Topic
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1.1 Advanced cell culture models
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P1.1.01
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Advanced physiologically relevant 3D models for pre-clinical screening D. Sabino¹; I. Fixe¹; A. Foucher¹; F. Carpentier¹; M. Rochet¹; I. Topin¹; E. Mennesson¹; N. Normand¹; ¹ tebu-bio, Le Perray en Yvelines/F
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P1.1.02
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Evaluation of EGFR induced on-target and target-mediated adverse effects in a microfluidic 3D human lung tumour – full thickness skin co-culture model J. Hübner¹; M. Raschke²; I. Rütschle¹; S. Schnurre²; S. Gräßle¹; I. Maschmeyer¹; U. Marx¹; T. Steger-Hartmann²; ¹ TissUse GmbH, Berlin/D; ² Bayer AG, Berlin/D
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P1.1.03
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A 3D High-Content Screening assay as model system for polycystic kidney disease H. Bange¹; T. Booij²; W. Leonhard³; K. Yan¹; D. Peters³; L. Price¹; ¹ OcellO B.V., Leiden/NL; ² LACDR, Leiden University, Leiden/NL; ³ Leiden University Medical Centre, Leiden/NL
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P1.1.04
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Parallelized Heart-on-a-chip with integrated Force Sensing incorporating human iPS-derived cardiac microtissues C. Probst¹; O. Schneider¹; S. Fuchs¹; P. Loskill¹; ¹ Fraunhofer IGB, Stuttgart/D
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P1.1.05
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Establishment of an advanced in vitro model to study nanomaterial-intestinal barrier interactions C. Hempt¹; C. Hirsch¹; M. Kucki¹; P. Wick¹; T. Buerki-Thurnherr¹; ¹ Empa - Swiss Federal Laboratories for Materials Science and Technology, St.Gallen/CH
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P1.1.06
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The Ocular DynaMiTES – A dynamic microfluidic in vitro system with improved predictability of ocular drug absorption N. Beißner¹; K. Mattern²; A. Dietzel²; S. Reichl¹; ¹ TU Braunschweig/ Institut für Pharmazeutische Technologie, Braunschweig/D; ² TU Braunschweig/ Institut für Mikrotechnik, Braunschweig/D
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P1.1.07
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Cell Processing in Microreactors: Real-time Monitoring of Cell Metabolism Using Sensor Particles and Surface Based, Gentle Cell Detachment K. Uhlig¹; C. Gehre²; S. Prill²; M. Stahl²; C. Duschl²; E. Schmälzlin³; L. Dähne⁴; T. Hellweg⁵; ¹ Fraunhofer-Institut für Zelltherapie und Immunologie IZI, Potsdam/D; ² Fraunhofer-Institute for Cell Therapy and Immunology, Potsdam/D; ³ Colibri Photonics GmbH, Potsdam/D; ⁴ Surflay Nanotec GmbH, Berlin/D; ⁵ Bielefeld University, Bielefeld/D
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P1.1.08
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Evaluation of a Novel Cell Culture Platform with Various Barrier Forming Cells for Dynamic Cultivation S. Hinkel¹; K. Mattern²; A. Dietzel²; S. Reichl¹; C. Müller-Goymann¹; ¹ TU Braunschweig/ Institut für Pharmazeutische Technologie, Braunschweig/D; ² TU Braunschweig/ Institut für Mikrotechnik, Braunschweig/D
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P1.1.09
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Ready-to-use 3D spheroid culture as a standard tool I. Prieto¹; ¹ StemTek Therapeutics, DERIO/E
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P1.1.10
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Dual targeting of prognostic biomarkers in the 3D microtumor model of advanced colorectal cancer C. Ilmberger¹; O. Hoffmann¹; J. Gülden²; T. Bühl²; J. Werner²; B. Mayer²; ¹ SpheroTec GmbH, Munich/D; ² Hospital of the LMU Munich, Munich/D
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P1.1.11
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Permeation Measurement for 3D Skin Culture in a Membrane Insert System H. Hsu¹; K. Schimek²; U. Marx³; R. Pörter⁴; ¹ Technische Universität Hamburg-Harburg, Hamburg/D; ² Department Medical Biotechnology of Biotechnology, Technische Universität Berlin, Berlin/D; ³ TissUse GmbH - TU Berlin, Berlin/D; ⁴ Institute of Bioprocess- and Biosystems Engineering, Hamburg University of Technology, Hamburg/D
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P1.1.12
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Preservation of tumor architecture and heterogeneity in long-term cultures of patient-derived explants S. Abreu¹; S. da Mata²; F. Silva³; M. Teixeira¹; T. Franchi Mendes¹; R. Fonseca⁴; B. Filipe²; S. Morgado²; I. Francisco²; M. Mesquita²; C. Albuquerque²; J. Serpa⁵; P. Chaves²; I. Rosa²; A. Felix⁵; E. R. Boghaert⁶; V. E. Santo¹; C. Brito¹; ¹ iBET/ITQB-NOVA, Oeiras/P; ² IPOLFG, Lisboa/P; ³ CEDOC-FCM-NOVA, Lisboa/P; ⁴ IPOLFG and FMUL, Lisboa/P; ⁵ IPOLFG and CEDOC-FCM-NOVA, Lisboa/P; ⁶ AbbVie, Chicago/USA
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P1.1.13 |
Establishment of a murine intestinal tissue model based on immortalized primary epithelial cells C. Fey¹; T. Truschel²; M. Schweinlin¹; H. Walles³; T. May²; M. Metzger³ ¹ Department of Tissue Engineering and Regenerative Medicine (TERM), University Hospital Würzburg, Würzburg/D; ² InSCREENeX GmbH, Braunschweig/D; ³ Translational Center Würzburg “Regenerative Therapies for Oncology and Musculoskeletal Diseases” (TZKME), Würzburg branch of the Fraunhofer Institute of Silicate Research (ISC), Würzburg/D |
P1.1.14 |
Development of a human epidermal burn wound model V. Schneider¹; ¹ Uniklinik Würzburg, Würzburg/D |
P1.1.15 |
Initial screening of novel copolymer micelles for biocompatibility and effects on cell motility Y. Yordanov¹; D. Aluani¹; B. Tzankov¹; V. Tzankova¹; R. Kalinova²; I. Dimitrov³; V. Bankova⁴; M. Popova⁴; B. Trusheva⁴; K. Yoncheva¹ ¹ Faculty of Pharmacy, Medical University of Sofia, Sofia/BG; ² Institute of Polymers, Bulgarian Academy of Sciences, Sliven/BG; ³ Institute of Polymers, Bulgarian Academy of Sciences, Sofia/BG; ⁴ Institute of Organic Chemistry with Center for Phytochemistry, Bulgarian Academy of Sciences, Sofia/BG |
P1.1.16 |
An injectable hybrid hydrogel for tissue engineering applications R. Wittig¹; B. Baumann²; M. Lindén² ¹ Institute for Laser Technologies in Medicine & Metrology (ILM) at Ulm University, Ulm/D; ² Institute for Inorganic Chemistry II, Ulm University, Ulm/D |
P1.1.17 |
A tissue engineered Full Thickness Skin Equivalent based on a non-contracting, biophysical optimised collagen type-I hydrogel P. Fey¹; C. Reuter²; T. Finger¹; M. Engstler²; H. Walles³; F. Groeber-Becker¹ ¹ Fraunhofer ISC - Translationszentrum für Regenerative Therapien TLZ-RT, Würzburg/D; ² Julius-Maximilians Universität Würzburg, Würzburg/D; ³ Universitätsklinikum Würzburg, Würzburg/D |
P1.1.18 |
Cell on cell – functionally immortalized smooth muscle cells as building blocks for 3D tissues A. Bleisch¹; ¹ InSCREENeX GmbH, Braunschweig/D |
P1.1.19 |
Evaluation of local inflammatory reactions following subcutaneous injection of a pro-inflammatory cocktail in a fully human ex vivo skin model C. Jardet¹; E. Pagès¹; E. Raude²; F. Seeliger³; L. Brandén³; E. Braun¹; M. Ingeslten³; P. Descargues⁴ ¹ GENOSKIN SAS, Toulouse/F; ² LAAS CNRS, Toulouse/F; ³ Drug Safety and Metabolism, iMED Biotech Unit, Astra Zeneca, Gothenburg/S; ⁴ Genoskin Inc., Boston (MA)/USA |
P1.1.20 |
A microchip array-based 3D culture system for the in vitro differentiation of osteoblasts W. Zhang¹; P. Tomakidi²; T. Steinberg²; R. Kohal³; E. Gottwald⁴; B. Altmann¹ ¹ G.E.R.N., Department of Oral and Maxillofacial Surgery, University Medical Center Freiburg, Freiburg im Breisgau/D; ² Department of Oral Biotechnology, University Medical Center Freiburg, Freiburg im Breisgau/D; ³ Department of Prosthetic Dentistry, University Medical Center Freiburg, Freiburg im Breisgau/D; ⁴ 300MICRONS GmbH, Karlsruhe/D |
P1.1.21 |
Automating 3D cell culture using a wood-derived hydrogel L. Paasonen¹; ¹ UPM-Kymmene Corporation, Helsini/FIN |
P1.1.22 |
Combining pluripotent stem cell-derived models of the blood-brain barrier with Multi-Organ-Chip systems L. Koenig¹; A. Ramme¹; D. Faust¹; E. Dehne¹; U. Marx¹; ¹ TissUse GmbH, Berlin/D |
P1.1.23 |
Microspheres-based scaffolds from poly(3-hydroxybutyrate) for 3D cell growth D. Chesnokova¹; I. Zharkova¹; A. Bonartsev¹; V. Voinova¹ ¹ Lomonosov Moscow State University, Faculty of Biology, Moscow/RUS |
P1.1.24 |
In vitro 3D bladder cancer model using PDX-derived cells R. Amaral¹; A. Ma²; H. Zhang²; K. Swiech¹; C. Pan² ¹ University of Sao Paulo, Ribeirao Preto/BR; ² University of California Davis, Sacramento/USA |
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Topic
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1.2 Innovative disease models
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P1.2.01
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A tissue engineering approach to model Primary Ciliary Dyskinesia N. Lodes¹; H. Walles²; S. Hackenberg³; H. Hebestreit⁴; M. Steinke²; ¹ University Hospital Würzburg, Chair of Tissue Engineering and Regenerative Medicine, Würzburg/D; ² University Hospital Würzburg, Chair of Tissue Engineering and Regenerative Medicine; Fraunhofer Institute for Silicate Research, Translational Center Regenerative Therapies, Würzburg/D; ³ University Hospital Würzburg, Department of Otorhinolaryngology, Plastic, Aesthetic and Reconstructive Head and Neck, Würzburg/D; ⁴ University Hospital Würzburg, Department of Paediatrics, Würzburg/D
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P1.2.02
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Characterisation of Bordetella pertussis virulence mechanisms using engineered human airway tissue models D. Kessie¹; ¹ Julius-Maximilians Universität Würzburg, Würzburg/D
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P1.2.03 |
Establishment and initial characterization of a simple 3D organotypic wound healing model S. Hensler¹; C. Kühlbach²; J. Parente³; S. Krueger-Ziolek⁴; K. Moeller⁴; M. Mueller² ¹ HS Furtwangen, Villingen-Schwenningen/D; ² Molecular Cell Biology Lab, Institute of Technical Medicine, HFU Furtwangen, Villingen-Schwenningen/D; ³ Institute of Technical Medicine, HFU Furtwangen University, Villingen-SChwenningen/D; ⁴ Institute of Technical Medicine, HFU Furtwangen University, Villingen-Schwenningen/D |
P1.2.04 |
Novel 3D tumour models with stromal components to evaluate the efficacy of immunotherapy with gene-engineered ROR1-specific CAR T cells J. Kühnemundt¹ ¹ University Hospital Würzburg, Department of Tissue Engineering & Regenerative Medicine, Würzburg, Germany;, Würzburg/D |
P1.2.05 |
Evaluation of pharmacological responses in InflammaSkin®, a fully human full-thickness ex vivo skin model reproducing key features of psoriatic lesions P. Lovato¹; C. Jardet²; E. PAGES²; A. David²; E. Braun²; H. Norsgaard¹; P. Descargues³ ¹ LEO Pharma, Ballerup/DK; ² GENOSKIN SAS, Toulouse/F; ³ Genoskin Inc., Boston (MA)/USA |
P1.2.06 |
Generation of human induced pluripotent stem cells (hiPSc)-derived hepatocyte organoids to study liver size control E. Saponara¹; ¹ Novartis Institutes of Biomedical Research, Basel/CH |
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Topic
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1.3 Complex and multi-cell type models
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P1.3.01
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Using the Real Architecture For 3D Tissue (3D RAFT™) System as a Versatile Tool to Build in vitro Epithelial Barrier Models T. Willstaedt¹; J. Langer¹; S. Schaepermeier²; S. Buesch²; T. D'Souza¹; L. Hussain¹; J. Schroeder²; ¹ Lonza Walkersville Inc., Walkersville, MD/USA; ² Lonza Cologne GmbH, Cologne/D
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P1.3.02
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Towards a three-dimensional microfluidic in vitro model to assess efficacy & safety of immune-stimulatory antibody drugs R. Nudischer¹; C. Bertinetti-Lapatki²; C. Claus³; K. Renggli⁴; C. Lohasz⁴; O. Frey⁵; A. Hierlemann⁴; A. Roth²; ¹ F. Hoffmann-La Roche Ltd., Basel/CH; ² Roche Pharma Research and Early Development, Roche Innovation Center Basel, Basel/CH; ³ Roche Pharma Research and Early Development, Roche Innovation Center Zürich, Schlieren/CH; ⁴ ETH Zürich, D-BSSE Basel, Basel/CH; ⁵ Insphero AG, Schlieren/CH
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P1.3.03
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MSCs Isolation in 3D cell culture conditions: challenges, modeling and perspectives. D. Egger¹; M. Kirsch²; T. Scheper²; A. Lavrentieva²; C. Kasper³; ¹ Department of Biotechnology, University of Natural Resources and Life Sciences, Vienna/A; ² Institute of Technical Chemistry, Leibniz University Hanover, Hannover/D; ³ Department of Biotechnology, University of Natural Resources and Life Sciences, Vienna/D
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P1.3.04
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Retina-on-a-Chip: Merging Organoid and Organ-on-a-Chip technology for complex multi-layer tissue models J. Chuchuy¹; K. Achberger²; C. Probst¹; J. Haderspeck³; J. Rogal¹; S. Liebau²; P. Loskill¹; ¹ Fraunhofer IGB, Stuttgart/D; ² Eberhard Karls Universität Tübingen, Tübingen/D; ³ Eberhard Karls Universität Tübingen, Stuttgart/D
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P1.3.05
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WAT-on-a-Chip: Microphysiological systems integrating white adipose tissue J. Rogal¹; C. Binder²; E. Rubiu²; C. Probst²; K. Schenke-Layland³; P. Loskill¹; ¹ Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB & Eberhard Karls University Tübingen, Stuttgart/D; ² Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB, Stuttgart/D; ³ Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB & Eberhard Karls University Tübingen, Tübingen/D
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P1.3.06
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High content screening of intestinal organoid cultures to visualize and quantify immune responses M. Madej¹; B. Herpers¹; L. Salinaro¹; K. Yan¹; L. Daszkiewicz¹; L. Price¹; ¹ OcellO B.V., Leiden/NL
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P1.3.07
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3D co-cultivation of beta cells and mesenchymal stromal/stem cells for diabetes therapy F. Petry¹; P. Czermak¹; D. Salzig¹; ¹ Institute of Bioprocess Engineering and Pharmaceutical Technology, University of Applied Sciences Mittelhessen, Gießen/D
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P1.3.08
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Modeling tumor microenvironment to address the dynamics of tumor, stromal and immune cell interactions S. Rebelo¹; C. Brito²; D. Simão³ ¹ iBET/ITQBAX-UNL, Oeiras/P; ² iBET, Instituto de Biologia Experimental e Tecnológica, Oeiras, Portugal; Instituto de Tecnologia Química e Biológica António Xavier, Universidede Nova de Lisboa, Oeiras, Portugal;, Oeiras/P; ³ iBET, Oeiras/P
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P1.3.09 |
Development of a 3D spheroid SK-MEL-28 tumor model and its characterisation J. Klicks¹; R. Rudolf¹; M. Hafner¹; ¹ Hochschule Mannheim, Mannheim/D |
P1.3.10 |
Trace Amines and Fatty Acids are Essential Endogenous Signaling Factors for β-Cell Activity and Insulin Secretion S. Hauke¹; C. Schultz²; ¹ European Molecular Biology Laboratory (EMBL), Heidelberg/D; ² Oregon Health and Science University (OHSU), Portland, OR/USA |
P1.3.11 |
In vitro vascularization of a human bone marrow model. K. Keskin¹; S. Sieber¹; U. Marx²; R. Lauster¹; M. Rosowski¹ ¹ Technische Universität Berlin, FG Medizinische Biotechnologie, Berlin/D; ² TissUse GmbH, Berlin/D |
P1.3.12 |
Development and characterization of PDX-derived 3D tumor microtissues as platform for screening targeted molecular therapeutics F. Chiovaro¹; N. Buschmann²; I. Agarkova²; A. Maier³; S. Messner²; J. Schueler³; P. Guye²; ¹ InSphero AG, Schlieren/CH; ² Insphero AG, Schlieren/CH; ³ Charles River, Freiburg im Breisgau/D |
P1.3.13 |
Imitation of the long-lived plasma cell survival niche of the human bone marrow in vitro Z. Uyar¹; S. Sieber¹; U. Marx²; R. Lauster¹; M. Rosowski¹ ¹ Technische Universität Berlin
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P1.3.14 |
Development of a Cardiac Organoid Culture System with hiPSC-derived Cardiomyocytes M. Schulze¹ ; B. Ulmer¹ ; M. Lemoine¹ ; A. Fischer¹ ; T. Eschenhagen¹; ¹ University Medical Center Hamburg-Eppendorf
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P1.3.17 |
Development of microvascular structures inside porous fibrin coated polydioxanon and PLLA/PLGA scaffolds S. Heene¹; S. Thoms¹; R. Jonczyk¹; T. Scheper¹; C. Blume¹ ¹ Leibniz Universität Hannover, Hannover/D |
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Topic
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1.4 Predictivity and validation
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P1.4.01
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Patient-derived 3D tumor cultures for clinical diagnostics and pre-clinical drug development. S. Basten¹; B. Herpers¹; K. Yan¹; T. Giesemann²; J. Schueler²; W. Vader³; L. Price⁴; ¹ OcellO B.V., Leiden/NL; ² Charles River, Freiburg/D; ³ Vitroscan B.V., Leiden/NL; ⁴ OcellO B.V., Leiden/D
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P1.4.02
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Detailed Cell-Material Interactions in 3D Cell Culture Systems R. Harjumäki¹; R. Nugroho²; J. Valle-Delgado²; Y. Lou¹; M. Yliperttula¹; M. Österberg²; ¹ University of Helsinki, Helsinki/FIN; ² Aalto University, Espoo/FIN
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P1.4.03
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Towards controlling the mobility of flowing cells in a hanging-drop network for microphysiological systems N. Rousset¹; M. de Geus¹; A. Kaestli¹; K. Renggli¹; A. Hierlemann¹; ¹ ETH Zürich, D-BSSE Basel, Basel/CH
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Topic
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2.1 Translation of models to solutions
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P2.1.01
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Three-dimensional in vitro co-culture model for nanoparticle-mediated transfection V. Sokolova¹; N. Bialas¹; L. Rojas¹; M. Epple¹; ¹ Inorganic Chemistry, University of Duisburg-Essen, Essen/D
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P2.1.02
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Microphysiological system based on human liver microtissues for intrinsic clearance prediction F. Hürlimann¹; S. Mannino²; C. Lohasz³; K. Renggli³; A. Hierlemann³; L. Suter-Dick²; O. Frey¹; ¹ InSphero AG, Schlieren/CH; ² University of Applied Sciences and Arts Northwestern Switzerland, Muttenz/CH; ³ ETH Zürich, D-BSSE, Basel/CH
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Topic
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2.2 Clinical applications
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P2.2.01
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Silencing GALNT1 or GALNT2 suppresses malignant phenotypes of pancreatic cancer cells T. Yeh¹; M. Huang²; ¹ National Taiwan University College of Medicine, 桃園市/RC; ² National Taiwan University College of Medicine, TAIPEI/RC
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P2.2.02
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Production of clinical grade temporary epidermal substitute obtained from hESC derived keratinocytes for the treatment of sickle cell leg ulcers: a challenge for regenerative medicine S. Domingues¹; Y. Masson¹; A. Poulet¹; M. Saidani¹; J. Polentes¹; G. Lemaitre¹; M. Peschanski¹; C. Baldeschi¹; ¹ ISTEM/CECS, Corbeil-Essonnes/F
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P2.2.03 |
Establishment of a Novel Functional in Vitro Assay to Investigate the Angiogenic Potential of Colonic Adenocarcinomas S. Bring Truelsen¹; G. Hagel¹; N. Mousavi²; H. Harling²; K. Qvortrup²; O. Thastrup¹; J. Thastrup¹ ¹ 2cureX A/S, Birkerød/DK; ² University of Copenhagen, Copenhagen/DK |
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TOPIC
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3.1 Innovative, advanced analytics
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P3.1.01 |
Imaging oxygen gradients in cell aggregates and in spheroids R. Meier¹; R. Meier¹; ¹ PreSens Precision Sensing GmbH, Regensburg/D |
P3.1.02 |
Application of video analysis for the evaluation of cardiac contractility in different in vitro model systems including freshly isolated adult rat cardiomyocytes and human iPSC-derived cardiomyocytes in 2D- and 3D-culture P. Beauchamp¹; S. Adrian²; S. Longnus²; T. Suter²; C. Zuppinger³ ¹ Bern University, Bern/CH; ² Bern University Hospital, Bern/CH; ³ University Hospital Bern, Bern/CH |
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Topic
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3.2 Specific assay development
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P3.2.01
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Microfluidics: a powerful tool to recreate in vivo environment C. Vergne¹; B. Rouffet²; S. Renard³; M. Verhulsel²; ¹ Fluigent, Villejuif/FP; ² Fluigent, Villejuif/F; ³ Fluigent GmbH, Jena/D
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P3.2.02
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An assay to characterize the impact of cigarette smoke exposure on mucociliary clearance in-vitro. S. Frentzel¹; L. Ortega Torres¹; S. Majeed¹; P. Leroy¹; F. Zanetti¹; M. van der Toorn¹; M. Peitsch¹; J. Hoeng¹; ¹ Philip Morris Products S.A., Neuchatel/CH
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P3.2.03
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Minimalistic hydrogel matrices to direct early neural progenitors from pluripotent stem cells in 3D culture A. Meinhardt¹; A. Ranga²; E. Tanaka³; M. Lutolf⁴; C. Werner⁵; ¹ Leibniz Institute of Polymer Research Dresden, Max Bergmann Center of Biomaterials Dresden, Dresden/D; ² KU Leuven, Leuven/B; ³ Research Institute of Molecular Pathology, Vienna/A; ⁴ Ecole Polytechnique Fédérale de Lausanne, Lausanne/CH; ⁵ Leibniz Institute of Polymer Research Dresden, Max Bergmann Center of Biomaterials Dresden, and Center for Regenerative Therapies Dresden, TU Dresden, Dresden/D
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P3.2.04
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Real-Time Assay for Apoptosis using Complementation of Annexin V Luciferase Subunits T. Riss¹; K. Kupcho¹; J. Shultz¹; J. Hartnett¹; R. Hurst¹; W. Zhou²; R. Akiyoshi³; A. Niles¹; ¹ Promega Corporation, Madison/USA; ² Promega Biosciences, San Louis Obispo/USA; ³ Olympus Corporation, Tokyo/J
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P3.2.05
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Benefits of Real-Time Measurements of Cell Health in 2D or 3D Using a Plate Reader T. Riss¹; ¹ Promega Corporation, Madison/USA
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P3.2.06
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Volume Regulation of HaCaT Spheroids in Response to Hypotonic Stimuli E. von Molitor¹; ¹ Hochschule Mannheim, Mannheim/D
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P3.2.07
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Calcium signals in taste-bud like 3D cultures T. Cesetti¹; E. von Molitor¹; R. Rudolf¹; M. Hafner¹; P. Scholz²; K. Riedel² ¹ Hochschule Mannheim, Mannheim/D; ² BRAIN AG, Zwingenberg/D
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Topic
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3.3 New devices for 3D cell culture
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P3.3.01
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Scaffold-Free Aggregate Cultivation of Mesenchymal Stem Cells in a Stirred Tank Bioreactor C. Kasper¹; D. Egger²; I. Schwedhelm³; J. Hansmann³; ¹ Boku, Vienna/A; ² DBT - University of Natural Resources and Life Sciences (BOKU), Vienna/A; ³ Translational Center, University Hospital Wuerzburg, Würzburg/D
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P3.3.02
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Guiding 3D cell migration in deformed synthetic hydrogel micro-structures M. Dietrich¹; H. Le Roy²; D. Brückner³; H. Engelke⁴; R. Zantl⁵; J. Rädler⁶; C. Broedersz³; ¹ Faculty of Physics and Center for NanoScience, Ludwig-Maximilians-University and ibidi GmbH, Munich/D; ² École Normale supérieure Paris-Saclay, Cachan/F; ³ Arnold-Sommerfeld Center for Theoretical Physics and Center for NanoScience, Ludwig-Maximilians-University, Munich/D; ⁴ Department of Chemistry and Center for NanoScience, Ludwig-Maximilians-University, Munich/D; ⁵ ibidi GmbH, Martinsried/D; ⁶ Faculty of Physics and Center for NanoScience, Ludwig-Maximilians-University, Munich/D
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P3.3.03
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Scaffold-Free Aggregate Cultivation of Mesenchymal Stem Cells in a Stirred Tank Bioreactor C. Kasper¹; ¹ University of Natural Resources and Life Sciences, Vienna, Vienna/A
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P3.3.04
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Development, Characterization and Application of a Parallelizable Perfusion Bioreactor for 3D Cell Culture D. Egger¹; M. Fischer¹; A. Clementi¹; J. Hansmann²; C. Kasper³; ¹ University of Natural Resources and Life Sciences, Vienna, Vienna/A; ² University Hospital Wuerzburg, Würzburg/D; ³ University of Natural Resources and Life Sciences, Vienna, Vienna/D
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P3.3.05
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A modular perfusion microbioreactor system for oxygen level control and optimization for bone tissue engineering J. Schmid¹; M. Schieker²; R. Huber¹; ¹ University of Applied Sciences Munich, Munich/D; ² Ludwig-Maximilians University Munich (LMU), Munich/D
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P3.3.06
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Gelatin-based hydrogels for 3D cell culture: stability at physiological temperatures by UV-crosslinking or nanoparticles K. Kruppa¹; A. Lavrentieva²; T. Scheper¹; I. Pepelanova³; ¹ Institute of Technical Chemistry, Leibniz University Hanover, Hannover/D; ² Institute of Technical Chemistry/Leibniz University Hanover, Hannover/D; ³ Institute of Technical Chemistry, Hannover/D
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P3.3.07
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A tubing-free, microfluidic tilting platform for the realization of in vivo-like drug exposure scenarios for three-dimensional microtissues C. Lohasz¹; O. Frey²; K. Renggli¹; A. Hierlemann¹; ¹ ETH Zürich, Basel/CH; ² Insphero AG, Schlieren/CH
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P3.3.08
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Organ-on-a-Disc – Enabling technology for the parallelization and automation of microphysiological systems S. Schneider¹; O. Schneider¹; F. Erdemann¹; C. Probst¹; P. Loskill¹; ¹ Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB, Stuttgart/D
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P3.3.09
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Porous, ultralight 3D tubular scaffolds from short electrospun nanofibers M. Merk¹; C. Adlhart¹; ¹ ZHAW Zürcher Hochschule für Angewandte Wissenschaften, Wädenswil/CH
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P3.3.10
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Enhanced cardiomyocyte maturation in a microfluidic system as a potential platform for pharmacological screening T. Kolanowski¹; M. Busek²; S. Grünzner³; F. Sonntag²; K. Guan¹; ¹ TU Dresden, Faculty of Medicine Carl Gustav Carus, Institute of Pharmacology and Toxicology, Dresden/D; ² Fraunhofer Institute of Material and Beam Technology IWS, Dresden/D; ³ Fraunhofer Institute of Material and Beam Technology IWS; TU Dresden, Faculty of Manufacturing Technology, Dresden/D
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P3.3.11
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Autonomous Plug&Play Multi-Organ-Chips with Integrated Pumping and Sensing F. Sonntag¹; C. Probst²; S. Grünzner³; M. Busek⁴; P. Loskill⁵; ¹ Fraunhofer-Institut für Werkstoff- und Strahltechnik IWS, Dresden/D; ² Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB, Stuttgart/D; ³ Fraunhofer Institute for Material and Beam Technology IWS / Dresden University of Technology, Dresden/D; ⁴ Fraunhofer Institute for Material and Beam Technology IWS, Dresden/D; ⁵ Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB / Eberhard Karls University Tübingen, Stuttgart/D
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P3.3.12
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vasQchip: A blood vessel scaffold for the reconstruction and 3D bioprinting of 3D-tissues in vitro U. Schepers¹; ¹ Karlsruhe Institute of Technology (KIT), Eggenstein-Leopoldshafen/D
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P3.3.13
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A non-invasive microscopy platform for the online monitoring of human induced pluripotent stem cell aggregation in suspension cultures in small-scale stirred tank bioreactors I. Schwedhelm¹; D. Egger²; P. Wiedemann³; T. Schwarz⁴; H. Walles¹; J. Hansmann⁴ ¹ University Hospital Würzburg, Würzburg/D; ² University of Natural Resources and Life Sciences, Vienna/A; ³ Mannheim University of Applied Sciences, Mannheim/D; ⁴ Fraunhofer Institute for Silicate Research ISC, Würzburg/D
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P3.3.14
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Comparison of 2D and 3D cultures of primary hepatocytes on hepatocellular functions and hepatotoxicity H. Dinter¹; A. Ullrich²; D. Runge² ¹ Hochschule Biberach, Biberach/D; ² Primacyt Cell Culture Technology GmbH, Schwerin/D
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P3.3.15 |
Funnel-Guided Positioning of Multi-cellular Microtissues to Build Macrotissues K. Manning¹; A. Thomson²; J. Morgan² ¹ Brown University, Providence, RI/USA; ² Brown University, Providence/USA |
P3.3.16 |
A novel 3D microwell array for analysis of adhesion independent micro-tumours A. Thomsen¹; C. Aldrian²; Y. Thomann³; A. Grosu²; P. Bronsert⁴; M. Leu⁵; P. Lund⁶ ¹ University Medical Center Freiburg, Freiburg/D; ² Medical Center – University of Freiburg, Freiburg/D; ³ Freiburg Material Research Center and Institute for Macromolecular Chemistry, Freiburg/D; ⁴ Institute for Surgical Pathology, Medical Center – University of Freiburg, Freiburg/D; ⁵ abc biopply ag, Solothurn/CH; ⁶ Department of Radiation Oncology, Ortenau-Klinikum, Offenburg/D |
P3.3.17 |
Integration of 3d printed hollow hydrogel fiber with microfluidic system to develop a perfusable nephron model. A. Akkineni¹; D. Förster²; J. Sardnick²; F. Schmieder³; F. Sonntag³; M. Gelinsky¹; A. Lode¹ ¹ Centre for Translational Bone, Joint and Soft Tissue Research, TU Dresden, Dresden/D; ² University Hospital Carl Gustav Carus, TU Dresden, Dresden/D; ³ Fraunhofer Institute for Material and Beam Technology IWS, Dresden/D |
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Topic
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3.5 High-throughput and automatisation
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P3.5.01
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Impedance analysis of viability of Schistosoma mansoni larvae for drug screening application M. Modena¹; K. Chawla¹; F. Lombardo²; S. Burgel¹; G. Panic²; J. Keiser²; A. Hierlemann¹; ¹ ETH Zürich; ² University of Basel
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P3.5.02
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Magnetic 3D Bioprinting for High-Throughput and Automated Hepatotoxicity Testing G. Souza¹; B. Larson²; ¹ The University of Texas Health Science Center, Houston/USA; ² Biotek Instruments, Inc., Winooski/USA
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P3.5.03
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Cytotoxicity Evaluation of Nanoparticles using Automatic 3D Cell Culture System M. Heo¹ ¹ Korea Research Institute of Standards and Science, Yuseong-gu, Daejeon/ROK
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P3.5.04
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Automated large-scale production and deposition of spheroids K. Tröndle¹; ¹ University of Freiburg, Technical Faculty, Freiburg/D
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Topic
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3.6 3D printing
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P3.6.01
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Characterization of GelMa and alginate hydrogels for bioprinting: printability, polymerization and biocompatibility L. Raddatz¹; C. Schmitz¹; P. Gellermann¹; M. Kirsch¹; D. Geier²; S. Beutel¹; T. Becker²; T. Scheper³; I. Pepelanova¹; A. Lavrentieva¹; ¹ Institute of Technical Chemistry, Leibniz University Hanover, Hannover/D; ² Institute of Brewing and Beverage Technology, Forschungszentrum Weihenstephan, Technical University Munich, Munich/D; ³ Institute of Technical Chemistry/Leibniz University Hanover, Hannover/D
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P3.6.03
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Engineering bio-mimetic vasculature with photolithographic fabrication techniques A. Thomas¹; K. Schimek¹; G. Giese²; A. Kreuder¹; T. Grix¹; L. Kloke³; ¹ Technische Universität Berlin, Berlin/D; ² Freie Universität Berlin, Berlin/D; ³ Cellbricks GmbH, Berlin/D
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P3.6.04
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Characterisation of bioprinted mandibular osteoblasts for engineering an in vitro jaw bone model A. Amler¹; A. Thomas¹; T. Grix¹; R. Lauster¹; L. Kloke² ¹ TU Berlin, Berlin/D; ² Cellbricks GmbH, Berlin/D
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P3.6.05
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3D Bioprinting of hydrogels for viral Infection and transduction with viral gene vectors T. Hiller¹; ¹ TU Berlin, Berlin/D
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P3.6.06
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3D-printed drug delivery systems for cell therapy: A new approach for the treatment of Diabetes Mellitus A. Pössl¹; P. Schlupp¹; T. Schmidts¹; F. Runkel¹ ¹ Technische Hochschule Mittelhessen, Gießen/D
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P3.6.07
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Imaging of O2 concentration and spatial distribution in 3D bioprinted hydrogel scaffolds using O2 sensing nanoparticles A. Akkineni¹; A. Lode¹; E. Trampe²; K. Koren²; F. Krujatz¹; M. Kühl²; M. Gelinsky¹ ¹ Technische Universität Dresden, Dresden/D; ² University of Copenhagen, Copenhagen/DK
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P3.6.08 |
Modelling of a microfluidic device to study tumor cell extravasation C. Kühlbach¹; R. Glunz¹; M. Mueller¹; F. Baganz²; V. Hass¹ ¹ HFU Hochschule Furtwangen University, Villingen-Schwenningen/D; ² UCL University College London, London/UK |