Tuesday, 12 May 2020 (incl. Poster Speed Lectures, Part 1)
Wednesday, 13 May 2020 (incl. Poster Speed Lectures, Part 2)
| 11:00 |
Registration |
|---|---|
| 12:00 |
Business Lunch |
| 12:55 |
Welcome Address |
Biofabrication of 3D Models |
|
| Chair: |
M. Rimann, Zurich University of Applied Sciences, ICBT, Wädenswil/CH |
| 13:00 |
Keynote Lecture 1 Biofabrication of 3D tissues for disease modeling and drug discovery |
| 13:45 | Bio-printable 3D in vitro Tumor-Tissue-Modell for high throughput testing of tumortherapeutica M. Mueller¹; S. Hensler¹; C. Kühlbach¹; R. Glunz¹ ¹ Furtwangen University, Villingen-Schwenningen/D |
| 14:05 | Drop-on-demand bioprinting solutions for the fabrication of 3D cell culture systems aiming for in vitro screening applications K. Tröndle¹; A. Itani¹; F. Koch¹; R. Zengerle²; S. Zimmermann¹; P. Koltay¹ ¹ University of Freiburg/D; ² Hahn Schickard, Freiburg/D |
| 14:25 |
3D-printed mini-bone-organs with living osteocyte networks |
| 14:45 |
A microengineered platform for single cell tracking in 3D stem cell-based morphogenesis models |
| 15:05 | Coffee Break / Posters / Exhibition |
Synthetic Biology for Future Treatment Strategie |
|
| Chair: | R. Pörtner, TU Hamburg/D |
| 15:45 |
Keynote Lecture 2 Synthetic biology-inspired cell-based treatment strategies of the future |
| 16:30 |
Introduction Poster Speed Lectures and Poster Awards |
Poster Speed Lectures - Part 1 |
|
| Chair: |
R. Pörtner, TU Hamburg, Hamburg/D |
| 16:35 |
P3.3.06 Smarter surfaces to create cellular niches without artefactsT. Mentzel¹; A. Thomas¹; P. Lak¹; V. Schwartz¹; J. Sloan²; B. Birk²; P. Hahn²; P. Stengel²; N. Kaiser²; C. Oberfrank² ¹ Chemovator GmbH, Mannheim/D; ² BASF SE, Ludwigshafen/D |
| 16:39 |
P1.4.02 A versatile microfluidic tilting platform for investigating crosstalk between 3D microtissues and free-flowing cells |
| 16:43 |
P3.4.01 Optical clearing of 3D-cell cultures for substance screening |
| 16:47 |
P1.1.07 HA-based delivery system enhances drug transport to tumor spheroidsJ. Starigazdova¹; D. Zelencova²; K. Nesporova¹; D. Smejkalova¹; G. Huerta-Angeles¹; V. Velebny¹ ¹ Contipro, Dolní Dobrouc/CZ; ² The University of Veterinary Medicine and Pharmacy in Kosice/CZ |
| 16:51 |
P3.5.03 Impact of A Disintegrin And Metalloprotease 17 (ADAM17) inhibition combined with paclitaxel treatment in ovarian cancer spheroids |
| 16:55 |
P1.3.08 Potential and limitations of hybrid supramolecular-polysaccharide hybrid hydrogels for macrophage 3D cell culture modelsD. Hebel¹; M. Müller¹ ¹ University Siegen/D |
| 16:59 |
P1.2.03 Applying a microphysiological 3D human liver – islet microtissue platform to study metabolic diseases |
| 17:03 |
P1.1.10 Matrix-free culture of intestinal organoids in thermoformed microwells |
| 17:07 |
P1.3.02 Manufacturing of functional beta cell-mesenchymal stem cell-spheroids for transplantation or drug testing |
| 17:11 |
P3.3.02 Modular plug&play construction kit for the development of micro-physiological systems |
| 17:15 |
P3.6.02 Hydrogels formed from methylsulfone-bearing polymers provide convenient crosslinking kinetics for 3D cell culture and bioprintingS. Pearson¹; A. de Miguel Jiménez¹; R. Valbuena Mendoza¹; J. Paez¹; A. del Campo¹ ¹ INM-Leibniz Institute for New Materials, Saarbrücken/D |
| 17:19 |
P1.5.01 Autologous endothelial colony forming cells as promising cell source for endothelialization of TEVGsX. Kraus¹; M. Pflaum²; S. Thoms¹; R. Jonczyk¹; C. Blume¹; T. Scheper¹ ¹ Leibniz University Hanover/D; ² Medical University Hannover/D |
| 17:23 | End of Lecture Programme of Day 1 |
| 17:30 | Poster Session 1 / Poster Party (17:30-20:00) |
| 18:00 |
Section Member Assembly (18:00 – 19:00) DECHEMA Working Groups Cell Culture Technology and Medical Biotechnology |
Models for Host-Microbe Interactions |
|
| Chair: | H. Hauser, Helmholtz-Zentrum für Infektionsforschung (HZI), Braunschweig/D |
| 09:00 |
Keynote Lecture 3 Organoids: transformative tools to dissect innate immune responses to host-microbe interactionsN.C. Zachos¹ ¹ Johns Hopkins University School of Medicine, Baltimore, MD/USA |
| 09:45 | Microstructured 3D in vitro model of the small intestine epithelium for studying host-bacteria interactions M. García-Díaz¹; M. Cendra¹; R. Alonso-Román¹; E. Torrents¹; E. Martínez¹ ¹ Institute for Bioengineering of Catalonia (IBEC), Barcelona/E |
| 10:05 |
Microfluidic gut-liver axis - a platform for studies on host-microbiota interaction |
| 10:25 | Coffee Break / Posters / Exhibition |
From Blood-Brain Barrier to Heart Design |
|
| Chair: | I. Prade, FILK gGmbH, Freiberg/D |
| 11:00 | 3D blood brain barrier organoids as in vitro model for the biomedical application of ultrasmall gold nanoparticles V. Sokolova¹; S. van der Meer¹; T. Ruks¹; M. Epple¹ ¹ University of Duisburg-Essen, Essen/D |
| 11:20 | Force measurement apparatus for 3D bioprinted muscle tissues in multi well plate for drug development M. Rimann¹; M. Nosswitz¹ ¹ Zurich University of Applied Sciences, Wädenswil/CH |
| 11:40 |
Tissue brick macro-scale organ engineering for trabecular heart design |
| 12:00 |
Short Break |
Poster Speed Lectures - Part 2 |
|
| Chair: | I. Prade, FILK gGmbH, Freiberg/D |
| 12:05 |
P1.3.06 Investigation of tumor cell extravasation in a novel microfluidic device |
| 12:09 |
P1.3.09 Cancer associated fibroblasts shape the phenotype of macrophages in organotypic 3D colon cancer models |
| 12:13 |
P1.5.02 Isolation of patient-derived peritoneal colorectal cancer metastases and 3D cultivation in different matricesM. Sachet¹; H. Birnleitner¹; J. Stift¹; T. Bachleitner-Hofmann¹; M. Bergmann¹; H. Dolznig¹; R. Oehler¹ ¹ Medical University of Vienna/A |
| 12:17 |
P1.1.02 Targeting the fibrotic tumor microenvironment: Novel 3D co-culture organoids for pancreatic adenocarcinoma (PDAC) drug discoveryJ. Hänsel¹; B. Xie²; A. Ni Putu³; P. Proksch³; R. Mrsny²; N. Teusch¹; H. Yu³ ¹ Universität Osnabrück/D; ² University of Bath/UK; ³ Heinrich-Heine-University Düsseldorf/D |
| 12:21 |
P1.2.02 Development of vascularized melanoma skin equivalents for studying metastasis and anti-melanoma therapies |
| 12:25 |
P1.3.03 Evaluation of different long-term culture approaches for primary human hepatocytes and an optimized transfection method |
| 12:29 |
P1.1.03 Mesenchymal stem cell growth and differentiation in 3D systems under the influence of human platelet lysate |
| 12:33 |
P3.6.01 Mechanical properties of 3D printed scaffolds for heart valve tissue engineering |
| 12:37 |
P1.1.08 Novel biomimetic membranes for nanoparticle transport studies at biological barriers |
| 12:41 |
Lunch |
| 13:30 |
Poster Session 2 and Poster Prize Voting |
Liver Models and Toxicity Testing |
|
| Chair: | J. Kelm, PreComb Therapeutics AG, Wädenswil/CH |
| 14:30 |
Keynote Lecture 4 Do results from in vitro toxicity models translate to the human situation in vivo? |
| 15:15 |
Keynote Lecture 5 Prediction of human drug-induced liver injury (DILI) in relation to oral doses and blood concentrations |
| 16:00 |
HepaChipMWP – a microfluidic, perfusable and scalable in vitro model of the liver in multiwellplate format |
| 16:20 |
Coffee Break / Posters / Exhibition |
Advanced Assays and Devices |
|
| Chair: | T. May, InSCREENeX GmbH, Braunschweig/D |
| 16:50 |
Live cell imaging of perfused human taste cell-derived spheroids |
| 17:10 |
CellPulse: single pulse laser poration of cells |
| 17:30 |
Advanced in vitro management of three-dimensional cell cultures and explanted tissue |
| 17:50 | Avoiding common pitfalls of 3D culture model assay development with appropriate validation and controls T. Riss¹ ¹ Promega Corporation, Madison, WI/USA |
| 18:10 |
End of Lecture Programme of Day 2 |
| 19:30 |
Scientific Award Ceremony / Conference Dinner Schlossberg Restaurant Dattler |
3D Models for Molecular Mechanisms |
|
| Chair: | H. Ruffner, Novartis Institutes for BioMedical Research, Basel/CH |
| 09:00 |
Keynote Lecture 6 Organotypic 3D models to characterize the molecular requirements of immune cell infiltration and activation |
| 09:45 |
Molecular control of ErbB2/Her2-driven 3D breast tumor growth: mechanistic and therapeutic implications |
| 10:05 |
Development of a 4D-in vitro-test system for specificity and po-tency of 3rd generation chimeric antigen receptor-T-cells (CAR-T-cells) based on microcavity array-bioreactors |
| 10:25 | A patient-based 3D breast cancer cell model to tackle ER signalling A. Cartaxo¹; M. Estrada¹; G. Domenici¹; R. Roque²; F. Silva²; E. Gualda³; P. Loza-Alvarez³; S. André²; C. Brito¹ ¹ iBET, Instituto de Biologia Experimental e Tecnológica & Instituto de Tecnologia Química e Biológica António Xavier, Oeiras/P; ² IPOLFG, Lisboa/P; ³ ICFO, Castelldefels, Barcelona/E |
| 10:45 | Coffee Break / Posters / Exhibition |
From 3D Models to the Clinic |
|
| Chair: |
U. Marx, TissUse GmbH, Berlin/D |
| 11:15 |
Keynote Lecture 7 Advancing regulatory science through innovation; in vitro microphysiological systems |
| 12:00 | Mimicking human cancer heterogeneity and diversity by building the largest biobank of matched in vitro (organoid) and in vivo (PDX) X. Xu¹; P. Wang²; J. Zhou²; H. Li³ ¹ Crown Bioscience, Inc., Beijing/PRC; ² Crown Bioscience, Inc., Taicang/PRC; ³ Crown Bioscience, Inc., San Diego, CA/USA |
| 12:20 | OncoChip – a novel microfluidic platform for compound efficacy testing on human 3D microtumors M. Pawlak¹; S. Yüz²; B. Gierke¹; J. Hofmann³; U. Härle²; S. Werner²; B. Hagmeyer²; Z. von Guttenberg³; M. Stelzle²; C. Schmees² ¹ NMI TT Pharmaservices, Reutlingen/D; ² NMI Natural and Medical Sciences Institute at the University of Tübingen, Reutlingen/D; ³ ibidi GmbH, Gräfelfing/D |
| 12:40 | A new approach to synergize hyperthermia and radiotherapy in cancer treatments using an in vitro 3D micro-tumour system A. Thomsen¹; C. Aldrian¹; P. Lund²; A. Grosu¹; M. Leu³; P. Vaupel¹ ¹ University of Freiburg, Medical Center/D; ² Ortenau-Klinikum, Offenburg/D; ³ abc biopply ag, Solothurn/CH |
| 13:00 |
Closing Remarks |
| 13:10 |
Lunch |
| 14:00 |
End of the Conference |
