link: https://www.corona-test-hessen.de

The acceptance of the hygiene concept is a prerequisite for entering the DECHEMA building. It will be brought to the attention of all visitors with the invitation or on site. We cannot agree to exceptions on site for reasons of infection control.

Your contact at DECHEMA will be happy to answer any further questions you may have.

We thank you for your support and stay healthy!

 

Further information from the authorities

Citizens' hotline Land Hessen:
For current questions regarding the coronavirus, the state of Hesse has set up a citizens' hotline, Tel.: 0800/555-4666, Monday to Friday from 08:00 - 20:00.

 

Information from the authorities

Decisions of the state government on Corona

Information for risk groups COVID-19 (RKI)

Current information of the Federal Ministry of Health on the corona virus