The ultimate goal of metabolic and biochemical engineering is to create novel products and bioprocesses for commercialization. Whereas scientific and technical aspects are typical matters of training programs in universities, the sensitive steps of launching a product and process, which includes transferring technology from labs to production sites, are rarely addressed. This workshop will deal with the real process development and implementation of the key cephalosporin antibiotic intermediate 7-ACA from scratch up to a level > 1000 tons per year. Cephalosporin C is produced by fermentation, purified by large scale chromatography and the side-chain removed by enzymatic cleavage. The workshop will address the entire value-chain from fermentation, downstream-processing, enzyme development, purification and immobilization as well final cleavage conditions, product purification and isolation as well as environmental issues and the development of a sustainable bioprocess. Students will learn what the key questions are and how actions should be structured to make the novel product / process a success.
Prof. Dr. Andreas Liese, Hamburg University of Technology (TUHH)
Dr. Burkhard König, König & Funke Biotech GmbH
Sunday, 14 May 2023, 2:00 - 5:00 p.m.
Seminarhaus im congress centrum weimarhalle
70 EUR including snacks and drinks
Important note: booking is only possible in combination with a registration for the conference