| Tuesday, 06 Feb 2018 |
| 09:30 |
Registration, Opening of exhibition |
| 11:00 |
Opening
K. Rübberdt, Head of Biotechnology
DECHEMA e.V. / Germany |
| 11:05 |
Welcome address
C. Ott, Head of Technology & Innovation
Hessen Trade & Invest GmbH / Germany
|
| 11:15 |
Impulse
FIS approach to industrial biocatalysis
- FIS and FIS R&D brief general presentation
- Why biocatalysis in industry
- FIS research model for biocatalysis implementation
- Examples with different enzymes
R. Motterle, Head Biotechnology Development
F.I.S. - Fabbrica Italiana Sintetici S.p.A. / Italy |
| 11:45 |
How to make very good enzymes even better – improving cheese coagulants by enzyme engineering
- The challenge of developing superior enzymes for complex industrial applications
- Multiple parameter optimization of camel chymosin by DoE-based library design
- Combination of various enzyme engineering strategies
C. Jäckel, Senior Research Scientist in Enzyme Innovation
Chr. Hansen / Denmark |
|
12:15
|
Lunch and networking at the exhibition floor,
Interactive discussions @ "topic tables"
|
| 14:00 |
Impulse
Enzymatic Processes for Industrial Applications
The merit of the enzymes utilized in the reactions which enzymes do better than the chemical reactions will be introduced:
- Hydration and dehydrataion reactions (nitrile hydratase and aldoxime dehydratase)
- Regioselective reaction (acid phosphatase)
- Dynamic kinetic resolution (hydrolysis of nitrile)
- Deracemization of racemic amines (amine oxidase)
- Stereoselective lyase reaction (hydroxynitrile lyase)
Y. Asano, Head of Enzyme Chemistry Laboratory
Toyama Prefectural University, Biotechnology Research Center / Japan |
| 14:45 |
Enzymes in the Flavor and Fragrance Industry
- Diverse, exciting application areas for enzymes in F&F
- Different enzyme-based catalyst and reaction formats
- Plug-in solutions for multi-step synthetic schemes (hybrid routes)
- Engineering options help to address performance and cost issues
- Partnering offers unique opportunities
F. Brühlmann, Group leader Biotechnology Department
Firmenich / Switzerland |
| 15:15 |
Microbial transglutaminase enabling highly site-specific labeling of proteins
- Identification and characterization of a microbial transglutaminase
from the spore-forming bacterium Kutzneria albida
- From a promiscuous to a specific enzyme - How digitally controlled
high-density peptide arrays may predict the best substrates
- Versatile enzyme enabling bio-orthogonal production of active diagnostic and pharmaceutical ingredients on the industrial scale
W. Steffen, Project Leader Enzyme and Protein Technologies,
Roche Diagnostics / Germany |
|
15:45
|
Coffee break and networking at the exhibition floor,
Interactive discussions @ "topic tables"
|
| 17:00 |
In silico enzyme design: the need for speed
- The importance of speeding up enzyme discovery & development
- Why we use computer simulations to design industrial enzymes
- Case studies from Zymvol Biomodeling
M. F. Lucas, Co-founder & CEO
Zymvol Biomodelling / Spain |
| 17:30 |
Navigating Functional Enzyme Sequence Space: A Holistic Bioinformatics Perspective
- Enzyme archetypes: Clustering sequence space by functional hotspot positions
- Mutational hotspots: An accelerated molecular dynamics approach
- Enzyme Optimization: Combinatorial library design by virtual prototyping
S. Benson, Co-founder & CEO
Candidum / Germany |
| 18:00 |
Secure supply for commercial Enzymes – The Relevance of a reliable and experienced biotechnological manufacturer (CMO) for a plethora of markets
- White biotechnology is Corden BioChem’s business, your biotech hub in the heart of Europe
- Corden BioChem is an industrial manufacturing partner supplying into food, feed as well as pharma and fine chemical market
- Experienced team for industrialization and scale-up
- Compliance to work with different authorities
J. Ohl, Senior Business Development Manager
Corden BioChem / Germany |
18:30
|
Networking at the exhibition floor,
Interactive discussions @ "topic tables" |
| 19:00 |
Networking Dinner (click here for more information)
(Location: Bar Life-Style@Maritim Hotel, Theodor-Heuss-Allee 3, 60486 Frankfurt/M.) |
| 23:00 |
End of first PRAXISforum day |
| |
|
| Wednesday, 07 Feb 2018 |
| 09:00 |
Re-Opening exhibition |
| 09:30 |
A few studies about lipases
- Strategy to optimize new biocatalysts
- Enzyme toolbox
- Case studies
A. Robic, Scientific Manager
Protéus / France |
| 10:00 |
Best practices in the biocatalytic production of hydroxy-functionalised chemicals: From lab to pilot to production using hydratases and monooxygenases.
- Integration of biocatalysis into chemical production processes
- Strategies to produce hydroxy-functionalised molecules biocatalytically
- Enzyme and Reaction engineering to optimize biocatalytic processes
- Scale-up of hydratase and monooxygenase reaction
M. Schürmann, Principal Scientist Biocatalysis
InnoSyn / The Netherland
|
| 10:30 |
Südzucker activities with industrial enzymes
- General overview about the application of enzymes in the whole
Südzucker group (Inulin, Starch, Isomalt, Ethanol)
- Focus will be enzymes in ethanol production
- Details about the application of α-amylases, glucoamylases,
proteases, viscosity reducing enzymes, trehalases and phytases
M. Klingeberg, Senior Manager Microbiology
Südzucker / Germany
|
11:00
|
Coffe break and networking at the exhibition floor,
Interactive discussions @ "topic tables"
|
| 12:15 |
Biocatalysis: We create chemistry - with a little help from enzymes!
- Enzymes are incredibly powerful catalysts – opening new opportunities for the chemical industry
- First applications aimed at chiral intermediates for pharma
- The scope of enzyme catalysis can be extended to high volume petrochemicals
K. Baldenius, Head of Biocatalysis Research
BASF / Germany |
| 12:45 |
From Discovery to Product – Development of an Enzymatic Solution for Chronic Wound Treatment
- Identification and characterization of a fibrin degrading protease from the larvae of Lucilia sericata
- Development of a scalable microbial production process for the new enzyme Aurase
- Development of a formulation that enables application of the enzyme product after long storage under unfavourable conditions in order to effectively treat potentially millions of patients worldwide that suffer from painful chronic wounds.
A. Pelzer, Platform Coordinator Tailor-made Biocatalysts
BRAIN / Germany |
| 13:15 |
Viral contaminations: a common problem for microbial enzyme production
- Phages – overview
- Phages as contaminants in enzyme production and fermentation processes
- Detection methods
- Corrective actions
- Outlook
A. Dreusch, CEO
MicroMol / Germany
|
14:00
|
Lunch and networking at the exhibition floor,
Interactive discussions @ "topic tables"
|
| 15:15 |
End of PRAXISforum |
